Search Results - "Kaethner, Marc"
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Transforming growth factor-β signalling regulates protoscolex formation in the Echinococcus multilocularis metacestode
Published in Frontiers in cellular and infection microbiology (22-03-2023)“…The lethal zoonosis alveolar echinococcosis (AE) is caused by tumor-like, infiltrative growth of the metacestode larval stage of the tapeworm . We previously…”
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Targeted and non-targeted proteomics to characterize the parasite proteins of Echinococcus multilocularis metacestodes
Published in Frontiers in cellular and infection microbiology (30-05-2023)“…The larval stage of the cestode is the causative agent of alveolar echinococcosis. To investigate the biology of these stages and to test novel compounds,…”
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3
In vitro activities of Dithiocarbamate Derivatives against Echinococcus multilocularis metacestode vesicles
Published in Tropical medicine and infectious disease (12-12-2023)“…The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the severe zoonotic disease alveolar echinococcosis. New treatment options are…”
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Dual inhibition of the Echinococcus multilocularis energy metabolism
Published in Frontiers in veterinary science (05-08-2022)“…Alveolar echinococcosis is caused by the metacestode stage of the zoonotic parasite Echinococcus multilocularis . Current chemotherapeutic treatment options…”
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Maca against Echinococcosis?—A Reverse Approach from Patient to In Vitro Testing
Published in Pathogens (Basel) (01-10-2021)“…Drug-based treatment of alveolar echinococcosis (AE) with benzimidazoles is in most cases non-curative, thus has to be taken lifelong. Here, we report on a…”
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The sibling sRNAs NgncR_162 and NgncR_163 of Neisseria gonorrhoeae participate in the expression control of metabolic, transport and regulatory proteins
Published in Microbiology (Society for General Microbiology) (01-11-2017)“…Neisseria gonorrhoeae is the causative agent of gonorrhoea, the second most common bacterial sexually transmitted disease. Riboregulation mediated by small…”
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Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus sensu stricto
Published in PLoS neglected tropical diseases (04-08-2023)“…Echinococcus multilocularis and E. granulosus s.l. are the causative agents of alveolar and cystic echinococcosis, respectively. Drug treatment options for…”
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The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM PZQ Orthologs
Published in ACS medicinal chemistry letters (09-11-2023)“…The anthelmintic drug praziquantel remains a key clinical therapy for treating various diseases caused by parasitic flatworms. The parasite target of…”
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The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPMPZQ Orthologs
Published in ACS medicinal chemistry letters (09-11-2023)“…The anthelmintic drug praziquantel remains a key clinical therapy for treating various diseases caused by parasitic flatworms. The parasite target of…”
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Journal Article -
10
In Vitro Activities of Dithiocarbamate Derivatives against IEchinococcus multilocularis/I Metacestode Vesicles
Published in Tropical medicine and infectious disease (01-12-2023)“…The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the severe zoonotic disease alveolar echinococcosis. New treatment options are…”
Get full text
Journal Article