Search Results - "Kadaba, S"

The streptococcal M protein: a highly versatile molecule by Smeesters, Pierre R, McMillan, David J, Sriprakash, Kadaba S

“…Interaction of the M-protein of group A Streptococcus (GAS) with its numerous host binding partners might assist the bacteria in evading host immune responses…”
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Complement inhibition by Sarcoptes scabiei protects Streptococcus pyogenes - An in vitro study to unravel the molecular mechanisms behind the poorly understood predilection of S. pyogenes to infect mite-induced skin lesions by Swe, Pearl M, Christian, Lindsay D, Lu, Hieng C, Sriprakash, Kadaba S, Fischer, Katja

“…On a global scale scabies is one of the most common dermatological conditions, imposing a considerable economic burden on individuals, communities and health…”
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High-throughput metagenome analysis of the Sarcoptes scabiei internal microbiota and in-situ identification of intestinal Streptomyces sp by Swe, Pearl M., Zakrzewski, Martha, Waddell, Rebecca, Sriprakash, Kadaba S., Fischer, Katja

“…Multiple parasitic arthropods of medical importance depend on symbiotic bacteria. While the link between scabies and secondary bacterial infections causing…”
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Singh's love affair with Australia by Sriprakash, Kadaba S.

“…About 20 years ago, I received a letter from Singh asking me whether collaboration between us in group A streptococcus research is possible, and he expressed…”
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Complications of biliary-enteric anastomoses by Kadaba, R S, Bowers, K A, Khorsandi, S, Hutchins, R R, Abraham, A T, Sarker, S-J, Bhattacharya, S, Kocher, H M

“…INTRODUCTION Biliary-enteric anastomoses are performed for a range of indications and may result in early and late complications. The aim of this study was to…”
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Characterization of an experimental model to determine streptococcal M protein–induced autoimmune cardiac and neurobehavioral abnormalities by Rafeek, Rukshan AM, Hamlin, Adam S, Andronicos, Nicholas M, Lawlor, Craig S, McMillan, David J, Sriprakash, Kadaba S, Ketheesan, Natkunam

“…Group A streptococcal (GAS) infection is associated with a spectrum of autoimmune diseases including acute rheumatic fever/rheumatic heart disease (ARF/RHD)…”
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Group G Streptococcus Induces an Autoimmune Carditis Mediated by Interleukin 17A and Interferon γ in the Lewis Rat Model of Rheumatic Heart Disease by Sikder, Suchandan, Williams, Natasha L, Sorenson, Alanna E, Alim, Md A, Vidgen, Miranda E, Moreland, Nicole J, Rush, Catherine M, Simpson, Robert S, Govan, Brenda L, Norton, Robert E, Cunningham, Madeleine W, McMillan, David J, Sriprakash, Kadaba S, Ketheesan, Natkunam

“…Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune sequelae of group A streptococcal infections. Here we provide experimental…”
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Complement inhibitors from scabies mites promote streptococcal growth--a novel mechanism in infected epidermis? by Mika, Angela, Reynolds, Simone L, Pickering, Darren, McMillan, David, Sriprakash, Kadaba S, Kemp, David J, Fischer, Katja

“…Scabies is highly prevalent in socially disadvantaged communities such as indigenous populations and in developing countries. Generalized itching causes…”
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A longitudinal study of antibody responses to selected host antigens in rheumatic fever and rheumatic heart disease by Surve, Nuzhat Z, Kerkar, Prafulla G, Deshmukh, Chandrahas T, Nadkar, Milind Y, Mehta, Preeti R, Ketheesan, Natkunam, Sriprakash, Kadaba S, Karmarkar, Mohan G

“…Group A streptococci can trigger autoimmune responses that lead to acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Some autoantibodies generated…”
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Reply to Dale and Shulman by Sikder, Suchandan, Rush, Catherine M, Govan, Brenda L, Norton, Robert E, Cunningham, Madeleine W, McMillan, David J, Sriprakash, Kadaba S, Ketheesan, Natkunam

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Requirements for a Robust Animal Model to Investigate the Disease Mechanism of Autoimmune Complications Associated With ARF/RHD by Rafeek, Rukshan A M, Sikder, Suchandan, Hamlin, Adam S, Andronicos, Nicholas M, McMillan, David J, Sriprakash, Kadaba S, Ketheesan, Natkunam

