Search Results - "Kahlert, U."

Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas by Kahlert, U.D, Nikkhah, G, Maciaczyk, J

“…Abstract Tumor dissemination and metastatic behavior account for the vast majority of cancer associated mortality. Epithelial tumors achieve this progressive…”
Get full text

Targeting cancer stem‐like cells in glioblastoma and colorectal cancer through metabolic pathways by Kahlert, U.D., Mooney, S.M., Natsumeda, M., Steiger, H.‐J., Maciaczyk, J.

“…Cancer stem‐like cells (CSCs) are thought to be the main cause of tumor occurrence, progression and therapeutic resistance. Strong research efforts in the last…”
Get full text

CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells by Maciaczyk, D, Picard, D, Zhao, L, Koch, K, Herrera-Rios, D, Li, G, Marquardt, V, Pauck, D, Hoerbelt, T, Zhang, W, Ouwens, D M, Remke, M, Jiang, T, Steiger, H J, Maciaczyk, J, Kahlert, U D

“…Background: Glioblastoma is the most common and most lethal primary brain cancer. CBF1 (also known as Recombination signal Binding Protein for immunoglobulin…”
Get full text

Isoflurane enhances the malignant potential of glioblastoma stem cells by promoting their viability, mobility in vitro and migratory capacity in vivo by Zhu, M, Li, M, Zhou, Y, Dangelmajer, S, Kahlert, U.D., Xie, R, Xi, Q, Shahveranov, A, Ye, D, Lei, T

“…Isoflurane is one of the most common general anaesthetics used during surgical procedures, including tumour resection. However, the effects of isoflurane on…”
Get full text

The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H by Mehjardi, N. Z., Kessler, J., Sanin, A. Y., Picard, D., Westhoff, P., Nickel, Ann-Christin, Uhlmann, C., Shi, W., Steiger, H. J., Remke, M., Fischer, I., Vordermark, D., Croner, R. S., Kahlert, U. D.

“…The application of patient-derived (PD) in vitro tumor models represents the classical strategy for clinical translational oncology research. Using these…”
Get full text

Longitudinal stability of molecular alterations and drug response profiles in tumor spheroid cell lines enables reproducible analyses by Nickel, A.C., Picard, D., Qin, N., Wolter, M., Kaulich, K., Hewera, M., Pauck, D., Marquardt, V., Torga, G., Muhammad, S., Zhang, W., Schnell, O., Steiger, H.-J., Hänggi, D., Fritsche, E., Her, N.-G., Nam, D.-H., Carro, M.S., Remke, M., Reifenberger, G., Kahlert, U.D.

“…The utility of patient-derived tumor cell lines as experimental models for glioblastoma has been challenged by limited representation of the in vivo tumor…”
Get full text

PB2207: IN VITRO VALIDATION OF DENDRIMER‐BASED APPROACH FOR MICRO‐RNA DELIVERY INTO LEUKEMIA CELLS by Knauer, N., Pashkina, E., Boeva, O., Aktanova, A., Arkhipova, V., Meschaninova, M., Gomez, R., Sánchez‐Nieves, J., Nickel, A.‐C., Kahlert, U., Majoral, J.‐P., Kozlov, V., Apartsin, E.

Get full text

Histone Deacetylase 2 (HDAC2) Inhibitors Containing Boron by Kavianpour, Poya, Gemmell, Madeleine C. M., Kahlert, Jan U., Rendina, Louis M.

“…Histone deacetylase enzymes (HDACs) are responsible for the global silencing of tumour‐suppressor genes. Treatment with a histone deacetylase inhibitor (HDACi)…”
Get full text

49P Antitumor effects of cationic dendritic molecules and their complexes with microRNA in glioblastoma stem-like cells by Knauer, N., Pashkina, E., Kozlov, V., Gomez, R., Caminade, A-M., Kahlert, U., Apartsin, E.

