Search Results - "Kaku, Yoshiko"

Diarachidonoylphosphoethanolamine induces apoptosis of malignant pleural mesothelioma cells through a Trx/ASK1/p38 MAPK pathway by Tsuchiya, Ayako, Kaku, Yoshiko, Nakano, Takashi, Nishizaki, Tomoyuki

“…1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) induces both necrosis/necroptosis and apoptosis of NCI-H28 malignant pleural mesothelioma (MPM)…”
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HUHS1015 induces necroptosis and caspase-independent apoptosis of MKN28 human gastric cancer cells in association with AMID accumulation in the nucleus by Kaku, Yoshiko, Tsuchiya, Ayako, Kanno, Takeshi, Nishizaki, Tomoyuki

“…The newly synthesized naftopidil analogue HUHS1015 reduced viability of MKN28 and MKN45 human gastric cancer cells in a concentration (0.3-100 μM)-dependent…”
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Newly synthesized anticancer drug HUHS1015 is effective on malignant pleural mesothelioma by Kaku, Yoshiko, Nagaya, Hisao, Tsuchiya, Ayako, Kanno, Takeshi, Gotoh, Akinobu, Tanaka, Akito, Shimizu, Tadashi, Nakao, Syuhei, Tabata, Chiharu, Nakano, Takashi, Nishizaki, Tomoyuki

“…The newly synthesized naftopidil analogue HUHS1015 reduced cell viability in malignant pleural mesothelioma cell lines MSTO‐211H, NCI‐H28, NCI‐H2052, and…”
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1-[2-(2-Methoxyphenylamino)ethylamino]-3-(naphthalene-1- yloxy)propan-2-ol may be a promising anticancer drug by Nishizaki, Tomoyuki, Kanno, Takeshi, Tsuchiya, Ayako, Kaku, Yoshiko, Shimizu, Tadashi, Tanaka, Akito

“…We have originally synthesized the naftopidil analogue 1-[2-(2-methoxyphenylamino)ethylamino]-3-(naphthalene-1-yloxy)propan-2-ol (HUHS 1015) as a new…”
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HUHS1015 Suppresses Colonic Cancer Growth by Inducing Necrosis and Apoptosis in Association with Mitochondrial Damage by Kaku, Yoshiko, Tsuchiya, Ayako, Shimizu, Tadashi, Tanaka, Akito, Nishizaki, Tomoyuki

“…The newly-synthesized naftopidil analog HUHS1015 suppresses tumor growth and induces apoptosis of cells from a variety of cancer types. The present study was…”
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Dipalmitoleoyl-phosphatidylethanolamine induces apoptosis of NCI-H28 malignant mesothelioma cells by Kaku, Yoshiko, Tsuchiya, Ayako, Kanno, Takeshi, Nakano, Takashi, Nishizaki, Tomoyuki

“…The phospholipid phosphatidylethanolamine regulates a wide range of cellular processes. The present study investigated the antitumor effect of…”
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Irinotecan induces cell cycle arrest, but not apoptosis or necrosis, in Caco-2 and CW2 colorectal cancer cell lines by Kaku, Yoshiko, Tsuchiya, Ayako, Kanno, Takeshi, Nishizaki, Tomoyuki

“…Irinotecan, a topoisomerase I inhibitor, is clinically used as an anticancer drug. The present study investigated the anticancer effect of irinotecan on…”
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Phosphatidylinositol Derivatives Induce Gastric Cancer Cell Apoptosis by Accumulating AIF and AMID in the Nucleus by Ohyama, Masato, Tsuchiya, Ayako, Kaku, Yoshiko, Kanno, Takeshi, Shimizu, Tadashi, Tanaka, Akito, Nishizaki, Tomoyuki

“…The present study investigated the mechanism underlying the apoptosis of MKN28 human gastric cancer cells induced by the phosphatidylinositol (PI) derivative…”
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Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells by Kaku, Yoshiko, Tsuchiya, Ayako, Kanno, Takeshi, Nakano, Takashi, Nishizaki, Tomoyuki

“…The present study investigated 1,2-diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE)-induced cell death in malignant pleural mesothelioma (MPM) cells…”
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The newly synthesized anticancer drug HUHS1015 is useful for treatment of human gastric cancer by Kaku, Yoshiko, Tsuchiya, Ayako, Kanno, Takeshi, Nakao, Shuhei, Shimizu, Tadashi, Tanaka, Akito, Nishizaki, Tomoyuki

“…Naftopidil is clinically for treatment of benign prostate hyperplasia, and emerging evidence has pointed to its anticancer effect. To obtain the anticancer…”
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Characterization of atypical Aeromonas salmonicida isolated from an epizootic ulcerative disease in carp (Cyprinus carpio) by Kaku, Y. (Tokyo Univ. (Japan)), Yamada, Y, Wakabayashi, H

“…Since 1996, an epizootic ulcerative disease has affected both coloured-and common carp in Japan. We isolated atypical Aeromonas salmonicida from ulcerative…”
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Newly synthesized anticancer drug HUHS 1015 is effective on malignant pleural mesothelioma by Kaku, Yoshiko, Nagaya, Hisao, Tsuchiya, Ayako, Kanno, Takeshi, Gotoh, Akinobu, Tanaka, Akito, Shimizu, Tadashi, Nakao, Syuhei, Tabata, Chiharu, Nakano, Takashi, Nishizaki, Tomoyuki

“…The newly synthesized naftopidil analogue HUHS 1015 reduced cell viability in malignant pleural mesothelioma cell lines MSTO ‐211H, NCI ‐H28, NCI ‐H2052, and…”
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'FloraArray' for screening of specific DNA probes representing the characteristics of a certain microbial community by Yokoi, Takahide, Kaku, Yoshiko, Suzuki, Hiroyuki, Ohta, Masayuki, Ikuta, Hajime, Isaka, Kazuichi, Sumino, Tatsuo, Wagatsuma, Masako

“…To investigate uncharacterized microbial communities, a custom DNA microarray named 'FloraArray' was developed for screening specific probes that would…”
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‘FloraArray’ for screening of specific DNA probes representing the characteristics of a certain microbial community by Yokoi, Takahide, Kaku, Yoshiko, Suzuki, Hiroyuki, Ohta, Masayuki, Ikuta, Hajime, Isaka, Kazuichi, Sumino, Tatsuo, Wagatsuma, Masako

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国内で分離された非定型Aeromonas salmonicidaの16S rDNAによる系統解析 by 山田, 義行, 加来, 佳子, 若林, 久嗣

“…非定型Aeromonas salmonicidaの系統解析を16S rDNAの塩基配列の解析により行った結果,　国内で分離された菌株は,　キンギョ由来菌株,　ウナギおよび海産魚（ムシガレイ,　アイナメ,　ヒラメ,　クロソイ）由来菌株,　ニシキゴイ由来菌株,…”
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'FloraArray'for screening of specific DNA probes representing the characteristics of a certain microbial community by YOKOI, Takahide, KAKU, Yoshiko, SUZUKI, Hiroyuki, OHTA, Masayuki, IKUTA, Hajime, ISAKA, Kazuichi, SUMINO, Tatsuo, WAGATSUMA, Masako

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Phylogenetic intrarelationships of atypical Aeromonas salmonicida isolated in Japan as determined by 16S rDNA sequencing by Yamada, Y. (Tokyo Univ. (Japan)), Kaku, Y, Wakabayashi, H

“…Based on the nucleotide sequences of 16S rDNA, Japanese isolates of atypicalAeromonas salmonicidafrom different fish species can be divided into four groups;…”
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