Search Results - "Kadieva, Madina G"

Synthesis and Structure–Activity Relationship (SAR) of (5,7-Disubstituted 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidin-2-yl)-methylamines as Potent Serotonin 5-HT6 Receptor (5-HT6R) Antagonists by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Kysil, Volodymyr M, Mitkin, Oleg D, Tkachenko, Sergey E, Okun, Ilya M

“…Syntheses, biological evaluation as 5-HT6 receptor (5-HT6R) antagonists, and structure–activity relationships for a series of novel 5,7-disubstituted…”
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(3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: Potent and Selective Antagonists of the Serotonin 5-HT6 Receptor by Ivachtchenko, Alexandre V, Dmitriev, Dmitri E, Golovina, Elena S, Kadieva, Madina G, Koryakova, Angela G, Kysil, Volodymyr M, Mitkin, Oleg D, Okun, Ilya M, Tkachenko, Sergey E, Vorobiev, Anton A

“…5-HT6 receptors are exclusively localized in the CNS and have high affinity with many psychotropic agents. Though the role of this receptor in many CNS…”
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Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT6 receptor antagonists by Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Kysil, Volodymyr M., Mitkin, Oleg D., Tkachenko, Sergey E., Okun, Ilya

“…Syntheses of a series of novel 3-sulfonyl-pyrazolo[1,5-a]pyrimidines and their 5-HT6 receptor antagonistic structure–activity relationship are disclosed. The…”
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Antagonists of 5-HT6 receptors. Substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines and 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[4,3-d]pyrimidines—Synthesis and ‘structure–activity’ relationship by Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Kysil, Volodymyr M., Mitkin, Oleg D., Vorobiev, Anton A., Okun, Ilya

“…Synthesis and biological evaluation of a new series of structurally unrestricted and intramolecular hydrogen bond restricted derivatives of…”
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2-Substituted 5,6-dimethyl-3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines: new series of highly potent and specific serotonin 5-HT6 receptor antagonists by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Koryakova, Angela G, Mitkin, Oleg D, Tkachenko, Sergey E, Kysil, Volodymyr M, Okun, Ilya

“…Syntheses, biological evaluation, and structure-activity relationships for a series of novel 2-substituted…”
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Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT6 receptor antagonists by IVACHTCHENKO, Alexandre V, DMITRIEV, Dmitri E, VOROBIOV, Anton A, GOLOVINA, Elena S, DUBROVSKAYA, Elena S, KADIEVA, Madina G, KORYAKOVA, Angela G, KYSIL, Volodymyr M, MITKIN, Oleg D, TKACHENKO, Sergey E, OKUN, Ilya M

“…Synthesis and biological evaluation of 1 ('angular') and 2 ('linear') cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines as novel ligands of the…”
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Synthesis and biological study of 3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines as potent and selective serotonin 5-HT6 receptor antagonists by Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Koryakova, Angela G., Kovalenko, Sergiy M., Mitkin, Oleg D., Okun, Ilya M., Ravnyeyko, Irina M., Tkachenko, Sergey E., Zaremba, Oleg V.

“…A number of 3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines were prepared and their 5-HT6 receptor binding affinity and ability to inhibit the…”
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Synthesis and Structure–Activity Relationship (SAR) of (5,7-Disubstituted 3-phenylsulfonyl-pyrazolo[1,5- a ]pyrimidin-2-yl)-methylamines as Potent Serotonin 5-HT 6 Receptor (5-HT 6 R) Antagonists by Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Kysil, Volodymyr M., Mitkin, Oleg D., Tkachenko, Sergey E., Okun, Ilya M.

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Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: Selective Serotonin 5-HT6 Receptor Antagonists by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Koryakova, Angela G, Kovalenko, Sergiy M, Mitkin, Oleg D, Okun, Ilya M, Ravnyeyko, Irina M, Tkachenko, Sergey E, Zaremba, Oleg V

“…Here we present the solution phase parallel synthesis of a combinatorial library consisting of 776 new substituted…”
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Antagonists of 5-HT6 receptors. Substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines and 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[4,3-d]pyrimidinesaSynthes is and astructureaactivitya relationship by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Kysil, Volodymyr M, Mitkin, Oleg D, Vorobiev, Anton A, Okun, Ilya

“…Synthesis and biological evaluation of a new series of structurally unrestricted and intramolecular hydrogen bond restricted derivatives of…”
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2-Substituted 5,6-dimethyl-3-phenylsulfonyl-pyrazolo[1,5- a]pyrimidines: New series of highly potent and specific serotonin 5-HT 6 receptor antagonists by Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Koryakova, Angela G., Mitkin, Oleg D., Tkachenko, Sergey E., Kysil, Volodymyr M., Okun, Ilya

“…Syntheses, biological evaluation, and structure–activity relationships for a series of novel 2-substituted 3-benzenesulfonyl-5,6-dimethyl-pyrazolo[1,5-…”
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(3-Phenylsulfonylcycloalkano[ e and d ]pyrazolo[1,5- a ]pyrimidin-2-yl)amines: Potent and Selective Antagonists of the Serotonin 5-HT 6 Receptor by Ivachtchenko, Alexandre V., Dmitriev, Dmitri E., Golovina, Elena S., Kadieva, Madina G., Koryakova, Angela G., Kysil, Volodymyr M., Mitkin, Oleg D., Okun, Ilya M., Tkachenko, Sergey E., Vorobiev, Anton A.

