Search Results - "Kaiser, Steffen"
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Basic Conditions for Support of Young Carers in School: A Secondary Analysis of the Perspectives of Young Carers, Parents, Teachers, and Counselors
Published in Healthcare (Basel) (01-06-2024)“…Young carers face a variety of challenges at school. While schools can be vital places of support, the assistance they receive at school often seems selective…”
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2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells
Published in Journal of innate immunity (01-01-2015)“…Microbial RNA is an important stimulator of innate immune responses. Differences in posttranscriptional RNA modification profiles enable the immune system to…”
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Who are „Young Carers”? Analysis of the Use of the Term in German Speaking Countries and Development of a Definition / Wer sind Young Carers? Analyse der Begriffsverwendung im deutschsprachigen Raum und Entwicklung einer Definition
Published in International Journal of Health Professions (Warsaw, Poland) (12-03-2019)“…Children and adolescents with caring responsibility who are looking after a family member or a person close are often hiding from the view of the public. They…”
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Influence of aging, morphology and particle size on the behavior of microplastics during magnetic seeded filtration
Published in The Science of the total environment (20-12-2024)“…Magnetic seeded filtration (MSF) is a solid-liquid separation process based on the formation of hetero-agglomerates between target (non-magnetic) particles and…”
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5
Opportunities and Challenges to Profile mRNA Modifications in Escherichia coli
Published in Chembiochem : a European journal of chemical biology (16-09-2022)“…mRNA methylation is an important regulator of many physiological processes in eukaryotes but has not been studied in depth in prokaryotes. Working with…”
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Agglomerate processing and recycling options in magnetic seeded filtration
Published in Chemical engineering science (20-07-2021)“…[Display omitted] •Magnetic seeded filtration is a new and versatile solid–liquid separation process.•Three recycling approaches of magnetic seed particles are…”
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Person–Environment Analysis: A Framework for Participatory Holistic Research
Published in Gestalt Theory (01-04-2018)“…This article presents the person–environment analysis as a framework for participatory and holistic research. By using common methods of qualitative research…”
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Surpassing limits of static RNA modification analysis with dynamic NAIL-MS
Published in Methods (San Diego, Calif.) (01-03-2019)“…[Display omitted] •NAIL-MS is the first tool which allows the observation of RNA modification dynamics in vivo.•Types of NAIL-MS experiments.•Nucleic acid…”
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The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA
Published in RNA biology (02-09-2017)“…The amino acid sequence of Dnmt2 is very similar to the catalytic domains of bacterial and eukaryotic DNA-(cytosine 5)-methyltransferases, but it efficiently…”
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Production and purification of endogenously modified tRNA-derived small RNAs
Published in RNA biology (02-08-2020)“…During particular stress conditions, transfer RNAs (tRNAs) become substrates of stress-induced endonucleases, resulting in the production of distinct…”
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Strategies to Avoid Artifacts in Mass Spectrometry‐Based Epitranscriptome Analyses
Published in Angewandte Chemie International Edition (25-10-2021)“…In this report, we perform structure validation of recently reported RNA phosphorothioate (PT) modifications, a new set of epitranscriptome marks found in…”
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A modified dinucleotide motif specifies tRNA recognition by TLR7
Published in RNA (Cambridge) (01-09-2014)“…RNA can function as a pathogen-associated molecular pattern (PAMP) whose recognition by the innate immune system alerts the body to an impending microbial…”
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Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences
Published in Cell discovery (09-06-2015)“…The Dnmt2 RNA methyltransferase catalyses the methylation of C38 in the anticodon loop of tRNA-Asp, but the molecular role of this methylation is unknown…”
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14
Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity
Published in The Journal of experimental medicine (13-02-2012)“…Naturally occurring nucleotide modifications within RNA have been proposed to be structural determinants for innate immune recognition. We tested this…”
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Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs
Published in Nucleic acids research (20-02-2020)“…Abstract tRNAs from all domains of life contain modified nucleotides. However, even for the experimentally most thoroughly characterized model organism…”
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Recognition of Specified RNA Modifications by the Innate Immune System
Published in Methods in enzymology (01-01-2015)“…Microbial nucleic acids have been described as important activators of human innate immune responses by triggering so-called pattern recognition receptors…”
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The rRNA m 6 A methyltransferase METTL5 is involved in pluripotency and developmental programs
Published in Genes & development (01-05-2020)“…Covalent chemical modifications of cellular RNAs directly impact all biological processes. However, our mechanistic understanding of the enzymes catalyzing…”
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The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs
Published in Genes & development (01-05-2020)“…In this study, Ignatova et al. performed a systematic screen to uncover new RNA methyltransferases, and demonstrate that the methyltransferase-like 5 (METTL5)…”
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Between Inclusion and Participation: Young Carers Who Are Absent From School
Published in Journal of cognitive education and psychology (01-01-2015)“…In discussions of inclusion and exclusion, one often-neglected group at high risk of exclusion is that of school absentees. Researchers and the public normally…”
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Strategien zur Vermeidung von Artefakten in der massenspektrometrischen Epitranskriptomanalytik
Published in Angewandte Chemie (25-10-2021)“…In diesem Artikel führen wir eine Strukturvalidierung von RNA‐Phosphorothioat (PT)‐Modifikationen durch, von welchen vor Kurzem im Epitranskriptom von…”
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