Search Results - "Kainkaryam, Raghunandan M"

A gene regulatory network for root epidermis cell differentiation in Arabidopsis by Bruex, Angela, Kainkaryam, Raghunandan M, Wieckowski, Yana, Kang, Yeon Hee, Bernhardt, Christine, Xia, Yang, Zheng, Xiaohua, Wang, Jean Y, Lee, Myeong Min, Benfey, Philip, Woolf, Peter J, Schiefelbein, John

“…The root epidermis of Arabidopsis provides an exceptional model for studying the molecular basis of cell fate and differentiation. To obtain a systems-level…”
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poolMC: smart pooling of mRNA samples in microarray experiments by Kainkaryam, Raghunandan M, Bruex, Angela, Gilbert, Anna C, Schiefelbein, John, Woolf, Peter J

“…Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a…”
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poolHiTS: a shifted transversal design based pooling strategy for high-throughput drug screening by Kainkaryam, Raghunandan M, Woolf, Peter J

“…A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in…”
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Use of connectivity mapping to support read across: A deeper dive using data from 186 chemicals, 19 cell lines and 2 case studies by De Abrew, K. Nadira, Shan, Yuqing K., Wang, Xiaohong, Krailler, Jesse M., Kainkaryam, Raghunandan M., Lester, Cathy C., Settivari, Raja S., LeBaron, Matthew J., Naciff, Jorge M., Daston, George P.

“…We previously demonstrated that the Connectivity Map (CMap) (Lamb et al., 2006) concept can be successfully applied to a predictive toxicology paradigm to…”
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Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping by De Abrew, K Nadira, Kainkaryam, Raghunandan M, Shan, Yuqing K, Overmann, Gary J, Settivari, Raja S, Wang, Xiaohong, Xu, Jun, Adams, Rachel L, Tiesman, Jay P, Carney, Edward W, Naciff, Jorge M, Daston, George P

“…Connectivity mapping is a method used in the pharmaceutical industry to find connections between small molecules, disease states, and genes. The concept can be…”
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Tissue-Specific Profiling Reveals Transcriptome Alterations in Arabidopsis Mutants Lacking Morphological Phenotypes by Simon, Marissa, Bruex, Angela, Kainkaryam, Raghunandan M., Zheng, Xiaohua, Huang, Ling, Woolf, Peter J., Schiefelbein, John

“…Traditional genetic analysis relies on mutants with observable phenotypes. Mutants lacking visible abnormalities may nevertheless exhibit molecular differences…”
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Smart pooling of mRNA samples for efficient transcript profiling by Kainkaryam, Raghunandan M, Bruex, Angela, Woolf, Peter J, Schiefelbein, John

“…Gene expression profiling studies are commonly used to study signaling pathways and their impact on transcriptional regulation in plants. In some cases, a…”
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Pooling in high-throughput drug screening by Kainkaryam, Raghunandan M, Woolf, Peter J

“…Pooling in HTS refers to the act of testing mixtures of compounds in a primary screen to accurately identify hits for secondary screening. The reduction in the…”
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Pooling designs for high-throughput biological experiments by Kainkaryam, Raghunandan M

“…High-throughput experiments provide a fast, automated way to obtain massive amounts of information about biological systems. In several instances, these…”
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Pooling designs for high-throughput biological experiments by Kainkaryam, Raghunandan M

“…High-throughput experiments provide a fast, automated way to obtain massive amounts of information about biological systems. In several instances, these…”
Get full text