Search Results - "Kahler, H"

Methods for evaluation of medication adherence and persistence using automated databases by Andrade, Susan E., Kahler, Kristijan H., Frech, Feride, Chan, K. Arnold

“…Purpose Our aim was to perform a systematic review of the methods currently being used to assess adherence and persistence in pharmacoepidemiological and…”
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A Questionnaire to Assess the Relevance and Credibility of Observational Studies to Inform Health Care Decision Making: An ISPOR-AMCP-NPC Good Practice Task Force Report by Berger, Marc L., MD, Martin, Bradley C., PharmD, PhD, Husereau, Don, BScPharm, MSc, Worley, Karen, PhD, Allen, J. Daniel, PharmD, Yang, Winnie, PharmD, Quon, Nicole C., PhD, Mullins, C. Daniel, PhD, Kahler, Kristijan H., PhD, RPh, Crown, William, PhD

“…Abstract Evidence-based health care decisions are best informed by comparisons of all relevant interventions used to treat conditions in specific patient…”
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Results of a retrospective, observational pilot study using electronic medical records to assess the prevalence and characteristics of patients with resistant hypertension in an ambulatory care setting by McAdam-Marx, Carrie, PhD, Ye, Xiangyang, MS, Sung, Jennifer C., PharmD, MS, Brixner, Diana I., PhD, Kahler, Kristijan H., PhD

“…Abstract Background: Resistant hypertension, or failure to attain blood pressure (BP) goals while treated with ≥3 antihypertensives (including a diuretic),…”
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Treatment Dynamics of Newly Marketed Drugs and Implications for Comparative Effectiveness Research by Gagne, Joshua J., PharmD, ScD, Bykov, Katsiaryna, PharmD, MS, Willke, Richard J., PhD, Kahler, Kristijan H., RPh, PhD, Subedi, Prasun, PhD, Schneeweiss, Sebastian, MD, ScD

“…Abstract Objectives Clinicians and payers require rapid comparative effectiveness (CE) evidence generation to inform decisions for new drugs. We empirically…”
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A Unified Framework for Classification of Methods for Benefit-Risk Assessment by Najafzadeh, Mehdi, PhD, Schneeweiss, Sebastian, MD, ScD, Choudhry, Niteesh, MD, PhD, Bykov, Katsiaryna, PharmD, MS, Kahler, Kristijan H., RPh, PhD, Martin, Diane P., PhD, Gagne, Joshua J., PharmD, ScD

“…Abstract Background Patients, physicians, and other decision makers make implicit but inevitable trade-offs among risks and benefits of treatments. Many…”
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Identification and mapping of worldwide sources of generic real‐world data by Wang, Xuan, Lahoz, Raquel, Jawla, Shantanu, Przybysz, Raymond, Kahler, Kristijan H., Burdukova, Lisa, Venkata, Shiva Kumar, Nassim, Maria, Jalapu, Anil, Justo, Nahila

“…Purpose The demand for real‐world data as supportive evidence to traditional clinical studies has increased in the past few years. The present study aimed to…”
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Impact of Oral Antihyperglycemic Therapy on All-Cause Mortality Among Patients With Diabetes in the Veterans Health Administration by Kahler, Kristijan H, Rajan, Mangala, Rhoads, George G, Safford, Monika M, Demissie, Kitaw, Lu, Shou-En, Pogach, Leonard M

“…OBJECTIVE:-- The objective of this analysis was to evaluate the impact of several classes of oral antihyperglycemic therapy relative to sulfonylurea…”
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Inhaled corticosteroid use in patients with chronic obstructive pulmonary disease and the risk of pneumonia: a retrospective claims data analysis by Yawn, Barbara P, Li, Yunfeng, Tian, Haijun, Zhang, Jie, Arcona, Steve, Kahler, Kristijan H

“…The use of inhaled corticosteroids in patients with chronic obstructive pulmonary disease (COPD) has been associated with an increased risk of pneumonia in…”
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Comparison of Benefit-Risk Assessment Methods for Prospective Monitoring of Newly Marketed Drugs: A Simulation Study by Gagne, Joshua J., PharmD, ScD, Najafzadeh, Mehdi, PhD, Choudhry, Niteesh K., MD, PhD, Bykov, Katsiaryna, PharmD, MS, Kahler, Kristijan H., PhD, Martin, Diane, PhD, Rogers, James R, Schneeweiss, Sebastian, MD, ScD

“…Abstract Objectives To compare benefit-risk assessment (BRA) methods for determining whether and when sufficient evidence exists to indicate that one drug is…”
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Patients with irritable bowel syndrome or constipation have an increased risk for ischaemic colitis by SUH, D.‐C., KAHLER, K. H., CHOI, I.‐S., SHIN, H., KRALSTEIN, J., SHETZLINE, M.

