Search Results - "Kadie, Carl M."
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HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins
Published in PloS one (19-08-2009)“…Despite the extensive genetic diversity of HIV-1, viral evolution in response to immune selective pressures follows broadly predictable mutational patterns…”
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Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection
Published in Journal of Virology (01-11-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Gag-Protease-Mediated Replication Capacity in HIV-1 Subtype C Chronic Infection: Associations with HLA Type and Clinical Parameters
Published in Journal of Virology (01-10-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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FaST linear mixed models for genome-wide association studies
Published in Nature methods (01-10-2011)“…An algorithm for linear mixed models substantially reduces memory usage and run time for genome-wide association studies. The improved algorithm scales…”
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Reduced Replication Capacity of NL4-3 Recombinant Viruses Encoding Reverse Transcriptase–Integrase Sequences From HIV-1 Elite Controllers
Published in Journal of acquired immune deficiency syndromes (1999) (01-02-2011)“…BACKGROUND:Identifying viral and host determinants of HIV-1 elite control may help inform novel therapeutic and/or vaccination strategies. Previously, we…”
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Improved linear mixed models for genome-wide association studies
Published in Nature methods (01-06-2012)Get full text
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HIV-1 adaptation to NK-cell-mediated immune pressure
Published in Nature (London) (04-08-2011)“…Natural killer cells and the control of HIV-1 Recent work has suggested that natural killer (NK) cells contribute to the control of HIV-1 infection through…”
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A powerful and efficient set test for genetic markers that handles confounders
Published in Bioinformatics (15-06-2013)“…Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important…”
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The benefits of selecting phenotype-specific variants for applications of mixed models in genomics
Published in Scientific reports (09-05-2013)“…Applications of linear mixed models (LMMs) to problems in genomics include phenotype prediction, correction for confounding in genome-wide association studies,…”
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An Exhaustive Epistatic SNP Association Analysis on Expanded Wellcome Trust Data
Published in Scientific reports (22-01-2013)“…We present an approach for genome-wide association analysis with improved power on the Wellcome Trust data consisting of seven common phenotypes and shared…”
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CORRIGENDUM: An Exhaustive Epistatic SNP Association Analysis on Expanded Wellcome Trust Data
Published in Scientific reports (18-02-2013)Get full text
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The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation
Published in Science (American Association for the Advancement of Science) (10-12-2010)“…Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility complex (MHC); however, the basis…”
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Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans
Published in Human molecular genetics (01-10-2012)“…A small proportion of human immunodeficiency virus-1 (HIV-1) infected individuals, termed HIV-1 controllers, suppress viral replication to very low levels in…”
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Correction: Corrigendum: An Exhaustive Epistatic SNP Association Analysis on Expanded Wellcome Trust Data
Published in Scientific reports (18-02-2013)“…We present an approach for genome-wide association analysis with improved power on the Wellcome Trust data consisting of seven common phenotypes and shared…”
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A powerful and efficient set test for genetic markers that handles confounders
Published 08-04-2013“…Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important…”
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