Search Results - "Kafatos, Fotis"

Anopheles gambiae PGRPLC-mediated defense against bacteria modulates infections with malaria parasites by Meister, Stephan, Agianian, Bogos, Turlure, Fanny, Relógio, Angela, Morlais, Isabelle, Kafatos, Fotis C, Christophides, George K

“…Recognition of peptidoglycan (PGN) is paramount for insect antibacterial defenses. In the fruit fly Drosophila melanogaster, the transmembrane PGN Recognition…”
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Leucine-Rich Repeat Protein Complex Activates Mosquito Complement in Defense Against Plasmodium Parasites by Povelones, Michael, Waterhouse, Robert M, Kafatos, Fotis C, Christophides, George K

“…Leucine-rich repeat-containing proteins are central to host defense in plants and animals. We show that in the mosquito Anopheles gambiae, two such proteins…”
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Evolutionary Dynamics of Immune-Related Genes and Pathways in Disease-Vector Mosquitoes by Waterhouse, Robert M, Kriventseva, Evgenia V, Meister, Stephan, Xi, Zhiyong, Alvarez, Kanwal S, Bartholomay, Lyric C, Barillas-Mury, Carolina, Bian, Guowu, Blandin, Stephanie, Christensen, Bruce M, Dong, Yuemei, Jiang, Haobo, Kanost, Michael R, Koutsos, Anastasios C, Levashina, Elena A, Li, Jianyong, Ligoxygakis, Petros, MacCallum, Robert M, Mayhew, George F, Mendes, Antonio, Michel, Kristin, Osta, Mike A, Paskewitz, Susan, Shin, Sang Woon, Vlachou, Dina, Wang, Lihui, Wei, Weiqi, Zheng, Liangbiao, Zou, Zhen, Severson, David W, Raikhel, Alexander S, Kafatos, Fotis C, Dimopoulos, George, Zdobnov, Evgeny M, Christophides, George K

“…Mosquitoes are vectors of parasitic and viral diseases of immense importance for public health. The acquisition of the genome sequence of the yellow fever and…”
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Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae by Lombardo, Fabrizio, Ghani, Yasmeen, Kafatos, Fotis C, Christophides, George K

“…Reverse genetics in the mosquito Anopheles gambiae by RNAi mediated gene silencing has led in recent years to an advanced understanding of the mosquito immune…”
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Infection Intensity-Dependent Responses of Anopheles gambiae to the African Malaria Parasite Plasmodium falciparum by MENDES, Antonio M, AWONO-AMBENE, Parfait H, NSANGO, Sandrine E, COHUET, Anna, FONTENILLE, Didier, KAFATOS, Fotis C, CHRISTOPHIDES, George K, MORLAIS, Isabelle, VLACHOU, Dina

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Functional Genomic Analysis of Midgut Epithelial Responses in Anopheles during Plasmodium Invasion by Vlachou, Dina, Schlegelmilch, Timm, Christophides, George K., Kafatos, Fotis C.

“…Background: The malaria parasite Plasmodium must complete a complex developmental life cycle within Anopheles mosquitoes before it can be transmitted into the…”
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Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa by Mendes, Antonio M, Schlegelmilch, Timm, Cohuet, Anna, Awono-Ambene, Parfait, De Iorio, Maria, Fontenille, Didier, Morlais, Isabelle, Christophides, George K, Kafatos, Fotis C, Vlachou, Dina

“…In much of sub-Saharan Africa, the mosquito Anopheles gambiae is the main vector of the major human malaria parasite, Plasmodium falciparum. Convenient…”
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Effects of Mosquito Genes on Plasmodium Development by Osta, Mike A., Christophides, George K., Kafatos, Fotis C.

“…Malaria parasites must complete a complex developmental cycle in an Anopheles mosquito vector before transmission to a vertebrate host. Sexual development of…”
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Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae by Christophides, George K., Vlachou, Dina, Kafatos, Fotis C.

“…In much of Africa, the mosquito Anopheles gambiae is the major vector of human malaria, a devastating infectious disease caused by Plasmodium parasites. Vector…”
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Discovery of Plasmodium modulators by genome-wide analysis of circulating hemocytes in Anopheles gambiae by Pinto, Sofia B, Lombardo, Fabrizio, Koutsos, Anastasios C, Waterhouse, Robert M, McKay, Krista, An, Chunju, Ramakrishnan, Chandra, Kafatos, Fotis C, Michel, Kristin

“…Insect hemocytes mediate important cellular immune responses including phagocytosis and encapsulation and also secrete immune factors such as opsonins,…”
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Two C-type Lectins Cooperate to Defend Anopheles gambiae against Gram-negative Bacteria by Schnitger, Anna K.D., Yassine, Hassan, Kafatos, Fotis C., Osta, Mike A.