“…Summary Aims To estimate the relative risk for ischaemic colitis in patients with and without irritable bowel syndrome or constipation, and to evaluate the…”
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STaRT-RWE: structured template for planning and reporting on the implementation of real world evidence studies by Wang, Shirley V, Pinheiro, Simone, Hua, Wei, Arlett, Peter, Uyama, Yoshiaki, Berlin, Jesse A, Bartels, Dorothee B, Kahler, Kristijan H, Bessette, Lily G, Schneeweiss, Sebastian

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The Economic Cost of Diabetes in Canada, 1998 by DAWSON, Keith G, GOMES, Daniel, GERSTEIN, Hertzel, BLANCHARD, James F, KAHLER, Kristijan H

“…The Economic Cost of Diabetes in Canada, 1998 Keith G. Dawson , MD, PHD 1 , Daniel Gomes , MSC 2 , Hertzel Gerstein , MD, MSC 3 , James F. Blanchard , MD, PHD…”
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Prospective Benefit-Risk Monitoring of New Drugs for Rapid Assessment of Net Favorability in Electronic Health Care Data by Gagne, Joshua J., PharmD, ScD, Bykov, Katsiaryna, PharmD, MS, Najafzadeh, Mehdi, PhD, Choudhry, Niteesh K., MD, PhD, Martin, Diane P., PhD, Kahler, Kristijan H., PhD, Rogers, James R., BA, BS, Schneeweiss, Sebastian, MD, ScD

“…Abstract Background Benefit-risk assessment (BRA) methods can combine measures of benefits and risks into a single value. Objectives To examine BRA metrics for…”
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Consequences of poor compliance with bisphosphonates by Briesacher, Becky A, Andrade, Susan E, Yood, Robert A, Kahler, Kristijan H

“…Abstract Background Prior research on the ability of bisphosphonates to prevent fractures and related health care utilization has been based on high levels of…”
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Impairment in work productivity and health-related quality of life in patients with IBS by Dean, Bonnie B, Aguilar, Daniel, Barghout, Victoria, Kahler, Kristijan H, Frech, Feride, Groves, David, Ofman, Joshua J

“…Irritable bowel syndrome (IBS) is a long-term and episodic medical disorder shown to have an impact on work productivity and health-related quality of life…”
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Letter by Olson et al Regarding Article, “Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies: First Results From the RCT DUPLICATE Initiative” by Olson, Melvin (Skip), Deshpande, Chinmay, Kahler, Kristijan H.

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Systemic Medication Associations with Presumed Advanced or Uncontrolled Primary Open-Angle Glaucoma by Zheng, Wei, Dryja, Thaddeus P., Wei, Zhongyuan, Song, Dongying, Tian, Haijun, Kahler, Kristijan H., Khawaja, Anthony P.

“…To identify associations between systemic medications and primary open-angle glaucoma (POAG) requiring a procedure using United States insurance claims data in…”
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The effect of health related quality of life on reported use of health care resources in patients with osteoarthritis and rheumatoid arthritis: a longitudinal analysis by ETHGEN, Olivier, KAHLER, Kristijan H, KONG, Sheldon X, REGINSTER, Jean-Yves, WOLFE, Frederick

“…OBJECTIVE: In today's cost conscious environment, health services researchers are consistently trying to find ways to predict future health care resource…”
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Validation of the dermatology life quality index and the work productivity and activity impairment-chronic hand dermatitis questionnaire in chronic hand dermatitis by Reilly, Margaret C., Lavin, Philip T., Kahler, Kristijan H., Pariser, David M.

“…In a double-blind, randomized trial of 257 patients with chronic hand dermatitis, the validity, reproducibility, and responsiveness of the Dermatology Life…”
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Group-based trajectory modeling to assess adherence to biologics among patients with psoriasis by Li, Yunfeng, Zhou, Huanxue, Cai, Beilei, Kahler, Kristijan H, Tian, Haijun, Gabriel, Susan, Arcona, Steve

“…Proportion of days covered (PDC), a commonly used adherence metric, does not provide information about the longitudinal course of adherence to treatment over…”
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