Search Results - "Kadlec, Andrew"

The Human Microcirculation: Regulation of Flow and Beyond by Gutterman, David D, Chabowski, Dawid S, Kadlec, Andrew O, Durand, Matthew J, Freed, Julie K, Ait-Aissa, Karima, Beyer, Andreas M

“…The microcirculation is responsible for orchestrating adjustments in vascular tone to match local tissue perfusion with oxygen demand. Beyond this metabolic…”
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Role of PGC-1α in Vascular Regulation: Implications for Atherosclerosis by Kadlec, Andrew O, Chabowski, Dawid S, Ait-Aissa, Karima, Gutterman, David D

“…Mitochondrial dysfunction results in high levels of oxidative stress and mitochondrial damage, leading to disruption of endothelial homeostasis. Recent…”
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Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction by Ait-Aissa, Karima, Kadlec, Andrew O, Hockenberry, Joseph, Gutterman, David D, Beyer, Andreas M

“…A rise in reactive oxygen species (ROS) may contribute to cardiovascular disease by reducing nitric oxide (NO) levels, leading to loss of NO's vasodilator and…”
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Physiological Consequences of Coronary Arteriolar Dysfunction and Its Influence on Cardiovascular Disease by Allaqaband, Hassan, Gutterman, David D, Kadlec, Andrew O

“…To date, the major focus of diagnostic modalities and interventions to treat coronary artery disease has been the large epicardial vessels. Despite substantial…”
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The Yin and Yang of endothelium-derived vasodilator factors by Kadlec, Andrew O, Gutterman, David D

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PGC-1α (Peroxisome Proliferator–Activated Receptor γ Coactivator 1-α) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal Pressure by Kadlec, Andrew O, Chabowski, Dawid S, Ait-Aissa, Karima, Hockenberry, Joseph C, Otterson, Mary F, Durand, Matthew J, Freed, Julie K, Beyer, Andreas M, Gutterman, David D

“…Blood flow through healthy human vessels releases NO to produce vasodilation, whereas in patients with coronary artery disease (CAD), the mediator of dilation…”
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Mitochondrial signaling in the vascular endothelium: beyond reactive oxygen species by Kadlec, Andrew O., Beyer, Andreas M., Ait-Aissa, Karima, Gutterman, David D.

“…Traditionally, the mitochondria have been viewed as the cell’s powerhouse, producing energy in the form of ATP. As a byproduct of ATP formation, the…”
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Microvascular Adaptations to Exercise: Protective Effect of PGC-1 Alpha by Kadlec, Andrew O, Barnes, Chad, Durand, Matthew J, Gutterman, David D

“…Abstract BACKGROUND Sedentary behavior and obesity are major risk factors for cardiovascular disease. Regular physical activity has independent protective…”
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Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease by Ait-Aissa, Karima, Ebben, Johnathan D., Kadlec, Andrew O., Beyer, Andreas M.

“…[Display omitted] Aging, cancer, and chronic disease have remained at the forefront of basic biological research for decades. Within this context, significant…”
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Hypertension during Weight Lifting Reduces Flow-Mediated Dilation in Nonathletes by BUCHANAN, CULLEN E, KADLEC, ANDREW O, HOCH, ANNE Z, GUTTERMAN, DAVID D, DURAND, MATTHEW J

“…PURPOSEThe purpose of this study was to determine whether increased intraluminal pressure is the damaging factor that reduces flow-mediated dilation (FMD) in…”
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Lysophosphatidic acid acts on LPA1 receptor to increase H2O2 during flow‐induced dilation in human adipose arterioles by Chabowski, Dawid S, Kadlec, Andrew O, Ait‐Aissa, Karima, Hockenberry, Joseph C, Pearson, Paul J, Beyer, Andreas M, Gutterman, David D

“…Background and Purpose NO produces arteriolar flow‐induced dilation (FID) in healthy subjects but is replaced by mitochondria‐derived hydrogen peroxide…”
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Effect of Renal Function on Prognosis in Chronic Heart Failure by Löffler, Adrián Ignacio, MD, Cappola, Thomas P., MD, ScM, Fang, James, MD, Hetzel, Scott J., MS, Kadlec, Andrew, BA, Astor, Brad, PhD, MPH, Sweitzer, Nancy K., MD, PhD

“…Renal dysfunction (RD) is associated with increased mortality in heart failure (HF). The aim of this study was to identify whether worsened or improved renal…”
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YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α by Mammoto, Akiko, Muyleart, Megan, Kadlec, Andrew, Gutterman, David, Mammoto, Tadanori

“…Mitochondria contribute to key processes of cellular function, while mitochondrial dysfunction is implicated in metabolic disorders, neurodegenerative…”
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High-resolution, real-time, and nonfluoroscopic 3-dimensional cardiac imaging and catheter navigation in humans using a novel dielectric-based system by Romanov, Alexander, Dichterman, Eli, Schwartz, Yitzhack, Ibragimov, Zalman, Ben-David, Yehonatan, Rodriguez, Haim, Pokushalov, Evgeny, Siddiqui, Usman R., Kadlec, Andrew, Ben-Haim, Shlomo A.

“…Catheter navigation and 3-dimensional (3D) cardiac mapping are essential components of minimally invasive electrophysiological procedures. The purpose of this…”
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Adapt or Perish by Chabowski Dawid, Kadlec, Andrew, Dellostritto, Daniel, Gutterman, David

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Adapt or Perish: Updating the Predoctoral Training Model by Chabowski, Dawid, Kadlec, Andrew, Dellostritto, Daniel, Gutterman, David

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Adapt or Perish – Updating the Pre-doctoral Training Model by Chabowski, Dawid, Kadlec, Andrew, Dellostritto, Daniel, Gutterman, David

“…The fate of biomedical research lies in the hands of future generations of scientists. In recent decades the diversity of scientific career opportunities has…”
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LPA‐induced activation of LPA1 receptor leads to the loss of NO‐mediated flow‐induced dilation in human microvessels by Chabowski, Dawid S., Ait‐Aissa, Karima, Kadlec, Andrew O., Hockenberry, Joseph H., Beyer, Andreas M., Gutterman, David D.

“…Introduction Flow‐induced dilation (FID) in arterioles from patients with coronary artery disease (CAD) is dependent on hydrogen peroxide (H2O2) rather than…”
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LPA‐induced activation of LPA 1 receptor leads to the loss of NO‐mediated flow‐induced dilation in human microvessels by Chabowski, Dawid S., Ait‐Aissa, Karima, Kadlec, Andrew O., Hockenberry, Joseph H., Beyer, Andreas M., Gutterman, David D.

“…Abstract only…”
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Lysophosphatidic acid acts on LPA 1 receptor to increase H 2 O 2 during flow-induced dilation in human adipose arterioles by Chabowski, Dawid S, Kadlec, Andrew O, Ait-Aissa, Karima, Hockenberry, Joseph C, Pearson, Paul J, Beyer, Andreas M, Gutterman, David D

“…NO produces arteriolar flow-induced dilation (FID) in healthy subjects but is replaced by mitochondria-derived hydrogen peroxide (mtH O ) in patients with…”
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