Search Results - "Kaita, Kelly D."

A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients by Bain, Vincent G., Kaita, Kelly D., Yoshida, Eric M., Swain, Mark G., Heathcote, E. Jenny, Neumann, Avidan U., Fiscella, Michele, Yu, Ren, Osborn, Blaire L., Cronin, Patrick W., Freimuth, William W., McHutchison, John G., Subramanian, G. Mani

“…Background/Aims : Recombinant human albumin-interferon alfa (alb-IFN) is a novel 85.7-kD recombinant protein consisting of interferon alfa-2b genetically fused…”
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Concomitant nonalcoholic fatty liver disease does not alter the activity, severity or course of primary biliary cholangitis by Minuk, Gerald Y., Iliant, Venera, Zhou, Nancy, Kaita, Kelly D., Wong, Stephen G., Peretz, David, Uhanova, Julia

“…Background & Aims The impact of nonalcoholic fatty liver disease (NAFLD) on the natural history of primary biliary cholangitis (PBC) has yet to be described…”
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Safety and Antiviral Activity of Albinterferon Alfa-2b Dosed Every Four Weeks in Genotype 2/3 Chronic Hepatitis C Patients by Bain, Vincent G, Kaita, Kelly D, Marotta, Paul, Yoshida, Eric M, Swain, Mark G, Bailey, Robert J, Patel, Keyur, Cronin, Patrick W, Pulkstenis, Erik, McHutchison, John G, Subramanian, G. Mani

“…Background & Aims: A phase 2, randomized, multicenter, open-label study evaluated the safety and efficacy of albinterferon alfa-2b in interferon-α…”
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Genomic analysis of a recently identified virus (SEN virus) and genotypes D and H by polymerase chain reaction by Kojima, Hiroshige, Kaita, Kelly D.E., Zhang, Manna, Giulivi, Antonio, Minuk, Gerald Y.

“…Background/Aims: SEN virus (SENV) was discovered in 1999 as a DNA virus with hepatotropic properties. Nine genotypes (A–I) have been identified with genotypes…”
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The absence of up-regulation of telomerase activity during regeneration after partial hepatectomy in hepatitis B virus X gene transgenic mice by Kojima, Hiroshige, Kaita, Kelly D.E, Xu, Zhenming, Ou, James H, Gong, Yuewen, Zhang, Manna, Minuk, Gerald Y

“…Background/Aims: Transgenic mice that express HBV X protein (HBx) have increased sensitivity to hepatocarcinogens. In the present study, we hypothesized that…”
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Serum cholesterol and low-density lipoprotein cholesterol levels as predictors of response to interferon therapy for chronic hepatitis C by Minuk, G Y, Weinstein, S, Kaita, K D

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The beneficial effects of ciprofloxacin on survival and hepatic regenerative activity in a rat model of fulminant hepatic failure by Kaita, Kelly D., Assy, Nimar, Gauthier, Tony, Zhang, Manna, Meyers, Adrienne F., Minuk, Gerald Y.

“…Recently, we reported that ciprofloxacin, an antimicrobial agent with γ‐aminobutyric acid (GABAA ) receptor antagonist properties, significantly increases…”
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The differential effects of three forms of interferon alfa on hepatic regeneration after partial hepatectomy in the rat by Wong, S, Gauthier, T, Kaita, K D, Minuk, G Y

“…The purpose of this study was to determine whether all commercially available forms of interferon alfa (INF alpha) have the same inhibitory effect on hepatic…”
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Treatment outcomes in a centralized specialty clinic for hepatitis C virus are comparable with those from clinical trials by De Kaita, Kelly, Wong, Stephen, Renner, Eberhard, Minuk, Gerald Y

“…Outcomes from industry-sponsored registration trials are often considered to be more favourable than those achieved in clinical practice because patients…”
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