“…The pathogenesis of Acute Rheumatic Fever/Rheumatic Heart Disease (ARF/RHD) and associated neurobehavioral complications including Sydenham's chorea (SC) is…”
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Predicted Coverage and Immuno-Safety of a Recombinant C-Repeat Region Based Streptococcus pyogenes Vaccine Candidate by McNeilly, Celia, Cosh, Samantha, Vu, Therese, Nichols, Jemma, Henningham, Anna, Hofmann, Andreas, Fane, Anne, Smeesters, Pierre R, Rush, Catherine M, Hafner, Louise M, Ketheesan, Natkuman, Sriprakash, Kadaba S, McMillan, David J

“…The C-terminal region of the M-protein of Streptococcus pyogenes is a major target for vaccine development. The major feature is the C-repeat region,…”
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DrsG from Streptococcus dysgalactiae subsp. equisimilis inhibits the antimicrobial peptide LL-37 by Smyth, Danielle, Cameron, Ainslie, Davies, Mark R, McNeilly, Celia, Hafner, Louise, Sriprakash, Kadaba S, McMillan, David J

“…SIC and DRS are related proteins present in only 4 of the >200 Streptococcus pyogenes emm types. These proteins inhibit complement-mediated lysis and/or the…”
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In Search of the Holy Grail: A Specific Diagnostic Test for Rheumatic Fever by McMillan, David J, Rafeek, Rukshan A M, Norton, Robert E, Good, Michael F, Sriprakash, Kadaba S, Ketheesan, Natkunam

“…Current diagnosis of Acute Rheumatic Fever and Rheumatic Heart Disease (ARF/RHD) relies on a battery of clinical observations aided by technologically advanced…”
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Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein by Bauer, Michelle J, Georgousakis, Melina M, Vu, Therese, Henningham, Anna, Hofmann, Andreas, Rettel, Mandy, Hafner, Louise M, Sriprakash, Kadaba S, McMillan, David J

“…Highlights ► Common variant sequences in the C-repeat region of variant M-proteins are identified. ► We express and purify fusion proteins consisting of the…”
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First Description of the Composition and the Functional Capabilities of the Skin Microbial Community Accompanying Severe Scabies Infestation in Humans by Bernigaud, Charlotte, Zakrzewski, Martha, Taylor, Sara, Swe, Pearl M, Papenfuss, Anthony T, Sriprakash, Kadaba S, Holt, Deborah, Chosidow, Olivier, Currie, Bart J, Fischer, Katja

“…Epidemiological studies link infection and impetigo. Scabies mites can promote (Group A ) and infections by breaching the skin barrier and excreting molecules…”
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A Novel Integrative Conjugative Element Mediates Genetic Transfer from Group G Streptococcus to Other β-Hemolytic Streptococci by DAVIES, Mark R, SHERA, Josephine, VAN DOMSELAAR, Gary H, SRIPRAKASH, Kadaba S, MCMILLAN, David J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Group A streptococcal antigen exposed rat model to investigate neurobehavioral and cardiac complications associated with post‐streptococcal autoimmune sequelae by Rafeek, Rukshan A. M., Lobbe, Catherine M., Wilkinson, Ethan C., Hamlin, Adam S., Andronicos, Nicholas M., McMillan, David J., Sriprakash, Kadaba S., Ketheesan, Natkunam

“…Background The neuropsychiatric disorders due to post‐streptococcal autoimmune complications such as Sydenham's chorea (SC) are associated with acute rheumatic…”
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Virulence Profiling of Streptococcus dysgalactiae Subspecies equisimilis Isolated from Infected Humans Reveals 2 Distinct Genetic Lineages That Do Not Segregate with Their Phenotypes or Propensity to Cause Diseases by Davies, Mark R., McMillan, David J., Beiko, Robert G., Barroso, Vanessa, Geffers, Robert, Sriprakash, Kadaba S., Chhatwal, Gursharan S.

“…Background. In spite of the emerging importance of Streptococcus dysgalactiae subspecies equisimilis (human group C streptococci [GCS] and group G streptococci…”
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Seropositivity for Antibodies to DRS-G, a Virulence Factor from Streptococcus dysgalactiae subsp. equisimilis, Is an Independent Risk Factor for Poststreptococcus Glomerulonephritis and Chronic Kidney Disease in Mumbai, India by Hule, Gouri P, Karmarkar, Mohan G, Cameron, Ainslie, Hase, Niwrutti, Khopkar, Uday, Mehta, Preeti R, McNeilly, Celia L, McMillan, David, Sriprakash, Kadaba S

“…The disease spectrum caused by Streptococcus dysgalactiae subsp. equisimilis resembles that of S. pyogenes (group A streptococcus [GAS]). These two bacterial…”
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