Get full text

Postnatal development of hepatocellular apolipoprotein B assembly and secretion in the rat by Plonné, Dietmar, Schulze, Hans-Peter, Kahlert, Ulla, Meltke, Kerstin, Seidolt, Holger, Bennett, Andrew J., Cartwright, Ian J., Higgins, Joan A., Till, Uwe, Dargel, Rolf

“…In this study, we explored the paradox that in suckling rats the serum concentration of LDL is high although the liver secretes only minimal quantities of…”
Get full text

SIOG2022-0191 - Discovering aging associated biomarkers by metabolomic analysis in a small cohort of single-institution study for surgical resectable pancreatic ductal adenocarcinoma (PDAC) patients by Zhao, Y., Fan, N., Acciuffi, S., Wartmann, T., Deelen, J., Link, A., Vargas, R.V., Kahlert, U., Halangk, W., Malfertainer, P., Polidori, M.C., Bruns, C.

Get full text

Discovering aging associated biomarkers by metabolomic analysis in a small cohort of single-institution study for surgical resectable pancreatic ductal adenocarcinoma (PDAC) patients by Zhao, Y., Fan, N., Acciuffi, S., Wartmann, T., Deelen, J., Link, A., Vargas, R.V., Kahlert, U., Halangk, W., Malfertainer, P., Polidori, M.C., Bruns, C.

Get full text

CD133/CD15 defines distinct cell subpopulations with differential in vitro clonogenic activity and stem cell-related gene expression profile in in vitro propagated glioblastoma multiforme-derived cell line with a PNET-like component by Kahlert, Ulf D, Bender, Noemi O, Maciaczyk, Donata, Bogiel, Tomasz, Bar, Eli E, Eberhart, Charles G, Nikkhah, Guido, Maciaczyk, Jarosław

“…Glioblastoma multiforme (GBM), as many other solid tumours, contains a subpopulation of cells termed cancer stem-like cells responsible for the initiation and…”
Get full text

Die junge neuroonkologische Arbeitsgemeinschaft (YoungNOA): Eine Gruppe in der neuroonkologischen Arbeitsgemeinschaft (NOA) der Deutschen Krebsgesellschaft (DKG) by Gepfner-Tuma, I., Lazaridis, L., Bodensohn, R., Tzaridis, T., Kessler, T., Sagerer, A., Behling, F., Kahlert, U., Kebir, S., Berberich, A.

Get full text

Glutaredoxin 2 promotes SP-1-dependent CSPG4 transcription and migration of wound healing NG2 glia and glioma cells: Enzymatic Taoism by Wilms, Christina, Lepka, Klaudia, Häberlein, Felix, Edwards, Steven, Felsberg, Jörg, Pudelko, Linda, Lindenberg, Tobias T., Poschmann, Gereon, Qin, Nan, Volbracht, Katrin, Prozorovski, Tim, Meuth, Sven G., Kahlert, Ulf D., Remke, Marc, Aktas, Orhan, Reifenberger, Guido, Bräutigam, Lars, Odermatt, Benjamin, Berndt, Carsten

“…Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway. Here,…”
Get full text

Current reversal induced by a cyclic stochastic process by Berghaus, Claudia, Kahlert, Uwe, Schnakenberg, Jürgen

“…We consider the mean current for the overdamped motion in a ratchet-like potential driven by a stochastic cyclic three-state force. Approximations for slow and…”
Get full text

Quantitative and qualitative characterization of apolipoprotein B containing lipoproteins produced by the visceral rat yolk sac in two different in vitro systems: organ culture and isolated epithelial cells in suspension culture by Plonné, D, Heller, H, Kahlert, U, Dargel, R

“…Tissue pieces as well as isolated epithelial cells taken from visceral rat yolk sacs at the 18th day of gestation were able to synthesize and to secrete apo B…”
Get more information

Synthesis and reactivity of some alpha-bromoketals (author's transl) by Kahlert, E U, Zymalkowski, F

Get more information