Search Results - "Kaffarnik, Magnus"

Early diagnosis of sepsis-related hepatic dysfunction and its prognostic impact on survival: a prospective study with the LiMAx test by Kaffarnik, Magnus F, Lock, Johan F, Vetter, Hannah, Ahmadi, Navid, Lojewski, Christian, Malinowski, Maciej, Neuhaus, Peter, Stockmann, Martin

“…Liver dysfunction can derive from severe sepsis and might be associated with poor prognosis. However, diagnosis of septic liver dysfunction is challenging due…”
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Correlation between plasma endothelin-1 levels and severity of septic liver failure quantified by maximal liver function capacity (LiMAx test). A prospective study by Kaffarnik, Magnus F, Ahmadi, Navid, Lock, Johan F, Wuensch, Tilo, Pratschke, Johann, Stockmann, Martin, Malinowski, Maciej

“…To investigate the relationship between the degree of liver dysfunction, quantified by maximal liver function capacity (LiMAx test) and endothelin-1, TNF-α and…”
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Liver Function, Quantified by LiMAx Test, After Major Abdominal Surgery. Comparison Between Open and Laparoscopic Approach by Kaffarnik, Magnus, Stoeger, Gabriel, Liebich, Julia, Grieser, Christian, Pratschke, Johann, Stockmann, Martin

“…Introduction Major abdominal surgery may lead to a systemic inflammatory response (SIRS) with a risk of organ failure. One possible trigger for a postoperative…”
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The obesity paradox in surgical intensive care patients with peritonitis by Utzolino, Stefan, MD, Ditzel, Christian M., MD, Baier, Peter K., MD, Hopt, Ulrich T., MD, Kaffarnik, Magnus F., MD

“…Abstract Purpose Although obesity is usually regarded as a risk factor in surgical patients, various observations have revealed a better outcome in the obese…”
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Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx) by Alraish, Rawan, Wicha, Sebastian G., Frey, Otto R., Roehr, Anka C., Pratschke, Johann, Stockmann, Martin, Wuensch, Tilo, Kaffarnik, Magnus

“…Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and…”
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Performance characterization of a novel electronic number connection test to detect minimal hepatic encephalopathy in cirrhotic patients by Wuensch, Tilo, Ruether, Darius Ferenc, Zöllner, Caroline, Mueller, Tobias, Jung, Tobias, Kaffarnik, Magnus, Kassner, Ursula, Schott, Eckart, Kiefer, Stephan, Pratschke, Johann, Stockmann, Martin, Jara, Maximilian

“…BACKGROUND AND AIMHepatic encephalopathy (HE) is a frequent complication of cirrhosis, characterized by cognitive deficits that negatively impact patients’…”
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Tigecycline Dosing Strategies in Critically Ill Liver-Impaired Patients by Amann, Lisa F, Alraish, Rawan, Broeker, Astrid, Kaffarnik, Magnus, Wicha, Sebastian G

“…This study investigated tigecycline exposure in critically ill patients from a population pharmacokinetic perspective to support rational dosing in intensive…”
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Unplanned discharges from a surgical intensive care unit: Readmissions and mortality by Utzolino, Stefan, MD, Kaffarnik, Magnus, MD, Keck, Tobias, MD, Berlet, Meike, MD, Hopt, Ulrich Theodor, MD

“…Abstract Purpose There is great patient turnover every day on surgical intensive care units (SICUs). Surgical intensive care unit beds are provided for major…”
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Hepatic CYP1A2 activity in liver tumors and the implications for preoperative volume-function analysis by Wuensch, Tilo, Heucke, Niklas, Wizenty, Jonas, Quint, Janina, Sinn, Bruno, Arsenic, Ruza, Jara, Maximilian, Kaffarnik, Magnus, Pratschke, Johann, Stockmann, Martin

“…Dynamic liver function assessment by the [ C]methacetin maximal liver function capacity (LiMAx) test reflects the overall hepatic cytochrome -450 (CYP) 1A2…”
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Dynamic liver function is an independent predictor of recurrence-free survival after curative liver resection for HCC - A retrospective cohort study by Blüthner, Elisabeth, Bednarsch, Jan, Malinowski, Maciej, Binder, Phung, Pratschke, Johann, Stockmann, Martin, Kaffarnik, Magnus

