Search Results - "Kaibuchi, K"

REGULATION OF THE CYTOSKELETON AND CELL ADHESION BY THE RHO FAMILY GTPASES IN MAMMALIAN CELLS by Kaibuchi, K, Kuroda, S, Amano, M

“…Members of the Rho family of small Ras-like GTPases-including RhoA, -B, and -C, Rac1 and -2, and Cdc42-exhibit guanine nucleotide-binding activity and function…”
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Regulation of microtubules in cell migration by Watanabe, Takashi, Noritake, Jun, Kaibuchi, Kozo

“…Directional cell migration is a fundamental process in all organisms that is stringently regulated during tissue development, chemotaxis and wound healing…”
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Repetitive and compulsive‐like behaviors lead to cognitive dysfunction in Disc1Δ2‐3/Δ2‐3 mice by Wulaer, B., Nagai, T., Sobue, A., Itoh, N., Kuroda, K., Kaibuchi, K., Nabeshima, T., Yamada, K.

“…Disrupted‐in‐schizophrenia 1 (Disc1) is a key molecular driver for the biology of mental diseases. In order to investigate its role in brain function, we…”
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CRMP-2 binds to tubulin heterodimers to promote microtubule assembly by Kaibuchi, Kozo, Fukata, Yuko, Itoh, Tomohiko J, Kimura, Toshihide, Ménager, Céline, Nishimura, Takashi, Shiromizu, Takashi, Watanabe, Hiroyasu, Inagaki, Naoyuki, Iwamatsu, Akihiro, Hotani, Hirokazu

“…Regulated increase in the formation of microtubule arrays is thought to be important for axonal growth. Collapsin response mediator protein-2 (CRMP-2) is a…”
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Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival by Jaillard, C, Harrison, S, Stankoff, B, Aigrot, M. S, Calver, A. R, Duddy, G, Walsh, F. S, Pangalos, M. N, Arimura, N, Kaibuchi, K, Zalc, B, Lubetzki, C

“…Endothelial differentiation gene (Edg) proteins are G-protein-coupled receptors activated by lysophospholipid mediators: sphingosine-1-phosphate (S1P) or…”
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CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth by Kaibuchi, Kozo, Nishimura, Takashi, Fukata, Yuko, Kato, Katsuhiro, Yamaguchi, Tomoya, Matsuura, Yoshiharu, Kamiguchi, Hiroyuki

“…Axon growth during neural development is highly dependent on both cytoskeletal re-organization and polarized membrane trafficking. Previously, we demonstrated…”
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Lipodystrophia centrifugalis abdominalis infantilis accompanied by idiopathic encephalopathy by Kaibuchi-Noda, K., Sugiura, K., Akiyama, M.

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Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho by Matsui, T., Amano, M., Yamamoto, T., Chihara, K., Nakafuku, M., Ito, M., Nakano, T., Okawa, K., Iwamatsu, A., Kaibuchi, K.

“…The small GTP binding protein Rho is implicated in cytoskeletal responses to extracellular signals such as lysophosphatidic acid to form stress fibers and…”
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Sexually dimorphic expression of Usp9x is related to sex chromosome complement in adult mouse brain by Xu, J., Taya, S., Kaibuchi, K., Arnold, A. P.

“…We found the expression of Usp9x, an X‐linked gene which encodes a ubiquitin protease implicated in synaptic development, to be significantly higher in the…”
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Synaptic development is controlled in the periactive zones of Drosophila synapses by Sone, M, Suzuki, E, Hoshino, M, Hou, D, Kuromi, H, Fukata, M, Kuroda, S, Kaibuchi, K, Nabeshima, Y, Hama, C

“…A cell-adhesion molecule fasciclin 2 (FAS2), which is required for synaptic growth and still life (SIF), an activator of RAC, were found to localize in the…”
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Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins by Ullrich, O., Stenmark, H., Alexandrov, K., Huber, L.A., Kaibuchi, K., Sasaki, T., Takai, Y., Zerial, M.

“…Rab proteins comprise a family of small GTPases that serve a regulatory role in membrane traffic. These proteins are in part cytosolic and in part associated…”
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Evidence that many of the DISC1 isoforms in C57BL 6J mice are also expressed in 129S6 SvEv mice by Ishizuka, K, Chen, J, Taya, S, Li, W, Millar, J K, Xu, Y, Clapcote, S J, Hookway, C, Morita, M, Kamiya, A, Tomoda, T, Lipska, B K, Roder, J C, Pletnikov, M, Porteous, D, Silva, A J, Cannon, T D, Kaibuchi, K, Brandon, N J, Weinberger, D R, Sawa, A

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Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system by Torii, M a, Matsuzaki, F, Osumi, N, Kaibuchi, K, Nakamura, S, Casarosa, S, Guillemot, F, Nakafuku, M

“…Like other tissues and organs in vertebrates, multipotential stem cells serve as the origin of diverse cell types during genesis of the mammalian central…”
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Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin by SHIRATAKI, H, KAIBUCHI, K, SAKODA, T, KISHIDA, S, YAMAGUCHI, T, WADA, K, MIYAZAKI, M, TAKAI, Y

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Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G by Gotoh, Takaya, Hattori, Seisuke, Nakamura, Shun, Kitayama, Hitoshi, Noda, Makoto, Takai, Yoshimi, Kaibuchi, Kozo, Matsui, Hideki, Hatase, Osamu, Takahashi, Hidehiro, Kurata, Takeshi, Matsuda, Michiyuki

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Involvement of Rho-kinase in hypertensive vascular disease: a novel therapeutic target in hypertension by Mukai, Y, Shimokawa, H, Matoba, T, Kandabashi, T, Satoh, S, Hiroki, J, Kaibuchi, K, Takeshita, A

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Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction by HIRATA, K.-I, KIKUCHI, A, SASAKI, T, KURODA, S, KAIBUCHI, K, MATSUURA, Y, SEKI, H, SAIDA, K, TAKAI, Y

“…In the rabbit mesenteric arterial smooth muscle skinned by saponin, Ca2+ induced contraction in a concentration-dependent manner. Guanosine…”
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Ras-Induced Transformation and Signaling Pathway by Yamamoto, Takaharu, Taya, Shinichiro, Kaibuchi, Kozo

“…Ras is a signal-transducing, guanine nucleotide-binding protein for various membrane receptors including tyrosine kinase receptors. Ras participates in the…”
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Numb Controls Integrin Endocytosis for Directional Cell Migration with aPKC and PAR-3 by Nishimura, Takashi, Kaibuchi, Kozo

“…Migrating cells extend protrusions to establish new adhesion sites at their leading edges. One of the driving forces for cell migration is the directional…”
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The Insert Region of RhoA Is Essential for Rho Kinase Activation and Cellular Transformation by Zong, Hui, Kaibuchi, Kozo, Quilliam, Lawrence A.

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