Search Results - "Kajdácsi, Erika"

Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history by Kiszel, Petra, Sík, Pál, Miklós, János, Kajdácsi, Erika, Sinkovits, György, Cervenak, László, Prohászka, Zoltán

“…Vaccinations against SARS-CoV-2 reduce the risk of developing serious COVID-19 disease. Monitoring spike-specific IgG subclass levels after vaccinations may…”
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Decreased adhesion to endothelium leads to elevated neutrophil granulocyte count in hereditary angioedema patients by Kajdácsi, Erika, Balla, Zsuzsanna, Pólai, Zsófia, Cervenak, László, Farkas, Henriette

“…As many aspects of hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency (C1-INH-HAE) cannot be explained with elevated bradykinin level alone,…”
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Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection by Sinkovits, György, Mező, Blanka, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Csuka, Dorottya, Hurler, Lisa, Kajdácsi, Erika, Cervenak, László, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán

“…Uncontrolled thromboinflammation plays an important role in the pathogenesis of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus. Complement was…”
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Detrimental interactions of hypoxia and complement MASP-1 in endothelial cells as a model for atherosclerosis-related diseases by Demeter, Flóra, Németh, Zsuzsanna, Kajdácsi, Erika, Bihari, György, Dobó, József, Gál, Péter, Cervenak, László

“…Both hypoxia and the complement lectin pathway (CLP) are involved in atherosclerosis and atherosclerosis-related stroke and acute myocardial infarction (AMI)…”
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“Nuts and Bolts” of Laboratory Evaluation of Angioedema by Farkas, Henriette, Veszeli, Nóra, Kajdácsi, Erika, Cervenak, László, Varga, Lilian

“…Angioedema, as a distinct disease entity, often becomes a clinical challenge for physicians, because it may cause a life-threatening condition, whereas prompt…”
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Molecular Dambusters: What Is Behind Hyperpermeability in Bradykinin-Mediated Angioedema? by Debreczeni, Márta L., Németh, Zsuzsanna, Kajdácsi, Erika, Farkas, Henriette, Cervenak, László

“…In the last few decades, a substantial body of evidence underlined the pivotal role of bradykinin in certain types of angioedema. The formation and breakdown…”
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Neutrophils produce proinflammatory or anti‐inflammatory extracellular vesicles depending on the environmental conditions by Kolonics, Ferenc, Kajdácsi, Erika, Farkas, Veronika J., Veres, Dániel S., Khamari, Delaram, Kittel, Ágnes, Merchant, Michael L., McLeish, Kenneth R., Lőrincz, Ákos M., Ligeti, Erzsébet

“…Extracellular vesicles (EVs) are important elements of intercellular communication. A plethora of different, occasionally even opposite, physiologic and…”
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Cooperation of Complement MASP-1 with Other Proinflammatory Factors to Enhance the Activation of Endothelial Cells by Németh, Zsuzsanna, Debreczeni, Márta L, Kajdácsi, Erika, Dobó, József, Gál, Péter, Cervenak, László

“…Endothelial cells play an important role in sensing danger signals and regulating inflammation. Several factors are capable of inducing a proinflammatory…”
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Evidence, detailed characterization and clinical context of complement activation in acute multisystem inflammatory syndrome in children by Sinkovits, György, Schnur, János, Hurler, Lisa, Kiszel, Petra, Prohászka, Zita Z., Sík, Pál, Kajdácsi, Erika, Cervenak, László, Maráczi, Veronika, Dávid, Máté, Zsigmond, Borbála, Rimanóczy, Éva, Bereczki, Csaba, Willems, Loek, Toonen, Erik J. M., Prohászka, Zoltán

“…Multisystem inflammatory syndrome in children (MIS-C) is a rare, life-threatening complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Associations between the von Willebrand Factor-ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality by Sinkovits, György, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Mező, Blanka, Csuka, Dorottya, Hurler, Lisa, Kajdácsi, Erika, Cervenak, László, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán

“…Endothelial and complement activation were both associated with immunothrombosis, a key determinant of COVID-19 severity, but their interrelation has not yet…”
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Patterns of C1-Inhibitor/Plasma Serine Protease Complexes in Healthy Humans and in Hereditary Angioedema Patients by Kajdácsi, Erika, Jandrasics, Zsófia, Veszeli, Nóra, Makó, Veronika, Koncz, Anna, Gulyás, Dominik, Köhalmi, Kinga Viktória, Temesszentandrási, György, Cervenak, László, Gál, Péter, Dobó, József, de Maat, Steven, Maas, Coen, Farkas, Henriette, Varga, Lilian

