Search Results - "Kahn, B. B."

Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids by Smith, U., Kahn, B. B.

“…Obesity, the major cause of the current global epidemic of type 2 diabetes (T2D), induces insulin resistance in peripheral insulin target tissues. Several…”
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Do recessions accelerate routine-biased technological change?: Evidence from vacancy postings by Hershbein, Brad J, Kahn, Lisa B

“…We show that skill requirements in job vacancy postings differentially increased in MSAs that were hit hard by the Great Recession, relative to less hard-hit…”
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Labor demand in the time of COVID-19: Evidence from vacancy postings and UI claims by Forsythe, Eliza, Kahn, Lisa B., Lange, Fabian, Wiczer, David

“…We use job vacancy data collected in real time by Burning Glass Technologies, as well as unemployment insurance (UI) initial claims and the more traditional…”
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Adipose Tissue, Inter-Organ Communication, and the Path to Type 2 Diabetes: The 2016 Banting Medal for Scientific Achievement Lecture by Kahn, Barbara B

“…My scientific career has focused on understanding the mechanisms underlying insulin resistance with the goal of developing new strategies to prevent and treat…”
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The long-term labor market consequences of graduating from college in a bad economy by Kahn, Lisa B

“…This paper studies the labor market experiences of white-male college graduates as a function of economic conditions at time of college graduation. I use the…”
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Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects by Yore, Mark M., Syed, Ismail, Moraes-Vieira, Pedro M., Zhang, Tejia, Herman, Mark A., Homan, Edwin A., Patel, Rajesh T., Lee, Jennifer, Chen, Shili, Peroni, Odile D., Dhaneshwar, Abha S., Hammarstedt, Ann, Smith, Ulf, McGraw, Timothy E., Saghatelian, Alan, Kahn, Barbara B.

“…Increased adipose tissue lipogenesis is associated with enhanced insulin sensitivity. Mice overexpressing the Glut4 glucose transporter in adipocytes have…”
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Investigating the relationship between innovation strategy and performance by Kahn, Kenneth B., Candi, Marina

“…•Firm size and type of offering moderate the innovation strategy-to-performance relationship.•Dual moderation effects exist as well.•Firm size reflects…”
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AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1 by Wu, Ning, Zheng, Bin, Shaywitz, Adam, Dagon, Yossi, Tower, Christine, Bellinger, Gary, Shen, Che-Hung, Wen, Jennifer, Asara, John, McGraw, Timothy E., Kahn, Barbara B., Cantley, Lewis C.

“…Thioredoxin-interacting protein (TXNIP) is an α-arrestin family protein that is induced in response to glucose elevation. It has been shown to provide a…”
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p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake by Dagon, Yossi, Hur, Elizabeth, Zheng, Bin, Wellenstein, Kerry, Cantley, Lewis C., Kahn, Barbara B.

“…The PI3K-AKT, mTOR-p70S6 kinase and AMPK pathways play distinct and critical roles in metabolic regulation. Each pathway is necessary for leptin's anorexigenic…”
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Cashier or consultant?: Entry labor market conditions, field of study, and career success by Altonji, Joseph G, Kahn, Lisa B, Speer, Jamin D

“…We measure impacts of entry conditions on labor market outcomes for the US college graduating classes of 1974–2011. A large recession reduces initial earnings…”
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Lower limb angular velocity during walking at various speeds by Mentiplay, Benjamin F., Banky, Megan, Clark, Ross A., Kahn, Michelle B., Williams, Gavin

“…•Angular velocity during walking at various speeds in a healthy cohort was examined.•A full dataset of the angular velocities for each walking speed is…”
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Asymmetric information between employers by Kahn, Lisa B

“…This study explores whether potential employers have the same information about worker ability as the incumbent firm. I develop a model of asymmetric learning…”
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Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1 by Yang, Zhenggang, Kahn, Barbara B., Shi, Hang, Xue, Bing-zhong

“…In this study, we aim to determine cellular mechanisms linking nutrient metabolism to the regulation of inflammation and insulin resistance. The nutrient…”
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Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat by Dodd, Garron T., Decherf, Stephanie, Loh, Kim, Simonds, Stephanie E., Wiede, Florian, Balland, Eglantine, Merry, Troy L., Münzberg, Heike, Zhang, Zhong-Yin, Kahn, Barbara B., Neel, Benjamin G., Bence, Kendra K., Andrews, Zane B., Cowley, Michael A., Tiganis, Tony

“…The primary task of white adipose tissue (WAT) is the storage of lipids. However, “beige” adipocytes also exist in WAT. Beige adipocytes burn fat and dissipate…”
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Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin by Kong, Xingxing, Yao, Ting, Zhou, Peng, Kazak, Lawrence, Tenen, Danielle, Lyubetskaya, Anna, Dawes, Brian A., Tsai, Linus, Kahn, Barbara B., Spiegelman, Bruce M., Liu, Tiemin, Rosen, Evan D.

“…Skeletal muscle and brown adipose tissue (BAT) are functionally linked, as exercise increases browning via secretion of myokines. It is unknown whether BAT…”
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A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism by Herman, Mark A., Peroni, Odile D., Villoria, Jorge, Schön, Michael R., Abumrad, Nada A., Blüher, Matthias, Klein, Samuel, Kahn, Barbara B.

“…The prevalence of obesity and type 2 diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a…”
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Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects by Graham, T. E, Wason, C. J, Blüher, M, Kahn, B. B

“…Aims/hypothesis Levels of retinol binding protein (RBP4) are increased in the serum of insulin-resistant human subjects even before overt diabetes develops…”
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AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues by Xue, Bingzhong, Kahn, Barbara B.

“…The evolutionarily conserved serine/threonine kinase, AMP-activated protein kinase (AMPK), functions as a cellular fuel gauge that regulates metabolic pathways…”
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Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism by Norseen, Julie, Hosooka, Tetsuya, Hammarstedt, Ann, Yore, Mark M., Kant, Shashi, Aryal, Pratik, Kiernan, Urban A., Phillips, David A., Maruyama, Hiroshi, Kraus, Bettina J., Usheva, Anny, Davis, Roger J., Smith, Ulf, Kahn, Barbara B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue by Blüher, Matthias, Kahn, Barbara B., Kahn, C. Ronald

“…Caloric restriction has been shown to increase longevity in organisms ranging from yeast to mammals. In some organisms, this has been associated with a…”
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