Search Results - "Kahn, Harriette J."

A New Monoclonal Antibody, D2-40, for Detection of Lymphatic Invasion in Primary Tumors by Kahn, Harriette J, Marks, Alexander

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Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer by Arnaout-Alkarain, Angel, Kahn, Harriette J, Narod, Steven A, Sun, Ping A, Marks, Alexander N

“…Monoclonal antibody D2-40, a marker of lymphatic endothelium, identifies tumor emboli in lymph vessels. The aim of the study was to assess whether D2-40+ lymph…”
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Intratumoral heterogeneity of HER2/neu in breast cancer--a rare event by Hanna, Wedad, Nofech-Mozes, Sharon, Kahn, Harriette J

“…HER2/neu is overexpressed in about 20% of invasive breast carcinomas. Numerous studies have shown that there is high level of concordance between the HER2/neu…”
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Monoclonal Antibody D2-40, a New Marker of Lymphatic Endothelium, Reacts with Kaposi's Sarcoma and a Subset of Angiosarcomas by Kahn, Harriette J, Bailey, Denis, Marks, Alexander

“…There is controversy over the histogenesis of Kaposi's sarcoma (KS) from lymphatic or blood vessel endothelium. D2-40 is a novel monoclonal antibody to an Mr…”
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Loss of androgen receptor associated protein 70 (ARA70) expression in a subset of HER2-positive breast cancers by KOLLARA, Alexandra, KAHN, Harriette J, MARKS, Alexander, BROWN, Theodore J

“…Co-transfection studies indicate that HER2 (erbB-2) overexpression results in the phosphorylation and enhanced transcriptional activity of the androgen…”
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Biological Markers Predictive of Invasive Recurrence in DCIS by Nofech-Mozes, Sharon, Spayne, Jacqueline, Rakovitch, Eileen, Kahn, Harriette J, Seth, Arun, Pignol, Jean-Phillippe, Lickley, Lavina, Paszat, Lawrence, Hanna, Wedad

“…DCIS is a heterogeneous group of non-invasive cancers of the breast characterized by various degrees of differentiation and unpredictable propensity for…”
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Breast metastasis by medullary thyroid carcinoma detected by FDG positron emission tomography by Nofech-Mozes, Sharon, MD, Mackenzie, Robert, MD, FRCPC, Kahn, Harriette J., MD, FRCPC, Ehrlich, Lisa, MD, FRCPC, Raphael, Simon J., MD, FRCPC

“…Abstract Medullary thyroid carcinoma (MTC) is an uncommon thyroid cancer comprising 5% to 8% of thyroid neoplasms. In contrast to common thyroid tumors, this…”
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Imaging of HER2/neu-positive BT-474 human breast cancer xenografts in athymic mice using (111)In-trastuzumab (Herceptin) Fab fragments by Tang, Ying, Wang, Judy, Scollard, Deborah A, Mondal, Hridya, Holloway, Claire, Kahn, Harriette J, Reilly, Raymond M

“…Trastuzumab (Herceptin) Fab were prepared by digestion of intact IgG with immobilized papain, derivatized with diethylenetriaminepentaacetic acid (DTPA) and…”
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Analysis of the HER2/neu Gene Amplification in Microdissected Breast Cancer Tumour Samples by SETH, Rishie M, BURGER, Angelika M, KAHN, Harriette J

“…The HER2/neu oncogene has been reported to be amplified in >20% of invasive ductal carcinomas. In order to investigate the HER2/neu status in pure populations…”
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Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients by NAN SOON WONG, KAHN, Harriette J, LIYING ZHANG, OLDFIELD, Stephanie, YANG, Lu-Ying, MARKS, Alexander, TRUDEAU, Maureen E

“…We previously found a higher incidence of circulating tumour cells (CTCs) in women with metastatic breast cancer compared to early disease. In this study, we…”
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A novel RING-type ubiquitin ligase Breast Cancer-Associated Gene 2 correlates with outcome in invasive breast cancer by BURGER, Angelika M, YUGUANG GAO, AMEMIYA, Yutaka, KAHN, Harriette J, KITCHING, Richard, YILI YANG, PING SUN, NAROD, Steven A, HANNA, Wedad M, SETH, Arun K

“…The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. In this…”
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Enumeration of circulating tumor cells in the blood of breast cancer patients after filtration enrichment: correlation with disease stage by KAHN, Harriette J, PRESTA, Anthony, YANG, Lu-Ying, BLONDAL, John, TRUDEAU, Maureen, LICKLEY, Lavina, HOLLOWAY, Claire, MCCREADY, David R, MACLEAN, Daniel, MARKS, Alexander

“…The biological and clinical significance of circulating tumor cells (CTC) in the peripheral blood of breast cancer patients is not known. To study this…”
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D2-40 is Expressed on the Luminal Surface of Pulmonary Airspaces in Normal Developing and Adult Lung but is Lost in Conditions Associated with Intra-Alveolar Infiltrates by Sherman, Christopher G., Jani, Prashant, Marks, Alexander, Kahn, Harriette J.

