Search Results - "Kakeno, Mai"

The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia by Kozawa, Kei, Sekai, Miho, Ohba, Kenji, Ito, Shoko, Sako, Hiroaki, Maruyama, Takeshi, Kakeno, Mai, Shirai, Takanobu, Kuromiya, Keisuke, Kamasaki, Tomoko, Kohashi, Koki, Tanaka, Shinya, Ishikawa, Susumu, Sato, Nanami, Asano, Shota, Suzuki, Hironori, Tanimura, Nobuyuki, Mukai, Yohei, Gotoh, Noriko, Tanino, Mishie, Tanaka, Shinya, Natsuga, Ken, Soga, Tomoyoshi, Nakamura, Tomonori, Yabuta, Yukihiro, Saitou, Mitinori, Ito, Takahiro, Matsuura, Kenkyo, Tsunoda, Makoto, Kikumori, Toyone, Iida, Tadashi, Mizutani, Yasuyuki, Miyai, Yuki, Kaibuchi, Kozo, Enomoto, Atsushi, Fujita, Yasuyuki

“…At the early stage of cancer development, oncogenic mutations often cause multilayered epithelial structures. However, the underlying molecular mechanism still…”
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PAR3-aPKC regulates Tiam1 by modulating suppressive internal interactions by Matsuzawa, Kenji, Akita, Hiroki, Watanabe, Takashi, Kakeno, Mai, Matsui, Toshinori, Wang, Shujie, Kaibuchi, Kozo

“…Tiam1 is one of the most extensively analyzed activators of the small GTPase Rac. However, fundamental aspects of its regulation are poorly understood. Here we…”
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EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells by Li, Wenjing, Miki, Tomohiro, Watanabe, Takashi, Kakeno, Mai, Sugiyama, Ikuko, Kaibuchi, Kozo, Goshima, Gohta

“…Highly conserved EB1 family proteins bind to the growing ends of microtubules, recruit multiple cargo proteins, and are critical for making dynamic…”
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PAR3 and aPKC regulate Golgi organization through CLASP2 phosphorylation to generate cell polarity by Matsui, Toshinori, Watanabe, Takashi, Matsuzawa, Kenji, Kakeno, Mai, Okumura, Nobumasa, Sugiyama, Ikuko, Itoh, Norimichi, Kaibuchi, Kozo

“…The organization of the Golgi apparatus is essential for cell polarization and its maintenance. The polarity regulator PAR complex (PAR3, PAR6, and aPKC) plays…”
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Plk1 Phosphorylates CLIP-170 and Regulates Its Binding to Microtubules for Chromosome Alignment by Kakeno, Mai, Matsuzawa, Kenji, Matsui, Toshinori, Akita, Hiroki, Sugiyama, Ikuko, Ishidate, Fumiyoshi, Nakano, Atsushi, Takashima, Seiji, Goto, Hidemasa, Inagaki, Masaki, Kaibuchi, Kozo, Watanabe, Takashi

“…The microtubule (MT) cytoskeleton is essential for cellular morphogenesis, cell migration, and cell division. MT organization is primarily mediated by a…”
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Ultrastructural Study of Rac1 and Its Effectors beneath the Substratum-Facing Membrane by Watanabe, Takashi, Wang, Shujie, Kakeno, Mai, Usukura, Jiro, Kaibuchi, Kozo

“…The cytoskeletal architecture and adhesion apparatus are tightly controlled during embryogenesis, tissue development, and carcinogenesis. The Rho family…”
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TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation by Watanabe, Takashi, Kakeno, Mai, Matsui, Toshinori, Sugiyama, Ikuko, Arimura, Nariko, Matsuzawa, Kenji, Shirahige, Aya, Ishidate, Fumiyoshi, Nishioka, Tomoki, Taya, Shinichiro, Hoshino, Mikio, Kaibuchi, Kozo

“…Microtubules (MTs) play critical roles in various cellular events, including cell migration. End-binding proteins (EBs) accumulate at the ends of growing MTs…”
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Numb controls E-cadherin endocytosis through p120 catenin with aPKC by Sato, Kazuhide, Watanabe, Takashi, Wang, Shujie, Kakeno, Mai, Matsuzawa, Kenji, Matsui, Toshinori, Yokoi, Keiko, Murase, Kiyoko, Sugiyama, Ikuko, Ozawa, Masayuki, Kaibuchi, Kozo

“…Cadherin trafficking controls tissue morphogenesis and cell polarity. The endocytic adaptor Numb participates in apicobasal polarity by acting on intercellular…”
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Phosphorylation of CLASP2 by GSK-3β regulates its interaction with IQGAP1, EB1 and microtubules by Watanabe, Takashi, Noritake, Jun, Kakeno, Mai, Matsui, Toshinori, Harada, Takumi, Wang, Shujie, Itoh, Norimichi, Sato, Kazuhide, Matsuzawa, Kenji, Iwamatsu, Akihiro, Galjart, Niels, Kaibuchi, Kozo

“…Polarised cell migration is required for various cell behaviours and functions. Actin and microtubules are coupled structurally and distributed asymmetrically…”
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Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration by Wang, Shujie, Watanabe, Takashi, Matsuzawa, Kenji, Katsumi, Akira, Kakeno, Mai, Matsui, Toshinori, Ye, Feng, Sato, Kazuhide, Murase, Kiyoko, Sugiyama, Ikuko, Kimura, Kazushi, Mizoguchi, Akira, Ginsberg, Mark H, Collard, John G, Kaibuchi, Kozo

“…Migrating cells acquire front-rear polarity with a leading edge and a trailing tail for directional movement. The Rac exchange factor Tiam1 participates in…”
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Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules by Watanabe, Takashi, Noritake, Jun, Kakeno, Mai, Matsui, Toshinori, Harada, Takumi, Wang, Shujie, Itoh, Norimichi, Sato, Kazuhide, Matsuzawa, Kenji, Iwamatsu, Akihiro, Galjart, Niels, Kaibuchi, Kozo

“…Polarised cell migration is required for various cell behaviours and functions. Actin and microtubules are coupled structurally and distributed asymmetrically…”
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