Search Results - "Kajiwara, Keiichi"

Aspirin-exacerbated respiratory disease (AERD): Current understanding of AERD by Taniguchi, Masami, Mitsui, Chihiro, Hayashi, Hiroaki, Ono, Emiko, Kajiwara, Keiichi, Mita, Haruhisa, Watai, Kentaro, Kamide, Yosuke, Fukutomi, Yuma, Sekiya, Kiyoshi, Higashi, Noritaka

“…The characteristics in AERD are severe adult-onset asthma, eosinophilic rhinosinusitis with nasal polyposis, and CysLT overproduction. The cause of AERD have…”
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Omalizumab reduces cysteinyl leukotriene and 9α,11β-prostaglandin F2 overproduction in aspirin-exacerbated respiratory disease by Hayashi, Hiroaki, MD, Mitsui, Chihiro, MD, Nakatani, Eiji, MS, Fukutomi, Yuma, MD, PhD, Kajiwara, Keiichi, BSc, Watai, Kentaro, MD, Sekiya, Kiyoshi, MD, Tsuburai, Takahiro, MD, PhD, Akiyama, Kazuo, MD, Hasegawa, Yoshinori, MD, PhD, Taniguchi, Masami, MD, PhD

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Platelet activation markers overexpressed specifically in patients with aspirin-exacerbated respiratory disease by Mitsui, Chihiro, MD, Kajiwara, Keiichi, BSc, Hayashi, Hiroaki, MD, Ito, Jun, MD, PhD, Mita, Haruhisa, PhD, Ono, Emiko, MD, PhD, Higashi, Noritaka, MD, PhD, Fukutomi, Yuma, MD, PhD, Sekiya, Kiyoshi, MD, Tsuburai, Takahiro, MD, PhD, Akiyama, Kazuo, MD, Yamamoto, Kazuhiko, MD, PhD, Taniguchi, Masami, MD, PhD

“…Background Aspirin-exacerbated respiratory disease (AERD) is characterized by respiratory reactions on ingestion of COX-1 inhibitors and cysteinyl leukotriene…”
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Low-dose mepolizumab is effective as an add-on therapy for treating long-lasting peripheral neuropathy in patients with eosinophilic granulomatosis with polyangiitis by Nakamura, Yuto, Fukutomi, Yuma, Sekiya, Kiyoshi, Kajiwara, Keiichi, Kawasaki, Yuichiro, Fujita, Norihiro, Nagayama, Kisako, Iwata, Maki, Iwamoto, Keisuke, Yano, Koichi, Hamada, Yuto, Watai, Kentaro, Ryu, Kai, Hayashi, Hiroaki, Kamide, Yosuke, Taniguchi, Masami

“…To assess the effectiveness of low-dose mepolizumab as an add-on therapy for treating peripheral neurological symptoms in eosinophilic granulomatosis with…”
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Profile of eicosanoid generation in aspirin-intolerant asthma and anaphylaxis assessed by new biomarkers by Higashi, Noritaka, MD, PhD, Mita, Haruhisa, PhD, Ono, Emiko, MD, PhD, Fukutomi, Yuma, MD, Yamaguchi, Hiromichi, MD, Kajiwara, Keiichi, BSc, Tanimoto, Hidenori, MD, Sekiya, Kiyoshi, MD, Akiyama, Kazuo, MD, Taniguchi, Masami, MD, PhD

“…Background It has recently demonstrated that a free radical–mediated pathway generates prostaglandins (PGs) and the corresponding prostaglandin enantiomers (…”
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Analysis of basophil activation in patients with aspirin-exacerbated respiratory disease by Mitsui, Chihiro, MD, Kajiwara, Keiichi, BSc, Ono, Emiko, MD, PhD, Watai, Kentaro, MD, Hayashi, Hiroaki, MD, Kamide, Yosuke, MD, PhD, Fukutomi, Yuma, MD, PhD, Sekiya, Kiyoshi, MD, Tsuburai, Takahiro, MD, PhD, Yamamoto, Kazuhiko, MD, PhD, Taniguchi, Masami, MD, PhD

