Search Results - "Kadenbach, Bernhard"

Complex IV – The regulatory center of mitochondrial oxidative phosphorylation by Kadenbach, Bernhard

“…•Cytochrome oxidase (COX), the regulatory center of OXPHOS.•“ATP-inhibition” of COX prevents ROS formation.•Stress abolishes inhibition of COX by Ca2+…”
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Regulation of Mammalian 13-Subunit Cytochrome c Oxidase and Binding of other Proteins: Role of NDUFA4 by Kadenbach, Bernhard

“…Cytochrome c oxidase (CcO) is the final oxygen accepting enzyme complex (complex IV) of the mitochondrial respiratory chain. In contrast to the other complexes…”
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The subunit composition and function of mammalian cytochrome c oxidase by Kadenbach, Bernhard, Hüttemann, Maik

“…Cytochrome c oxidase (COX) from mammals and birds is composed of 13 subunits. The three catalytic subunits I-III are encoded by mitochondrial DNA, the ten…”
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Stress-mediated generation of deleterious ROS in healthy individuals - role of cytochrome c oxidase by Ramzan, Rabia, Vogt, Sebastian, Kadenbach, Bernhard

“…Psychosocial stress is known to cause an increased incidence of coronary heart disease. In addition, multiple other diseases like cancer and diabetes mellitus…”
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Intrinsic and extrinsic uncoupling of oxidative phosphorylation by Kadenbach, Bernhard

“…This article reviews parameters of extrinsic uncoupling of oxidative phosphorylation (OxPhos) in mitochondria, based on induction of a proton leak across the…”
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New extension of the Mitchell Theory for oxidative phosphorylation in mitochondria of living organisms by Kadenbach, Bernhard, Ramzan, Rabia, Wen, Li, Vogt, Sebastian

“…The Mitchell Theory implies the proton motive force Δp across the inner mitochondrial membrane as the energy-rich intermediate of oxidative phosphorylation. Δp…”
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The role of mitochondrial membrane potential in ischemic heart failure by Kadenbach, Bernhard, Ramzan, Rabia, Moosdorf, Rainer, Vogt, Sebastian

“…The molecular events occurring during myocardial infarction and cardioprotection are described with an emphasis on the changes of the mitochondrial membrane…”
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Multiple Mechanisms Regulate Eukaryotic Cytochrome C Oxidase by Ramzan, Rabia, Kadenbach, Bernhard, Vogt, Sebastian

“…Cytochrome c oxidase (COX), the rate-limiting enzyme of mitochondrial respiration, is regulated by various mechanisms. Its regulation by ATP (adenosine…”
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Mitochondrial respiration and membrane potential are regulated by the allosteric ATP-inhibition of cytochrome c oxidase by Ramzan, Rabia, Staniek, Katrin, Kadenbach, Bernhard, Vogt, Sebastian

“…This paper describes the problems of measuring the allosteric ATP-inhibition of cytochrome c oxidase (CcO) in isolated mitochondria. Only by using the…”
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Phosphorylation and Kinetics of Mammalian Cytochrome c Oxidase by Helling, Stefan, Vogt, Sebastian, Rhiel, Annika, Ramzan, Rabia, Wen, Li, Marcus, Katrin, Kadenbach, Bernhard

“…The influence of protein phosphorylation on the kinetics of cytochrome c oxidase was investigated by applying Western blotting, mass spectrometry, and kinetic…”
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The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases by Kadenbach, Bernhard, Arnold, Susanne, Lee, Icksoo, Hüttemann, Maik

“…Apoptotic cell death can occur by two different pathways. Type 1 is initiated by the activation of death receptors (Fas, TNF-receptor-family) on the plasma…”
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Cholate Disrupts Regulatory Functions of Cytochrome c Oxidase by Ramzan, Rabia, Napiwotzki, Jörg, Weber, Petra, Kadenbach, Bernhard, Vogt, Sebastian

“…Cytochrome c oxidase (CytOx), the oxygen-accepting and rate-limiting enzyme of mitochondrial respiration, binds with 10 molecules of ADP, 7 of which are…”
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The allosteric ATP-inhibition of cytochrome c oxidase activity is reversibly switched on by cAMP-dependent phosphorylation by Bender, Elisabeth, Kadenbach, Bernhard

“…In previous studies the allosteric inhibition of cytochrome c oxidase at high intramitochondrial ATP/ADP-ratios via binding of the nucleotides to the matrix…”
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Cytochrome c Oxidase and the Regulation of Oxidative Phosphorylation by Ludwig, Bernd, Bender, Elisabeth, Arnold, Susanne, Hüttemann, Maik, Lee, Icksoo, Kadenbach, Bernhard

“…Life of higher organisms is essentially dependent on the efficient synthesis of ATP by oxidative phosphorylation in mitochondria. An important and as yet…”
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New control of mitochondrial membrane potential and ROS formation--a hypothesis by Lee, I, Bender, E, Arnold, S, Kadenbach, B

“…A new control of mitochondrial membrane potential delta(psi)m and formation of reactive oxygen species (ROS) is presented, based on allosteric ATP-inhibition…”
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Regulation of mitochondrial respiration and ATP synthesis via cytochrome c oxidase by Kadenbach, Bernhard

“…Cytochrome c oxidase (COX) represents the main oxygen acceptor for respiration of aerobic organisms. The energy of respiration is stored via oxidative…”
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Regulation of cytochrome c oxidase contributes to health and optimal life by Kadenbach, Bernhard

“…The generation of cellular energy in the form of ATP occurs mainly in mitochondria by oxidative phosphorylation. Cytochrome c oxidase (CytOx), the oxygen…”
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Regulation of the H +/e − stoichiometry of cytochrome c oxidase from bovine heart by intramitochondrial ATP/ADP ratios by Frank, Viola, Kadenbach, Bernhard

“…This paper describes the effect of intramitochondrial ATP/ADP ratios on the H +/e − stoichiometry of reconstituted cytochrome c oxidase (COX) from bovine…”
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Cell Respiration is Controlled by ATP, an Allosteric Inhibitor of Cytochrome‐c Oxidase by Arnold, Susanne, Kadenbach, Bernhard

“…The activity of cytochrome‐c oxidase, the terminal enzyme of the mitochondria) respiratory chain, is known to be regulated by the substrate pressure, i.e. the…”
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ATP and ADP bind to cytochrome c oxidase and regulate its activity by Napiwotzki, J, Shinzawa-Itoh, K, Yoshikawa, S, Kadenbach, B

“…By equilibrium dialysis of cytochrome c oxidase from bovine heart with [35S]ATPalphaS and [35S]ADPalphaS, seven binding sites for ATP and ten for ADP were…”
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