Search Results - "Kairavi Shah"

Focused ultrasound-mediated drug delivery through the blood-brain barrier by Burgess, Alison, Shah, Kairavi, Hough, Olivia, Hynynen, Kullervo

“…Despite recent advances in blood-brain barrier (BBB) research, it remains a significant hurdle for the pharmaceutical treatment of brain diseases. Focused…”
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Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability by Mooney, Skyler J, Shah, Kairavi, Yeung, Sharon, Burgess, Alison, Aubert, Isabelle, Hynynen, Kullervo

“…Transcranial focused ultrasound technology used to transiently open the blood-brain barrier, is capable of stimulating hippocampal neurogenesis; however, it is…”
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Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery by Weber-Adrian, Danielle, Kofoed, Rikke Hahn, Silburt, Joseph, Noroozian, Zeinab, Shah, Kairavi, Burgess, Alison, Rideout, Shawna, Kügler, Sebastian, Hynynen, Kullervo, Aubert, Isabelle

“…Non-surgical gene delivery to the brain can be achieved following intravenous injection of viral vectors coupled with transcranial MRI-guided focused…”
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Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease by Poon, Charissa T., Shah, Kairavi, Lin, Chiungting, Tse, Ryan, Kim, Kate K., Mooney, Skyler, Aubert, Isabelle, Stefanovic, Bojana, Hynynen, Kullervo

“…Previous studies have demonstrated that temporarily increasing the permeability of the blood-brain barrier using focused ultrasound can reduce β-amyloid plaque…”
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EFFECT OF REPEATED FOCUSED ULTRASOUND TREATMENTS ON THE DAILY LIVING ACTIVITIES OF THE TGCRND8 MOUSE MODEL OF ALZHEIMER'S DISEASE by Poon, Charissa, Shah, Kairavi, Hynynen, Kullervo

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P1‐090: EFFECT OF REPEATED FOCUSED ULTRASOUND TREATMENTS ON THE DAILY LIVING ACTIVITIES OF THE TGCRND8 MOUSE MODEL OF ALZHEIMER'S DISEASE by Poon, Charissa, Shah, Kairavi, Hynynen, Kullervo

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Neuronal Differentiation of Cartilage-Derived Stem Cells In Vitro and Their Delivery to the Spinal Cord in a Mouse Model of ALS Using MRI-Guided Focused Ultrasound by Shah, Kairavi Ajaykumar

“…Amyotrophic Lateral Sclerosis (ALS) is an incurable neurodegenerative disorder for which stem cells are attractive therapeutic interventions. However, the…”
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NEURON-SPECIFIC TRANSGENE DELIVERY TO THE BRAIN USING MRI-GUIDED FOCUSED ULTRASOUND by Weber-Adrian, Danielle, Noroozian, Zeinab, Silburt, Joseph, Shah, Kairavi, Burgess, Alison, Kügler, Sebastian, Hynynen, Kullervo, Aubert, Isabelle

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P2‐247: Neuron‐Specific Transgene Delivery to the Brain using MRI‐Guided Focused Ultrasound by Weber-Adrian, Danielle, Noroozian, Zeinab, Silburt, Joseph, Shah, Kairavi, Burgess, Alison, Kügler, Sebastian, Hynynen, Kullervo, Aubert, Isabelle

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Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1 2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery by Danielle Weber-Adrian, Rikke Hahn Kofoed, Joseph Silburt, Zeinab Noroozian, Kairavi Shah, Alison Burgess, Shawna Rideout, Sebastian Kügler, Kullervo Hynynen, Isabelle Aubert

“…Abstract Non-surgical gene delivery to the brain can be achieved following intravenous injection of viral vectors coupled with transcranial MRI-guided focused…”
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