“…Basophils are a major source of cysteinyl leukotrienes, but little is known about their association with the pathogenesis of aspirin-exacerbated respiratory…”
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A Survey of Actual Clinical Practice Concerning Blood Pressure Control among Patients with Hypertension in Kanagawa 2014 by Hatori, Nobuo, Sakai, Hiroyuki, Sato, Kazuyoshi, Miyajima, Masayuki, Yuasa, Shouhei, Kuboshima, Shingo, Kajiwara, Keiichi, Hara, Yoshikuni, Minamizawa, Kousuke, Miyakawa, Masaaki

“…We performed a cross-sectional survey to investigate actual clinical practice concerning blood-pressure control among patients with hypertension in Kanagawa…”
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Suppression of Lipid Mediators By the Humanized Anti-IgE Antibody Omalizumab in Aspirin-Exacerbated Respiratory Disease by Hayashi, Hiroaki, MD, Mitsui, Chihiro, MD, Fukutomi, Yuma, MD, PhD, Kajiwara, Keiichi, BSc, Watai, Kentaro, MD, Kinoshita, Arisa, MD, Kamide, Yosuke, MD, PhD, Sekiya, Kiyoshi, MD, Tsuburai, Takahiro, MD, PhD, Mori, Akio, MD, PhD, Akiyama, Kazuo, MD, Hasegawa, Yoshinori, MD, PhD, Taniguchi, Masami, MD, PhD

“…Conclusions Omalizumab was an effective treatment in AERD patients with severe asthmatic and nasal symptoms, and reduced mast cell activation and leukotriene…”
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Is There Any Basophil Activation in Peripheral Blood in AERD Patients? by Mitsui, Chihiro, MD, Ono, Emiko, MD, Kajiwara, Keiichi, BSc, Hayashi, Hiroaki, MD, Kamide, Yosuke, MD, PhD, Watai, Kentaro, MD, Kinoshita, Arisa, MD, Fukutomi, Yuma, MD, PhD, Sekiya, Kiyoshi, MD, Tsuburai, Takahiro, MD, PhD, Mori, Akio, MD, PhD, Taniguchi, Masami, MD, PhD

“…Longitudinal changes in these expression levels were measured after basophil stimulation by IgE-dependent or IgE-independent (IL3 stimulated) mechanisms and…”
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Omalizumab for Aspirin Hypersensitivity and Leukotriene Overproduction in Aspirin-exacerbated Respiratory Disease. A Randomized Controlled Trial by Hayashi, Hiroaki, Fukutomi, Yuma, Mitsui, Chihiro, Kajiwara, Keiichi, Watai, Kentaro, Kamide, Yosuke, Nakamura, Yuto, Hamada, Yuto, Tomita, Yasuhiro, Sekiya, Kiyoshi, Tsuburai, Takahiro, Izuhara, Kenji, Wakahara, Keiko, Hashimoto, Naozumi, Hasegawa, Yoshinori, Taniguchi, Masami

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Expression and Function of the Inducible Costimulator Ligand B7-H2 in Human Airway Smooth Muscle Cells by Kajiwara, Keiichi, Morishima, Hirotaka, Akiyama, Kazuo, Yanagihara, Yukiyoshi

“…Background: B7-H2 is a ligand for the inducible costimulator (ICOS). The aim of this study was to examine the expression and function of B7-H2 in human airway…”
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Changes in blood-pressure control among patients with hypertension from 2008 through 2011: surveys of actual clinical practice by Hatori, Nobuo, Sakai, Hiroyuki, Sato, Kazuyoshi, Mitani, Kazuhiko, Miyajima, Masayuki, Yuasa, Shouhei, Kuboshima, Shingo, Kajiwara, Keiichi, Miyakawa, Masaaki

“…We performed cross-sectional surveys to investigate changes in clinical practices regarding blood-pressure control in patients with hypertension from 2008…”
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Ligation of Toll-like receptor 3 differentially regulates M2 and M3 muscarinic receptor expression and function in human airway smooth muscle cells by Morishima, Hirotaka, Kajiwara, Keiichi, Akiyama, Kazuo, Yanagihara, Yukiyoshi