“…Hepatocellular carcinoma is the fifth most prevalent cancer worldwide. High tumour recurrence is the most common cause of the impaired 5-year survival rate of…”
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Non‐invasive structure–function assessment of the liver by 2D time‐harmonic elastography and the dynamic Liver MAximum capacity (LiMAx) test by Heucke, Niklas, Wuensch, Tilo, Mohr, Julia, Kaffarnik, Magnus, Arsenic, Ruza, Sinn, Bruno, Müller, Tobias, Pratschke, Johann, Stockmann, Martin, Sack, Ingolf, Tzschätzsch, Heiko

“…Background and Aim Accurate assessment of structural and functional characteristics of the liver could improve the diagnosis and the clinical management of…”
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Linezolid in liver failure: exploring the value of the maximal liver function capacity (LiMAx) test in a pharmacokinetic pilot study by Wicha, Sebastian G., Frey, Otto R., Roehr, Anka C., Pratschke, Johann, Stockmann, Martin, Alraish, Rawan, Wuensch, Tilo, Kaffarnik, Magnus

“…•Linezolid trough levels (Cmin) were measured in 28 patients with varying liver function.•64% of samples were above the recommended Cmin of 8…”
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Clostridium difficile Infection: Epidemiology, Clinical Presentation, Therapy and Prevention by Kaffarnik, Magnus, Isner, Caroline, Hamsen, Uwe

“…Clostridium difficile infections (CDI) are common causes of diarrhoea in hospitalised medical and surgical patients. Clinical presentation ranges from mild…”
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Correlation between plasma endothelin-1 levels and severity of septic liver failure quantified by maximal liver function capacity by Kaffarnik, Magnus F, Ahmadi, Navid, Lock, Johan F, Wuensch, Tilo, Pratschke, Johann, Stockmann, Martin, Malinowski, Maciej

“…Aim To investigate the relationship between the degree of liver dysfunction, quantified by maximal liver function capacity (LiMAx test) and endothelin-1,…”
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Liver function, quantified by the LiMAx test, as a predictor for the clinical outcome of critically ill patients treated with linezolid by Alraish, Rawan, Wicha, Sebastian G, Frey, Otto R, Roehr, Anka C, Pratschke, Johann, Stockmann, Martin, Wuensch, Tilo, Kaffarnik, Magnus

“…Critically ill patients commonly suffer from infections that require antimicrobial therapy. In previous studies, liver dysfunction was shown to have an…”
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The use of bedside electromagnetically guided nasointestinal tube for jejunal feeding of critical ill surgical patients by Kaffarnik, Magnus Friedrich, Lock, Johan Friso, Wassilew, Georgi, Neuhaus, Peter

“…Gastral nutrition in critically ill surgical patients can be difficult because of gastric paresis and a large number of patients fail to reach required caloric…”
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Impact of enterococcus on immunocompetent and immunosuppressed patients with perforation of the small or large bowel by Kaffarnik, Magnus Friedrich, Urban, Max, Hopt, Ulrich Theodor, Utzolino, Stefan

“…The role of enterococcus in intraabdominal infection remains controversial. A retrospective study of 473 patients with bowel perforation was conducted to…”
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Catecholamine Dosing and Survival in Adult Intensive Care Unit Patients by Kastrup, Marc, Braun, Jan, Kaffarnik, Magnus, von Dossow-Hanfstingl, Vera, Ahlborn, Robert, Wernecke, Klaus-D, Spies, Claudia

“…Background Volume management and vasopressor support remain the gold standard of critical care for patients with shock. However, prolonged therapy with…”
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Identification of serological markers for pre- and postoperative fasting periods by Wuensch, Tilo, Quint, Janina, Mueller, Verena, Mueller, Anne, Wizenty, Jonas, Kaffarnik, Magnus, Kern, Barbara, Stockmann, Martin, Biebl, Matthias, Pratschke, Johann, Aigner, Felix

“…Summary Background & aims Prolonged preoperative fasting periods lead to catabolic states and decelerate recovery after surgery. Valid plasma markers…”
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