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Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT sub(6) receptor antagonists by Ivachtchenko, Alexandre V, Dmitriev, Dmitri E, Golovina, Elena S, Dubrovskaya, Elena S, Kadieva, Madina G, Koryakova, Angela G, Kysil, Volodymyr M, Mitkin, Oleg D, Tkachenko, Sergey E, Okun, Ilya M, Vorobiov, Anton A

“…Synthesis and biological evaluation of 1 ('angular') and 2 ('linear') cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines as novel ligands of the…”
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Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5- a]pyrimidines and their evaluation as 5-HT 6 receptor antagonists by Ivachtchenko, Alexandre V., Dmitriev, Dmitri E., Golovina, Elena S., Dubrovskaya, Elena S., Kadieva, Madina G., Koryakova, Angela G., Kysil, Volodymyr M., Mitkin, Oleg D., Tkachenko, Sergey E., Okun, Ilya M., Vorobiov, Anton A.

“…We synthesized and investigated the cycloalkane-annelated 3-phenyl-pyrazolo[1,5- a]pyrimidine systems, 1 and 2, as a novel scaffold for the development of…”
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Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT sub(6 receptor antagonists) by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Kysil, Volodymyr M, Mitkin, Oleg D, Tkachenko, Sergey E, Okun, Ilya, Xaxzrpbfudlbqy-Uhfffaoysa-N, InChiKey: XGRULCORSXSJMU-UHFFFAOYSA-N, FHTHODOLGSGNKC-UHFFFAOYSA-N, WTCSFQDXLLFGFG-UHFFFAOYSA-N, CIJYPUVXZVJNIK-UHFFFAOYSA-N, CMMVQEMVPHMYAX-UHFFFAOYSA-N, KPHVCQHKHZETCF-UHFFFAOYSA-N, CJNJTBVSPDHDIH-UHFFFAOYSA-N, ZKKWRCSTEPFZDF-UHFFFAOYSA-N, NBASEYFJBAVLDK-UHFFFAOYSA-N, QOPOFWNBOBVJPE-UHFFFAOYSA-N, YAXQJPOZKDXPBY-UHFFFAOYSA-N, CWEKNSLCAWLROJ-UHFFFAOYSA-N, WNRRPUVNHOWZFD-UHFFFAOYSA-N, KDUSPNDDQIZEGT-UHFFFAOYSA-N, QSPVQFNITBFSRY-UHFFFAOYSA-N, CWHCBHFBRORBJX-UHFFFAOYSA-N, MDSIFERMIAZRAO-UHFFFAOYSA-N, XEKXWUDGXMEULY-UHFFFAOYSA-N, IAPLOUHCOKXYDI-UHFFFAOYSA-N, KVSJSNMBDMWWIA-UHFFFAOYSA-N, BQLYGLDNQZMPQV-UHFFFAOYSA-N, IUXYJICWWRCNRN-UHFFFAOYSA-N, DGZRDRVJWDVPCG-UHFFFAOYSA-N, LLRSKWJLJFTWMG-UHFFFAOYSA-N, MZLLXENSSNWXKW-UHFFFAOYSA-N, LYPYSDSVJRKEDT-UHFFFAOYSA-N, PVCZORLSESOJBZ-UHFFFAOYSA-N, BFOXZWKSDUOKPO-UHFFFAOYSA-N, DXULVPMDABIRHL-UHFFFAOYSA-N, WAWIENOYLSZDBE-UHFFFAOYSA-N, AKYBXIOZAWNEGP-UHFFFAOYSA-N, QKGIEOVAASUNSI-UHFFFAOYSA-N, YXXJGHIVBQTMRG-UHFFFAOYSA-N, WOZJSOBIIURLMO

“…Syntheses of a series of novel 3-sulfonyl-pyrazolo[1,5-a]pyrimidines and their 5-HT sub(6 receptor antagonistic structure-activity relationship are disclosed…”
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Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT6 receptor antagonists by IVACHTCHENKO, Alexandre V, GOLOVINA, Elena S, KADIEVA, Madina G, KYSIL, Volodymyr M, MITKIN, Oleg D, TKACHENKO, Sergey E, OKUN, Ilya

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Synthesis and structure-activity relationship (SAR) of (5,7-disubstituted 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidin-2-yl)-methylamines as potent serotonin 5-HT(6) receptor (5-HT(6)R) antagonists by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Kysil, Volodymyr M, Mitkin, Oleg D, Tkachenko, Sergey E, Okun, Ilya M

“…Syntheses, biological evaluation as 5-HT(6) receptor (5-HT(6)R) antagonists, and structure-activity relationships for a series of novel 5,7-disubstituted…”
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2-Substituted 5,6-dimethyl-3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines: New series of highly potent and specific serotonin 5-HT6 receptor antagonists by IVACHTCHENKO, Alexandre V, GOLOVINA, Elena S, KADIEVA, Madina G, KORYAKOVA, Angela G, MITKIN, Oleg D, TKACHENKO, Sergey E, KYSIL, Volodymyr M, OKUN, Ilya

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Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5- a ]quinazolines: Selective Serotonin 5-HT 6 Receptor Antagonists by Ivachtchenko, Alexandre V., Golovina, Elena S., Kadieva, Madina G., Koryakova, Angela G., Kovalenko, Sergiy M., Mitkin, Oleg D., Okun, Ilya M., Ravnyeyko, Irina M., Tkachenko, Sergey E., Zaremba, Oleg V.

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Solution phase parallel synthesis of substituted 3-phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: selective serotonin 5-HT(6) receptor antagonists by Ivachtchenko, Alexandre V, Golovina, Elena S, Kadieva, Madina G, Koryakova, Angela G, Kovalenko, Sergiy M, Mitkin, Oleg D, Okun, Ilya M, Ravnyeyko, Irina M, Tkachenko, Sergey E, Zaremba, Oleg V

“…Here we present the solution phase parallel synthesis of a combinatorial library consisting of 776 new substituted…”
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