Search Results - "Kaji, Takayuki"
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Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle
Published in eLife (23-09-2019)“…In overloaded and regenerating muscle, the generation of new myonuclei depends on muscle satellite cells (MuSCs). Because MuSC behaviors in these two…”
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The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells
Published in Cell reports (Cambridge) (19-11-2019)“…Quiescence is a fundamental property of adult stem cells. Recent evidence indicates that quiescence is not a default state but requires active signaling that…”
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Regulation of muscle hypertrophy through granulin: Relayed communication among mesenchymal progenitors, macrophages, and satellite cells
Published in Cell reports (Cambridge) (23-04-2024)“…Skeletal muscles exert remarkable regenerative or adaptive capacities in response to injuries or mechanical loads. However, the cellular networks underlying…”
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Journal Article -
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Dlk1 regulates quiescence in calcitonin receptor‐mutant muscle stem cells
Published in Stem cells (Dayton, Ohio) (01-03-2021)“…Muscle stem cells, also called muscle satellite cells (MuSCs), are responsible for skeletal muscle regeneration and are sustained in an undifferentiated and…”
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Expression and Functional Analyses of Dlk1 in Muscle Stem Cells and Mesenchymal Progenitors during Muscle Regeneration
Published in International journal of molecular sciences (03-07-2019)“…Delta like non-canonical Notch ligand 1 ( ) is a paternally expressed gene which is also known as preadipocyte factor 1 ( ). The accumulation of adipocytes and…”
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Detection of muscle stem cell-derived myonuclei in murine overloaded muscles
Published in STAR protocols (17-06-2022)“…Muscle satellite cells (MuSCs) supply nuclei to existing myofibers in response to mechanical loading. This myonuclear accretion is critical for efficient…”
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Journal Article -
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Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load
Published in Cell stem cell (03-02-2022)“…Adaptation to mechanical load, leading to enhanced force and power output, is a characteristic feature of skeletal muscle. Formation of new myonuclei required…”
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Robust molten steel level control for continuous casting
Published in Proceedings of 35th IEEE Conference on Decision and Control (1996)“…This paper presents a new control method for stabilizing the molten steel level in the molding process of a continuous casting mill. A disturbance observer is…”
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