Search Results - "Kagan, Amanda"

Phase 1 study of belinostat and adavosertib in patients with relapsed or refractory myeloid malignancies by Shafer, Danielle, Kagan, Amanda B., Rudek, Michelle A., Kmieciak, Maciej, Tombes, Mary Beth, Shrader, Ellen, Bandyopadhyay, Dipankar, Hudson, Daniel, Sankala, Heidi, Weir, Caryn, Lancet, Jeffrey E., Grant, Steven

“…Purpose Belinostat is an intravenous histone deacetylase inhibitor with approval for T-cell lymphomas. Adavosertib is a first in class oral Wee1 inhibitor…”
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DNA methyltransferase inhibitor exposure–response: Challenges and opportunities by Kagan, Amanda B., Garrison, Dominique A., Anders, Nicole M., Webster, Jonathan A., Baker, Sharyn D., Yegnasubramanian, Srinivasan, Rudek, Michelle A.

“…Although DNA methyltransferase inhibitors (DNMTis), such as azacitidine and decitabine, are used extensively in the treatment of myelodysplastic syndromes and…”
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A Novel 2-Carbon-Linked Dimeric Artemisinin With Potent Antileukemic Activity and Favorable Pharmacology by Kagan, Amanda B, Moses, Blake S, Mott, Bryan T, Rai, Ganesha, Anders, Nicole M, Rudek, Michelle A, Civin, Curt I

“…Acute myeloid leukemia (AML) remains a devastating disease, with low cure rates despite intensive standard chemotherapy regimens. In the past decade, targeted…”
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ART714 is a best-in-class antileukemic 2-carbon-linked dimeric artemisinin derivative by Kagan, Amanda B., Moses, Blake S., Lapidus, Rena, Mott, Bryan T., Rai, Ganesha, Anders, Nicole M., Hoag, Stephen W., Rudek, Michelle A., Civin, Curt I.

“…Purpose It has become increasingly clear that new multiagent combination regimens are required to improve survival rates in acute myeloid leukemia (AML). We…”
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Quantitation of navtemadlin in human plasma and brain tissue by liquid chromatography–tandem mass spectrometry by Kagan, Amanda B., Anders, Nicole M., Hemingway, Avelina, Lee, Eudocia Q., Kelly, Kevin R., Lee, Hans C., Xu‐Welliver, Meng, Piekarz, Richard, Rudek, Michelle A.

“…Navtemadlin is an orally bioavailable small molecule that blocks the protein–protein interaction between murine double minute 2 protein (MDM2) and the tumor…”
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A trainee-led quality improvement project to improve fertility preservation counseling and access to fertility preservation services for persons with cancer by Gupta, Arjun, Sena, Laura, Sedhom, Ramy, Scott, Susan Combs, Kagan, Amanda Brooks, Marple, Andrew Harris, Canzoniero, Jenna VanLiere, Hsu, Melinda Laine, Hussaini, Syed, Herati, Amin S., Reschke, Lauren, Antero, Maria F., Christianson, Mindy, Binder, Adam F, Chen, Allen Ray Sing, Donehower, Ross C., Marrone, Kristen

“…Abstract only 237 Background: For patients of reproductive age with cancer, counseling regarding reproductive risks associated with systemic therapy and…”
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FLT3 ITD AML Outcomes Are Impacted By Exposure to One Cycle of Cytarabine Based Consolidation, Pre- and Post-Transplant TKI Therapy, and Presence of Minimal Residual Disease (MRD) Prior to Allogeneic Blood or Marrow Transplant by Rebechi, Melanie, DeZern, Amy E., Kagan, Amanda, Smith, B. Douglas, Gojo, Ivana, Showel, Margaret M., Prince, Gabrielle T., Ghiaur, Gabriel, Gondek, Lukasz P., Matsui, William, Fuchs, Ephraim J., Luznik, Leo, McCurdy, Shannon R., Huff, Carol Ann, Swinnen, Lode J., Borrello, Ivan M., Gladstone, Douglas E., Bolanos-Meade, Javier, Ambinder, Richard F, Jones, Richard J., Levis, Mark J., Pratz, Keith

“…Background: FLT3 ITD AML is associated with high rates of relapse and short relapse free survival. Prognosis after relapse is extremely poor, making…”
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Trainee-Led Quality Improvement Project to Improve Fertility Preservation Counseling for Patients With Cancer by Sena, Laura A, Sedhom, Ramy, Scott, Susan, Kagan, Amanda, Marple, Andrew H, Canzoniero, Jenna V, Hsu, Melinda, Qasim Hussaini, Syed M, Herati, Amin S, Reschke, Lauren, Antero, Maria Facadio, Christianson, Mindy S, Binder, Adam F, Chen, Allen R, Donehower, Ross C, Marrone, Kristen A, Gupta, Arjun

“…Oncofertility counseling regarding the reproductive risks associated with cancer therapy is essential for quality cancer care. We aimed to increase the rate of…”
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