“…Viral infection causes asthma exacerbations and airway hyperreactivity. Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) of viral or…”
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Changes in Blood-pressure Control among Patients with Hypertension from 2008 through 2011: Surveys of Actual Clinical Practice by Hatori, Nobuo, Sakai, Hiroyuki, Sato, Kazuyoshi, Mitani, Kazuhiko, Miyajima, Masayuki, Yuasa, Shouhei, Kuboshima, Shingo, Kajiwara, Keiichi, Miyakawa, Masaaki

“…We performed cross-sectional surveys to investigate changes in clinical practices regarding blood-pressure control in patients with hypertension from 2008…”
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A Survey of Actual Clinical Practice Concerning Blood Pressure Control among Patients with Hypertension in Kanagawa 2014 by Nobuo Hatori, Hiroyuki Sakai, Kazuyoshi Sato, Masayuki Miyajima, Shouhei Yuasa, Shingo Kuboshima, Keiichi Kajiwara, Yoshikuni Hara, Kousuke Minamizawa, Masaaki Miyakawa

“…We performed a cross-sectional survey to investigate actual clinical practice concerning blood-pressure control among patients with hypertension in Kanagawa…”
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Omalizumab for Aspirin Hypersensitivity and Leukotriene Overproduction in Aspirin-exacerbated Respiratory Disease. A Randomized Controlled Trial by Hayashi, Hiroaki, Fukutomi, Yuma, Mitsui, Chihiro, Kajiwara, Keiichi, Watai, Kentaro, Kamide, Yosuke, Nakamura, Yuto, Hamada, Yuto, Tomita, Yasuhiro, Sekiya, Kiyoshi, Tsuburai, Takahiro, Izuhara, Kenji, Wakahara, Keiko, Hashimoto, Naozumi, Hasegawa, Yoshinori, Taniguchi, Masami

“…A study that evaluates the efficacy of omalizumab against aspirin hypersensitivity, leukotriene E4 overproduction and symptoms during an oral aspirin challenge…”
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Differential effect of IL-4 and IL-13 on the expression of recombination-activating genes in mature B cells from human peripheral blood by Kajiwara, Keiichi, Shinazawa, Miki, Morishima, Hirotaka, Yanagihara, Yukiyoshi

“…We examined the expression of recombination-activating genes (RAG-1 and RAG-2) and activation-induced cytidine deaminase (AID) by mature human blood B cells…”
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Omalizumab ameliorates extrarespiratory symptoms in patients with aspirin-exacerbated respiratory disease by Hayashi, Hiroaki, Fukutomi, Yuma, Mitsui, Chihiro, Kajiwara, Keiichi, Watai, Kentaro, Tomita, Yasuhiro, Kamide, Yosuke, Tsuburai, Takahiro, Sekiya, Kiyoshi, Ishii, Makoto, Hasegawa, Yoshinori, Taniguchi, Masami

“…Omalizumab, an anti-IgE antibody, has clinical efficacy against respiratory symptoms of aspirin-exacerbated respiratory disease (AERD). However, some patients…”
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Recombinant soluble form of the high-affinity IgE receptor α subunit and anti-IgE antibody inhibit IgE synthesis by IgE-expressing B cells through distinct pathways by Kajiwara, Keiichi, Ra, Chisei, Yanagihara, Yukiyoshi

“…Both a recombinant soluble form of the high-affinity IgE receptor α subunit (rsFcεRIα) and anti-IgE antibody have been shown to be involved in the regulation…”
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Efficacy of Omalizumab against Aspirin-hypersensitivity and Overproduction of Cysteinyl Leukotrienes in Aspirin-exacerbated Respiratory Disease: A Randomized Trial by Hayashi, Hiroaki, Fukutomi, Yuma, Mitsui, Chihiro, Kajiwara, Keiichi, Watai, Kentaro, Kamide, Yosuke, Iwata, Maki, Nagayama, Kisako, Nakamura, Yuto, Hamada, Yuto, Tomita, Yasuhiro, Sekiya, Kiyoshi, Tsuburai, Takahiro, Mori, Akio, Izuhara, Kenji, Wakahara, Keiko, Hashimoto, Naozumi, Hasegawa, Yoshinori, Taniguchi, Masami

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