“…The D2-40 antigen is a glycosylated sialomucin that is strongly expressed by lymphatic endothelial cells. Recently we observed the expression of D2-40 on the…”
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Phase I trial of intraoperative detection of tumor margins in patients with HER2-positive carcinoma of the breast following administration of 111In-DTPA-trastuzumab Fab fragments by Holloway, Claire M.B., Scollard, Deborah A., Caldwell, Curtis B., Ehrlich, Lisa, Kahn, Harriette J., Reilly, Raymond M.

“…Our aim was to conduct a Phase I clinical trial to determine the feasibility of intraoperative detection of tumor margins in HER2 positive breast carcinoma…”
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Association of low tumor RNA integrity with response to chemotherapy in breast cancer patients by Parissenti, Amadeo M, Chapman, Judy-Anne W, Kahn, Harriette J, Guo, Baoqing, Han, Lei, O'Brien, Patti, Clemons, Mark P, Jong, Roberta, Dent, Rebecca, Fitzgerald, Barbara, Pritchard, Kathleen I, Shepherd, Lois E, Trudeau, Maureen E

“…The CAN-NCIC-MA22 phase I/II clinical trial evaluated women with locally advanced or inflammatory breast cancer treated with epirubicin and docetaxel at 2 or 3…”
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A phase I/II trial of epirubicin and docetaxel in locally advanced breast cancer (LABC) on 2-weekly or 3-weekly schedules: NCIC CTG MA.22 by Trudeau, Maureen Elizabeth, Chapman, Judith-Anne W., Guo, Baoqing, Clemons, Mark J., Dent, Rebecca A., Jong, Roberta A., Kahn, Harriette J., Pritchard, Kathleen I., Han, Lei, O’Brien, Patti, Shepherd, Lois E., Parissenti, Amadeo M.

“…This phase I/II neoadjuvant trial (ClinicalTrials.gov identifier NCT00066443) determined maximally-tolerated doses (MTD), dose-limiting toxicities,…”
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Breast cancer metastasis in a human bone NOD/SCID mouse model by Yang, Wenyi, Lam, Pearl, Kitching, Richard, Kahn, Harriette J, Yee, Albert, Aubin, Jane E, Seth, Arun

“…A major dilemma facing patients with breast cancer is how to decide between over treating indolent tumors and failing to adequately treat aggressive,…”
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Biological significance of occult micrometastases in histologically negative axillary lymph nodes in breast cancer patients using the recent American Joint Committee on Cancer breast cancer staging system by Kahn, Harriette J, Hanna, Wedad M, Chapman, Judy-Anne W, Trudeau, Maureen E, Lickley, H Lavina A, Mobbs, Betty G, Murray, David, Pritchard, Kathleen I, Sawka, Carol A, McCready, David R, Marks, Alexander

“…The biological significance of occult metastases in axillary lymph nodes of breast cancer patients is controversial. The purpose of the study was to determine…”
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Prognostic factors affecting the natural history of node-negative breast cancer by TRUDEAU, Maureen E, PRITCHARD, Kathleen I, LICKLEY, H. Lavina, CHAPMAN, Judy-Anne W, HANNA, Wedad M, KAHN, Harriette J, MURRAY, David, SAWKA, Carol A, MOBBS, Betty G, ANDRULIS, Irene, MCCREADY, David R

“…We undertook a natural history investigation of a broad selection of prognostic factors in a cohort of women with node-negative breast cancer. The cohort…”
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Tenascin differentiates dermatofibroma from dermatofibrosarcoma protuberans: Comparison with CD34 and factor XIIIa by Kahn, Harriette J., Fekete, Eva, From, Lynn

“…Differentiation of dermatofibroma (DF) from dermatofibrosarcoma protuberans (DFSP) can be difficult. CD34 and Factor XIIIa have been used to differentiate DF…”
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