Search Results - "Kagita, Sailaja"

Role of Antioxidant Gene Polymorphisms in Risk and Prognosis of Chronic Myeloid Leukemia by Kagita, Sailaja, Digumarti, Raghunadharao, Gundeti, Sadhashivudu

“…Introduction: We aimed to investigate the possible role of antioxidant enzyme polymorphisms CAT -21A/T (rs7943316), CAT -262C/T (rs1001179), GPX1 -198C/T…”
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Correlation of C/EBPα expression with response and resistance to imatinib in chronic myeloid leukaemia by Kagita, Sailaja, Uppalapati, Srihari, Gundeti, Sadasivudu, Digumarti, Raghunadharao

“…Altered differentiation is a common feature of haematopoietic malignancies with poor prognosis. CAAT/enhancer binding protein alpha (C/EBPα) is a key…”
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Incidence of internal tandem duplications and D835 mutations of FLT3 gene in chronic myeloid leukemia patients from Southern India by Annamaneni, Sandhya, Kagita, Sailaja, Gorre, Manjula, Digumarti, Raghunadha Rao, Satti, Vishnupriya, Battini, Mohan Reddy

“…To screen two important FLT3 mutations (internal tandem duplication (ITD) and D835 point mutations) in chronic myeloid leukemia (CML) patients from Southern…”
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Significance of ATM Gene Polymorphisms in Chronic Myeloid Leukemia - a Case Control Study from India by Gorre, Manjula, Mohandas, Prajitha Edathara, Kagita, Sailaja, Cingeetham, Anuradha, Vuree, Sugunakar, Jarjapu, Sarika, Nanchari, Santhoshirani, Meka, Phanni Bhushann, Annamaneni, Sandhya, Dunna, Nageswara Rao, Digumarti, Raghunadharao, Satti, Vishnupriya

“…Background: Development of chronic myeloid leukemia (CML) involves formation of double strand breaks (DSBs) which are initially sensed by the ataxia…”
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Role of the MDM2 Promoter Polymorphism (-309T>G) in Acute Myeloid Leukemia Development by Cingeetham, Anuradha, Vuree, Sugunakar, Jiwatani, Sangeeta, Kagita, Sailaja, Dunna, Nageswara Rao, Meka, Phanni Bhushann, Gorre, Manjula, Annamaneni, Sandhya, Digumarti, Raghunadharao, Sinha, Sudha, Satti, Vishnupriya

“…Background: The human homologue of the mouse double minute 2 (MDM2) gene is a negative regulator of Tp53. MDM2-309T>G a functional promoter polymorphism was…”
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Influence of Caspase-9 polymorphisms on the development of Chronic Myeloid Leukemia- A case-control study by Edathara, Prajitha Mohandas, Gorre, Manjula, Kagita, Sailaja, Cingeetham, Anuradha, Annamaneni, Sandhya, Digumarti, Raghunadharao, Satti, Vishnupriya

“…Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder, characterized by the overproduction of myeloid cells in all stages of maturation. It is…”
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Impact of polymorphisms of TP53 Arg72Pro, excision repair cross-complementing Protein 1 Asn118Asn (C118T) and deletion in Intron 2 of BIM in chronic myeloid leukemia patients on imatinib treatment by Kagita, Sailaja, Gundeti, Sadasivudu, Digumarti, Raghunadharao

“…Background: Imatinib (IM) results in durable responses in a large number of patients with chronic myeloid leukemia (CML). However, a substantial number…”
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A Rare Toxicity to Chemotherapy by Vallathol, Dilip Harindran, Alapati, Neeharika, Kagita, Sailaja, Digumarti, Raghunadharao

“…The use of chemotherapy is often limited by toxic side-effects caused to healthy cells. In general, most chemotherapy treatments cause DNA damage or stop cells…”
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Abstract 3858: Genetic polymorphisms of DNA repair genes in the origin and progression of chronic myeloid leukemia by Gorre, Manjula, Mohandas, Prajitha Edathara, Kagita, Sailaja, Cingeetham, Anuradha, Vuree, Sugunakar, Annamaneni, Sandhya, Digumarti, Raghunadharao, Satti, Vishnupriya

“…Abstract Background: The origin of Chronic Myeloid Leukaemia (CML) involves the formation of Double Strand Breaks (DSBs) which are initially sensed by the…”
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Incidence of Bcr-Abl kinase domain mutations in imatinib refractory chronic myeloid leukemia patients from South India by Kagita, Sailaja, Uppalapati, Srihari, Jiwatani, Sangeeta, Linga, Vijay Gandhi, Gundeti, Sadasivudu, Nagesh, Narayana, Digumarti, Raghunadharao

