Search Results - "Kaiser, Nathan K."
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21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis
Published in Journal of the American Society for Mass Spectrometry (01-09-2015)“…We describe the design and initial performance of the first 21 tesla Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. The 21 tesla magnet…”
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Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry
Published in Journal of proteome research (03-02-2017)“…Successful high-throughput characterization of intact proteins from complex biological samples by mass spectrometry requires instrumentation capable of high…”
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3
Metallofullerene and fullerene formation from condensing carbon gas under conditions of stellar outflows and implication to stardust
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2013)“…Carbonaceous presolar grains of supernovae origin have long been isolated and are determined to be the carrier of anomalous ²²Ne in ancient meteorites. That…”
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Bottom-up formation of endohedral mono-metallofullerenes is directed by charge transfer
Published in Nature communications (19-12-2014)“…An understanding of chemical formation mechanisms is essential to achieve effective yields and targeted products. One of the most challenging endeavors is…”
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Controlled Ion Ejection from an External Trap for Extended m/z Range in FT-ICR Mass Spectrometry
Published in Journal of the American Society for Mass Spectrometry (01-06-2014)“…An auxiliary rf waveform of the same amplitude and phase applied to all the rods of an ion accumulation multipole creates an m/z -dependent axial pseudo…”
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Unprecedented Ultrahigh Resolution FT-ICR Mass Spectrometry and Parts-Per-Billion Mass Accuracy Enable Direct Characterization of Nickel and Vanadyl Porphyrins in Petroleum from Natural Seeps
Published in Energy & fuels (17-04-2014)“…The most abundant and problematic metal compounds in crude oil exist as organic complexes of vanadium and nickel in porphyrin structures derived from…”
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Front-End Electron Transfer Dissociation Coupled to a 21 Tesla FT-ICR Mass Spectrometer for Intact Protein Sequence Analysis
Published in Journal of the American Society for Mass Spectrometry (01-09-2017)“…High resolution mass spectrometry is a key technology for in-depth protein characterization. High-field Fourier transform ion cyclotron resonance mass…”
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Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Published in Analytical chemistry (Washington) (15-11-2011)“…Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) provides the highest mass resolving power and mass measurement accuracy for unambiguous…”
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Use of a Novel Whole Blood Separation and Transport Device for Targeted and Untargeted Proteomics
Published in Biomedicines (11-10-2024)“…There is significant interest in developing alternatives to traditional blood transportation and separation methods, which often require centrifugation and…”
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Formation of Heterofullerenes by Direct Exposure of C60 to Boron Vapor
Published in Angewandte Chemie International Edition (02-01-2013)“…Introducing boron: Heterofullerenes that incorporate boron have been scarcely studied because a formation route from C60 is not known. It is now reported that…”
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Design and Characterization of a Novel Blood Collection and Transportation Device for Proteomic Applications
Published in Diagnostics (Basel) (02-12-2020)“…A major hurdle for blood-based proteomic diagnostics is efficient transport of specimens from the collection site to the testing laboratory. Dried blood spots…”
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Chemical cross-linking and mass spectrometry enabled systems-level structural biology
Published in Current opinion in structural biology (01-08-2024)“…Structural information on protein–protein interactions (PPIs) is essential for improved understanding of regulatory interactome networks that confer various…”
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A Novel 9.4 Tesla FTICR Mass Spectrometer with Improved Sensitivity, Mass Resolution, and Mass Range
Published in Journal of the American Society for Mass Spectrometry (01-08-2011)“…Fourier transform ion cyclotron resonance (FTICR) mass spectrometry provides unparalleled mass measurement accuracy and resolving power. However, propagation…”
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A bifunctional monolithic column for combined protein preconcentration and digestion for high throughput proteomics research
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-04-2007)“…Enzymatic digestion of proteins is a key step in protein identification by mass spectrometry (MS). Traditional solution-based protein digestion methods require…”
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Expansion of the Analytical Window for Oil Spill Characterization by Ultrahigh Resolution Mass Spectrometry: Beyond Gas Chromatography
Published in Environmental science & technology (02-07-2013)“…Traditional tools for routine environmental analysis and forensic chemistry of petroleum have relied almost exclusively on gas chromatography–mass spectrometry…”
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The Smallest Stable Fullerene, M@C28 (M = Ti, Zr, U): Stabilization and Growth from Carbon Vapor
Published in Journal of the American Chemical Society (06-06-2012)“…The smallest fullerene to form in condensing carbon vapor has received considerable interest since the discovery of Buckminsterfullerene, C60. Smaller…”
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Parts-Per-Billion Fourier Transform Ion Cyclotron Resonance Mass Measurement Accuracy with a “Walking” Calibration Equation
Published in Analytical chemistry (Washington) (01-03-2011)“…Ion cyclotron resonance frequency, f, is conventionally converted to ion mass-to-charge ratio, m/z (mass “calibration”) by fitting experimental data spanning…”
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Closed network growth of fullerenes
Published in Nature communications (22-05-2012)“…Tremendous advances in nanoscience have been made since the discovery of the fullerenes; however, the formation of these carbon-caged nanomaterials still…”
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Electrically Compensated Fourier Transform Ion Cyclotron Resonance Cell for Complex Mixture Mass Analysis
Published in Analytical chemistry (Washington) (01-09-2011)“…Complex natural organic mixtures such as petroleum require ultrahigh mass spectral resolution to separate and identify thousands of elemental compositions…”
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Collision Cross Section Measurements for Biomolecules within a High-Resolution Fourier Transform Ion Cyclotron Resonance Cell
Published in Analytical chemistry (Washington) (21-04-2015)“…To understand the role and function of a biomolecule in a biosystem, it is important to know both its composition and structure. Here, a mass spectrometric…”
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