Search Results - "Kahnt, Astrid Stefanie"

On the biosynthesis of specialized pro-resolving mediators in human neutrophils and the influence of cell integrity by Mainka, Malwina, George, Sven, Angioni, Carlo, Ebert, Roland, Goebel, Tamara, Kampschulte, Nadja, Krommes, Andre, Weigert, Andreas, Thomas, Dominique, Schebb, Nils Helge, Steinhilber, Dieter, Kahnt, Astrid Stefanie

“…Neutrophils are key players in inflammation initiation and resolution. Little attention has been paid to the detailed biosynthesis of specialized pro-resolving…”
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Lipoxin and resolvin biosynthesis is dependent on 5‐lipoxygenase activating protein by Lehmann, Christoph, Homann, Julia, Ball, Ann‐Katrin, Blöcher, Rene, Kleinschmidt, Thea K., Basavarajappa, Devaraj, Angioni, Carlo, Ferreirós, Nerea, Häfner, Ann‐Kathrin, Rådmark, Olof, Proschak, Ewgenij, Haeggström, Jesper Z., Geisslinger, Gerd, Parnham, Michael J., Steinhilber, Dieter, Kahnt, Astrid Stefanie

“…ABSTRACT Resolution of acute inflammation is an active process coordinated by proresolving lipid mediators (SPMs) such as lipoxins (LXs) and resolvins (Rvs),…”
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AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3 by Ahmad, Khalil, Scholz, Bastian, Capelo, Ricardo, Schweighöfer, Ilona, Kahnt, Astrid Stefanie, Marschalek, Rolf, Steinhilber, Dieter

“…The human 5-lipoxygenase (5-LO), encoded by the ALOX5 gene, is the key enzyme in the formation of pro-inflammatory leukotrienes. ALOX5 gene transcription is…”
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Cysteinyl leukotriene-receptor-1 antagonists interfere with PGE2 synthesis by inhibiting mPGES-1 activity by Kahnt, Astrid Stefanie, Rörsch, Florian, Diehl, Olaf, Hofmann, Bettina, Lehmann, Christoph, Steinbrink, Svenja Dorothea, Angioni, Carlo, Geisslinger, Gerd, Grösch, Sabine, Steinhilber, Dieter, Maier, Thorsten Jürgen

“…Because of their favourable safety profile and beneficial anti-inflammatory properties, the CysLT1 receptor antagonists (LTRA), montelukast, zafirlukast and…”
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