“…Mutations in the Bcr-Abl kinase domain (KD) are a major cause for acquired resistance to imatinib (IM) treatment and have been associated with progression and…”
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Assessment of BCR-ABL1 fusion transcripts and their association with response to imatinib treatment in chronic myeloid leukemia patients by Kagita, Sailaja, Mamidi, Tulasi, Digumarti, Leela, Gundeti, Sadasivudu, Digumarti, Raghunadharao

“…Objectives: BCR-ABL1 fusion transcripts with contrasting data on response to imatinib therapy have been reported from different parts of the world. Hence, the…”
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Methylation status of CEBPA gene promoter in chronic myeloid leukemia by Annamaneni, Sandhya, Kagita, Sailaja, Gorre, Manjula, Digumarti, Raghunadha Rao, Satti, Vishnupriya, Battini, Mohan Reddy

“…CCAAT/enhancer binding protein alpha is one of the crucial transcription factors for myeloid cell development that has been found to be involved in…”
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Association of XRCC5 VNTR polymorphism with the development of chronic myeloid leukemia by Gorre, Manjula, Mohandas, Prajitha Edathara, Kagita, Sailaja, Annamaneni, Sandhya, Digumarti, Raghunadharao, Satti, Vishnupriya

“…Double-strand breaks (DSBs) inducing agents influence the fidelity of DNA repair in both normal cells and leukemic cells, causing major genomic instability. In…”
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Association of promoter polymorphisms of Fas –FasL genes with development of Chronic Myeloid Leukemia by Edathara, Prajitha Mohandas, Gorre, Manjula, Kagita, Sailaja, Vuree, Sugunakar, Cingeetham, Anuradha, Nanchari, Santhoshi Rani, Meka, Phanni bhushann, Annamaneni, Sandhya, Digumarthi, Raghunadha Rao, Satti, Vishnupriya

“…Chronic myeloid leukemia (CML) is a monoclonal myeloproliferative disorder of hematopoietic stem cells (HSCs), characterized by reciprocal translocation,…”
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Association of XRCC1 gene polymorphisms with chronic myeloid leukemia in the population of Andhra Pradesh, India by Annamaneni, Sandhya, Gorre, Manjula, Kagita, Sailaja, Addepalli, Kasyap, Digumarti, Raghunadha Rao, Satti, Vishnupriya, Battini, Mohan Reddy

“…Chronic myeloid leukemia (CML), a clonal myeloproliferative disorder, is characterized primarily by the presence of chimeric BCR-ABL oncogene, and its…”
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Association of thymidylate synthase 5'-UTR 28bp tandem repeat and serine hydroxymethyltransfarase C1420T polymorphisms with susceptibility to acute leukemia by Dunna, Nageswara Rao, Naushad, Shaik Mohammad, Vuree, Sugunakar, Anuradha, Cingeetham, Sailaja, Kagita, Surekha, Damineni, Rao, Digumarti Raghunadha, Vishnupriya, Satti

“…The current study was aimed to elucidate the association of thymidylate synthase (TYMS) 5'- UTR 28bp tandem repeat and cytosolic serine…”
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Early molecular response in chronic myeloid leukemia patients predicts future response status by Kagita, Sailaja, Jiwtani, Sangeeta, Uppalapati, Srihari, Linga, Vijay Gandhi, Gundeti, Sadasivudu, Digumarti, Raghunadharao

“…Imatinib is the frontline therapy for chronic myeloid leukemia (CML) management. Most of the CML patients achieve major responses, but a proportion (nearly…”
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Significance of ATM Gene Polymorphisms in Chronic Myeloid Leukemia - a Case Control Study from India by Gorre, Manjula, Mohandas, Prajitha Edathara, Kagita, Sailaja, Cingeetham, Anuradha, Vuree, Sugunakar, Jarjapu, Sarika, Nanchari, Santhoshirani, Meka, Phanni Bhushann, Annamaneni, Sandhya, Dunna, Nageswara Rao, Digumarti, Raghunadharao, Satti, Vishnupriya

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Outcomes of Ewing’s sarcoma: Real-world scenario from the developing world—An 11-year analysis by Nasaka, Srividya, Ganta, Ranga Raman, Arigela, Ravi Sankar, Kalpathi, Krishnamani Iyer, Kota, Rajesh, Gullipalli, Muralidhar, Kagita, Sailaja, Pillai, Ashok Kumar, Kandula, Ramu, Bala, Joseph Stalin, Linga, Vijay Gandhi, Gundeti, Sadashivudu, Maddali, Lakshmi S., Digumarti, Raghunadharao

“…Abstract only…”
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Role of the MDM2 Promoter Polymorphism (-309T>G) in Acute Myeloid Leukemia Development by Cingeetham, Anuradha, Vuree, Sugunakar, Jiwatani, Sangeeta, Kagita, Sailaja, Dunna, Nageswara Rao, Meka, Phanni Bhushann, Gorre, Manjula, Annamaneni, Sandhya, Digumarti, Raghunadharao, Sinha, Sudha, Satti, Vishnupriya

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