“…C-type lectins (CTLs) are a family of proteins that share a common structural motif, the carbohydrate recognition domain, and may act as receptors in pathogen…”
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In Vivo Identification of Novel Regulators and Conserved Pathways of Phagocytosis in A. gambiae by Moita, Luís F., Wang-Sattler, Rui, Michel, Kristin, Zimmermann, Timo, Blandin, Stephanie, Levashina, Elena A., Kafatos, Fotis C.

“…Anopheles gambiae uses effective immune responses, including phagocytosis, to fight microbial infection. We have developed a semiquantitative phagocytosis test…”
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Complement-Like Protein TEP1 Is a Determinant of Vectorial Capacity in the Malaria Vector Anopheles gambiae by Blandin, Stephanie, Shiao, Shin-Hong, Moita, Luis F, Janse, Chris J, Waters, Andrew P, Kafatos, Fotis C, Levashina, Elena A

“…Anopheles mosquitoes are major vectors of human malaria in Africa. Large variation exists in the ability of mosquitoes to serve as vectors and to transmit…”
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A genetic module regulates the melanization response of Anopheles to Plasmodium by Volz, Jennifer, Müller, Hans‐Michael, Zdanowicz, Agnieszka, Kafatos, Fotis C., Osta, Mike A.

“…Summary Two modes of refractoriness to Plasmodium, ookinete lysis and melanization, are known in the malaria vector, Anopheles gambiae. Melanization, a potent…”
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Anopheles and Plasmodium: from laboratory models to natural systems in the field by Cohuet, Anna, Osta, Mike A, Morlais, Isabelle, Awono-Ambene, Parfait H, Michel, Kristin, Simard, Frederic, Christophides, George K, Fontenille, Didier, Kafatos, Fotis C

“…Parasites that cause malaria must complete a complex life cycle in Anopheles vector mosquitoes in order to be transmitted from human to human. Previous…”
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SNP discovery and molecular evolution in Anopheles gambiae, with special emphasis on innate immune system by Cohuet, Anna, Krishnakumar, Sujatha, Simard, Frédéric, Morlais, Isabelle, Koutsos, Anastasios, Fontenille, Didier, Mindrinos, Michael, Kafatos, Fotis C

“…Anopheles innate immunity affects Plasmodium development and is a potential target of innovative malaria control strategies. The extent and distribution of…”
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Phylogenetic Perspectives in Innate Immunity by Hoffmann, Jules A., Kafatos, Fotis C., Janeway, Charles A., Ezekowitz, R. A. B.

“…The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent…”
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Comprehensive Survey of the Plasmodium Life Cycle by Genomic, Transcriptomic, and Proteomic Analyses by Hall, Neil, Karras, Marianna, Raine, J. Dale, Carlton, Jane M, Kooij, Taco W. A, Berriman, Matthew, Florens, Laurence, Janssen, Christoph S, Pain, Arnab, Christophides, Georges K, James, Keith, Rutherford, Kim, Harris, Barbara, Harris, David, Churcher, Carol, Quail, Michael A, Ormond, Doug, Doggett, Jon, Trueman, Holly E, Mendoza, Jacqui, Bidwell, Shelby L, Rajandream, Marie-Adele, Carucci, Daniel J, Yates, John R, Kafatos, Fotis C, Janse, Chris J, Barrell, Bart, Turner, C. Michael R, Waters, Andrew P, Sinden, Robert E

“…Plasmodium berghei and Plasmodium chabaudi are widely used model malaria species. Comparison of their genomes, integrated with proteomic and microarray data,…”
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VectorBase: a data resource for invertebrate vector genomics by Lawson, Daniel, Arensburger, Peter, Atkinson, Peter, Besansky, Nora J, Bruggner, Robert V, Butler, Ryan, Campbell, Kathryn S, Christophides, George K, Christley, Scott, Dialynas, Emmanuel, Hammond, Martin, Hill, Catherine A, Konopinski, Nathan, Lobo, Neil F, MacCallum, Robert M, Madey, Greg, Megy, Karine, Meyer, Jason, Redmond, Seth, Severson, David W, Stinson, Eric O, Topalis, Pantelis, Birney, Ewan, Gelbart, William M, Kafatos, Fotis C, Louis, Christos, Collins, Frank H

“…VectorBase (http://www.vectorbase.org) is an NIAID-funded Bioinformatic Resource Center focused on invertebrate vectors of human pathogens. VectorBase…”
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Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae by Meister, S, Kanzok, S.M, Zheng, X.I, Luna, C, Li, T.R, Hoa, N.T, Clayton, J.R, White, K.P, Kafatos, F.C, Christophides, G.K

“…We show that, in the malaria vector Anopheles gambiae, expression of Cecropin 1 is regulated by REL2, an NF-kappaB-like transcription factor orthologous to…”
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