“…C1-inhibitor (C1-INH) is an important regulator of the complement, coagulation, fibrinolytic and contact systems. The quantity of protease/C1-INH complexes in…”
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Anti-Inflammatory Cytokine Profiles in Thrombotic Thrombocytopenic Purpura-Differences Compared to COVID-19 by Demeter, Flóra, Bihari, György, Vadicsku, Dorina, Sinkovits, György, Kajdácsi, Erika, Horváth, Laura, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán, Cervenak, László

“…Thromboinflammation/immunothrombosis plays a role in several diseases including thrombotic thrombocytopenic purpura (TTP) and COVID-19. Unlike the extensive…”
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Storage of Transfusion Platelet Concentrates Is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor by Andersson, Linnea I, Sjöström, Dick J, Quach, Huy Quang, Hägerström, Kim, Hurler, Lisa, Kajdácsi, Erika, Cervenak, László, Prohászka, Zoltán, Toonen, Erik J M, Mohlin, Camilla, Mollnes, Tom Eirik, Sandgren, Per, Tjernberg, Ivar, Nilsson, Per H

“…Platelet activation and the complement system are mutually dependent. Here, we investigated the effects of storage time on complement activation and platelet…”
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MASP-1 Increases Endothelial Permeability by Debreczeni, Márta L, Németh, Zsuzsanna, Kajdácsi, Erika, Schwaner, Endre, Makó, Veronika, Masszi, András, Doleschall, Zoltán, Rigó, János, Walter, Fruzsina R, Deli, Mária A, Pál, Gábor, Dobó, József, Gál, Péter, Cervenak, László

“…Pathologically increased vascular permeability is an important dysfunction in the pathomechanism of life-threatening conditions, such as sepsis,…”
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Pathways of Neutrophil Granulocyte Activation in Hereditary Angioedema with C1 Inhibitor Deficiency by Kajdácsi, Erika, Veszeli, Nóra, Mező, Blanka, Jandrasics, Zsófia, Kőhalmi, Kinga Viktória, Ferrara, Anne Lise, Cervenak, László, Varga, Lilian, Farkas, Henriette

“…Hereditary angioedema (HAE) with C1-inhibitor deficiency belongs to bradykinin-mediated angioedemas. It is characterized by recurrent subcutaneous and/or…”
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Endothelial cell activation during edematous attacks of hereditary angioedema types I and II by Kajdácsi, Erika, MSc, Jani, Péter K., MSc, Csuka, Dorottya, PhD, Varga, Lilian Ágnes, PhD, Prohászka, Zoltán, MD, DSc, Farkas, Henriette, MD, DSc, Cervenak, László, PhD

“…Background Hereditary angioedema (HAE) caused by C1-inhibitor (C1-INH) deficiency (HAE–C1-INH) is a potentially life-threatening rare disease caused by the…”
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MASP-1 induces a unique cytokine pattern in endothelial cells: a novel link between complement system and neutrophil granulocytes by Jani, Péter K, Kajdácsi, Erika, Megyeri, Márton, Dobó, József, Doleschall, Zoltán, Futosi, Krisztina, Tímár, Csaba I, Mócsai, Attila, Makó, Veronika, Gál, Péter, Cervenak, László

“…Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this…”
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sMR and PTX3 levels associate with COVID-19 outcome and survival but not with Long COVID by Hurler, Lisa, Mescia, Federica, Bergamaschi, Laura, Kajdácsi, Erika, Sinkovits, György, Cervenak, László, Prohászka, Zoltán, Lyons, Paul A., Toonen, Erik J.M.

“…Biomarkers for monitoring COVID-19 disease course are lacking. Study aim was to identify biomarkers associated with disease severity, survival, long-term…”
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Atrial natriuretic peptide as a novel biomarker of hereditary angioedema by Kajdácsi, Erika, Varga, Lilian, Prohászka, Zoltán, Farkas, Henriette, Cervenak, László

“…Highlights • ANP level is lower in C1-INH HAE patients than in control subjects, and it remains unchanged during edematous attacks. • Neither cardiac risk, nor…”
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Flow-mediated vasodilation assay indicates no endothelial dysfunction in hereditary angioedema patients with C1-inhibitor deficiency by Nebenführer, Zsuzsa, Szabó, Erika, Kajdácsi, Erika, Kőhalmi, Kinga Viktória, Karádi, István, Zsáry, András, Farkas, Henriette, Cervenak, László

“…Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is a rare, potentially life-threatening disorder characterized by recurrent edematous attacks…”
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