Search Results - "Kadesch, T."

The Notch Intracellular Domain Can Function as a Coactivator for LEF-1 by Ross, David A., Kadesch, Tom

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Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer by Genetta, T, Ruezinsky, D, Kadesch, T

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B-cell-specific DNA binding by an E47 homodimer by Shen, Chun-Pyn, Kadesch, Tom

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Notch signaling: the demise of elegant simplicity by Kadesch, Tom

“…Notch signaling can be viewed as an elegantly simple pathway that begins when the Notch receptor binds ligand, and ends when the Notch intracellular domain…”
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Tissue-specific gene activation by MyoD: determination of specificity by cis-acting repression elements by Weintraub, H, Genetta, T, Kadesch, T

“…MyoD is a muscle-specific transcriptional activator; E12 is a B-cell activator. An IgH enhancer is activated almost 100-fold by E12 but not at all by Myo; an…”
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Structure of the human liver/bone/kidney alkaline phosphatase gene by Weiss, M J, Ray, K, Henthorn, P S, Lamb, B, Kadesch, T, Harris, H

“…In man, there are multiple forms of alkaline phosphatase encoded by at least three homologous genes: placental, intestinal, and liver/bone/kidney. This report…”
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E47 activates the Ig‐heavy chain and TdT loci in non‐B cells by Choi, J. K., Shen, C. P., Radomska, H. S., Eckhardt, L. A., Kadesch, T.

“…The E2A proteins, E12 and E47, are basic helix‐loop‐helix (bHLH) proteins essential for the B‐cell lineage. Initially identified as immunoglobulin…”
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Phosphorylation of E47 as a potential determinant of B-cell-specific activity by Sloan, Steven R., Shen, Chun-Pyn, McCarrick-Walmsley, Ruth, Kadesch, Tom

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The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity by BECKMANN, H, KADESCH, T

“…TFE3 is a DNA-binding protein that activates transcription through the muE3 site of the immunoglobulin heavy-chain enhancer. Its amino acid sequence reveals…”
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DNA binding site preferences and transcriptional activation properties of the Arabidopsis transcription factor GBF1 by Schindler, U, Terzaghi, W, Beckmann, H, Kadesch, T, Cashmore, A.R

“…The G-box is a cis-acting element found within the promoters of many plant genes where it mediates expression in response to a variety of different stimuli…”
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Expression of a Human Placental Alkaline Phosphatase Gene in Transfected Cells: Use as a Reporter for Studies of Gene Expression by Henthorn, Paula, Zervos, Paula, Raducha, Michael, Harris, Harry, Kadesch, Tom

“…The human placental alkaline phosphatase gene has been cloned and reintroduced into mammalian cells. When a plasmid carrying the gene under control of the…”
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Modulation of the IgH enhancer's cell type specificity through a genetic switch by RUEZINSKY, D, BECKMANN, H, KADESCH, T

“…Using defined regions of the immunoglobulin heavy-chain enhancer linked to minimal promoters and cDNAs that encode the two helix-loop-helix transcription…”
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Selective utilization of basic helix-loop-helix-leucine zipper proteins at the immunoglobulin heavy-chain enhancer by Carter, Robert S., Ordentlich, Peter, Kadesch, Tom

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Effects of the position of the simian virus 40 enhancer on expression of multiple transcription units in a single plasmid by KADESCH, T, BERG, P

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Sequence and characterization of the human intestinal alkaline phosphatase gene by Henthorn, P S, Raducha, M, Kadesch, T, Weiss, M J, Harris, H

“…At least four genes encode the human alkaline phosphatases (ALPs). The genes encoding three of these proteins (intestinal, placental, and placental-like ALPs),…”
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Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development by WILSON, R. B, KILEDJIAN, M, CHUN-PYN SHEN, BENEZRA, R, ZWOLLO, P, DYMECKI, S. M, DESIDERIO, S. V, KADESCH, T

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Consequences of heteromeric interactions among helix-loop-helix proteins by KADESCH, T

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Notch Signaling: A Dance of Proteins Changing Partners by Kadesch, Tom

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Post-transcriptional regulation of the human liver/bone/kidney alkaline phosphatase gene by KILDJIAN, M, KADESCH, T

“…Osteoblasts express high levels of liver/bone/kidney alkaline phosphatase (LBK AP), an enzyme critical for bone formation. Other tissues and cell types…”
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The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription by LI-KUO SU, KADESCH, T

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