Search Results - "Kai, Yasuyuki"

The effect of Clostridium butyricum MIYAIRI on the prevention of pouchitis and alteration of the microbiota profile in patients with ulcerative colitis by Yasueda, Asuka, Mizushima, Tsunekazu, Nezu, Riichiro, Sumi, Ryoko, Tanaka, Mamoru, Nishimura, Junichi, Kai, Yasuyuki, Hirota, Masaki, Osawa, Hideki, Nakajima, Kiyokazu, Mori, Masaki, Ito, Toshinori

“…Purpose Ulcerative colitis (UC) is a chronic, relapsing, and refractory disorder of the intestine. Total proctocolectomy with ileal pouch anal anastomosis…”
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Therapeutic effects of novel sphingosine-1-phosphate receptor agonist W-061 in murine DSS colitis by Sanada, Yasuaki, Mizushima, Tsunekazu, Kai, Yasuyuki, Nishimura, Junichi, Hagiya, Hiroshi, Kurata, Haruto, Mizuno, Hirotaka, Uejima, Etsuko, Ito, Toshinori

“…Although IL-17 is a pro-inflammatory cytokine reportedly involved in various autoimmune inflammatory disorders, its role remains unclear in murine models of…”
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A novel sphingosine 1-phosphate receptor agonist, 2-amino-2-propanediol hydrochloride (KRP-203), regulates chronic colitis in interleukin-10 gene-deficient mice by Song, Jinghai, Matsuda, Chu, Kai, Yasuyuki, Nishida, Toshirou, Nakajima, Kiyokazu, Mizushima, Tsunekazu, Kinoshita, Miki, Yasue, Tokutaro, Sawa, Yoshiki, Ito, Toshinori

“…Current treatments for patients with Crohn's disease (CD) are based on recent advances in elucidating the pathophysiology of the disease. A satisfactory…”
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Malignancy in Crohn's disease: incidence and clinical characteristics in Japan by Mizushima, Tsunekazu, Ohno, Yuko, Nakajima, Kiyokazu, Kai, Yasuyuki, Iijima, Hideki, Sekimoto, Mitsugu, Nishida, Toshirou, Nezu, Riichiro, Ito, Toshinori, Doki, Yuichiro, Mori, Masaki

“…This study investigated the occurrence of malignancies in Japanese patients with Crohn's disease (CD) and compared the incidence with that in the general…”
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A simple application technique of fibrin-coated collagen fleece (TachoComb) in laparoscopic surgery by Nakajima, Kiyokazu, Yasumasa, Keigo, Endo, Shunji, Takahashi, Tsuyoshi, Kai, Yasuyuki, Nezu, Riichiro, Nishida, Toshirou

“…A fibrin-coated collagen fleece (TachoComb, Nycomed, Denmark) is a powerful topical hemostatic agent, which has been aggressively used in conventional open…”
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A Practical Online Error Detection Method for Functional Safety Using Three-Site Implications by Loki, Kazuya, Kai, Yasuyuki, Miyase, Kohei, Kajihara, Seiji

“…In this paper, we propose a practical error detection method for combinatorial circuits using three-site implications which satisfies safety integrity level…”
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Three cases of colorectal cancer in patients with Crohn's disease by Mizushima, Tsunekazu, Nezu, Riichiro, Ito, Toshinori, Uchikoshi, Fumihiro, Kai, Yasuyuki, Tamagawa, Hiroshi, Matsuda, Chu, Yamagami, Yuko, Inoue, Yoshifumi, Matsuda, Hikaru

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A Case of Breast Cancer Coexisting with Florid Papillomatosis of the Nipple by Ono, M, Yoshikawa, K, Yamaguchi, T, Dosei, T, Tominaga, H, Kai, Y, Kawano, K, Tsujimura, T

“…We report a 47 year-old woman with a unique breast cancer coexisting with florid papillomatosis (FP) of the left nipple. The diseased nipple was enlarged and…”
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Therapeutic effects of a new lymphocyte homing reagent FTY720 in interleukin‐10 gene‐deficient mice with colitis by Mizushima, Tsunekazu, Ito, Toshinori, Kishi, Daisuke, Kai, Yasuyuki, Tamagawa, Hiroshi, Nezu, Riichiro, Kiyono, Hiroshi, Matsuda, Hikaru

“…Background: FTY720 is a novel reagent that possesses potent immunosuppressive activity. The immunosuppression induced by FTY720 is mediated by completely…”
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Colitis in mice lacking the common cytokine receptor γ chain is mediated by IL-6-producing CD4 + T cells by Kai, Yasuyuki, Takahashi, Ichiro, Ishikawa, Hiromichi, Hiroi, Takachika, Mizushima, Tsunekazu, Matsuda, Chu, Kishi, Daisuke, Hamada, Hiromasa, Tamagawa, Hiroshi, Ito, Toshinori, Yoshizaki, Kazuyuki, Kishimoto, Tadamitsu, Matsuda, Hikaru, Kiyono, Hiroshi

“…Background & Aims: Mice that have a truncated mutation of the common cytokine receptor γ chain (CRγ −/Y) are known to spontaneously develop colitis. To…”
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Alteration of Vβ Usage and Cytokine Production of CD4+ TCR ββ Homodimer T Cells by Elimination of Bacteroides vulgatus Prevents Colitis in TCR α-Chain-Deficient Mice by Kishi, Daisuke, Takahashi, Ichiro, Kai, Yasuyuki, Tamagawa, Hiroshi, Iijima, Hideki, Obunai, Suguru, Nezu, Riichiro, Ito, Toshinori, Matsuda, Hikaru, Kiyono, Hiroshi

“…A major pathogenic factor for the development of inflammatory bowel disease (IBD) is the breakdown of the intestinal homeostasis between the host immune system…”
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Complementary Medicine & Mucosal Immunology: Recent Topics around Inflammatory Bowel Disease by ITO, Toshinori, KAI, Yasuyuki, IGURA, Takumi, NAKAJIMA, Seiichi, NISHIDA, Toshiro, MIZUSHIMA, Tsunekazu, NEZU, Riichiro

“…Complementary medicine aimed at improving patients’ QOL by complementing modern medicine has recently become the focus of attention. These alternative…”
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Development of colitis in signal transducers and activators of transcription 6-deficient T-cell receptor α-deficient mice: A potential role of signal transducers and activators of transcription 6-independent interleukin-4 signaling for the generation of th2-biased pathological CD4+ ββT cells by OKUDA, Yoshiko, TAKAHASHI, Ichiro, KAWANO, Sunao, TAKEDA, Kiyoshi, AKIRA, Sizuo, SASAKI, Yutaka, HORI, Masatsugu, KIYONO, Hiroshi, KIM, Jin-Kyung, OHTA, Noriyuki, IWATANI, Kouichi, IIJIMA, Hideki, KAI, Yasuyuki, TAMAGAWA, Hiroshi, HIROI, Takachika, KWEON, Mi-Na

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Subcutaneous emphysema along cutaneous striae after laparoscopic surgery: a unique complication by Nakajima, Kiyokazu, Kai, Yasuyuki, Yasumasa, Keigo, Nishida, Toshirou, Ito, Toshinori, Nezu, Riichiro

“…A case of postlaparoscopic subcutaneous emphysema developed along cutaneous striae was reported. A 35-year-old male patient with marked cutaneous striae…”
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Development of Colitis in Signal Transducers and Activators of Transcription 6-Deficient T-Cell Receptor α-Deficient Mice: A Potential Role of Signal Transducers and Activators of Transcription 6-Independent Interleukin-4 Signaling for the Generation of Th2-Biased Pathological CD4 by Okuda, Yoshiko, Takahashi, Ichiro, Kim, Jin-Kyung, Ohta, Noriyuki, Iwatani, Kouichi, Iijima, Hideki, Kai, Yasuyuki, Tamagawa, Hiroshi, Hiroi, Takachika, Kweon, Mi-Na, Kawano, Sunao, Takeda, Kiyoshi, Akira, Sizuo, Sasaki, Yutaka, Hori, Masatsugu, Kiyono, Hiroshi

“…Forbidden CD4 + ββ T cells, which produce interleukin (IL)-4 predominantly, are a pathological subset in the development of colitis in T-cell receptor α chain…”
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Development of Colitis in Signal Transducers and Activators of Transcription 6-Deficient T-Cell Receptor α-Deficient Mice by Okuda, Yoshiko, Takahashi, Ichiro, Kim, Jin-Kyung, Ohta, Noriyuki, Iwatani, Kouichi, Iijima, Hideki, Kai, Yasuyuki, Tamagawa, Hiroshi, Hiroi, Takachika, Kweon, Mi-Na, Kawano, Sunao, Takeda, Kiyoshi, Akira, Sizuo, Sasaki, Yutaka, Hori, Masatsugu, Kiyono, Hiroshi

“…Forbidden CD4 +ββ T cells, which produce interleukin (IL)-4 predominantly, are a pathological subset in the development of colitis in T-cell receptor α chain…”
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Development of colitis in signal transducers and activators of transcription 6-deficient T-cell receptor alpha-deficient mice: a potential role of signal transducers and activators of transcription 6-independent interleukin-4 signaling for the generation of Th2-biased pathological CD4+ betabetaT cells by Okuda, Yoshiko, Takahashi, Ichiro, Kim, Jin-Kyung, Ohta, Noriyuki, Iwatani, Kouichi, Iijima, Hideki, Kai, Yasuyuki, Tamagawa, Hiroshi, Hiroi, Takachika, Kweon, Mi-Na, Kawano, Sunao, Takeda, Kiyoshi, Akira, Sizuo, Sasaki, Yutaka, Hori, Masatsugu, Kiyono, Hiroshi

“…Forbidden CD4(+)betabeta T cells, which produce interleukin (IL)-4 predominantly, are a pathological subset in the development of colitis in T-cell receptor…”
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Colitis-Related Public T Cells Are Selected in the Colonic Lamina Propria of IL-10-Deficient Mice by Takahashi, Ichiro, Matsuda, Jennifer, Gapin, Laurent, DeWinter, Hilde, Kai, Yasuyuki, Tamagawa, Hiroshi, Kronenberg, Mitchell, Kiyono, Hiroshi

“…IL-10 is an important regulatory cytokine in the mucosal immune system, as supported by the fact that mice deficient in IL-10 spontaneously develop Crohn's…”
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Colitis-related public T cells are selected in the colonic lamina propria of IL-10-deficient mice by TAKAHASHI, Ichiro, MATSUDA, Jennifer, GAPIN, Laurent, DEWINTER, Hilde, KAI, Yasuyuki, TAMAGAWA, Hiroshi, KRONENBERG, Mitchell, KIYONO, Hiroshi

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Influence of enterotoxin on mucosal intranet: selective inhibition of extrathymic T cell development in intestinal intraepithelial lymphocytes by oral exposure to heat‐labile toxin by Kim, Jin‐Kyung, Takahashi, Ichiro, Kai, Yasuyuki, Kiyono, Hiroshi

“…We tested the possibility that heat‐labile enterotoxin of Escherichia coli (LT) affects the development of extrathymic T cells in the intraepithelial…”
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