Search Results - "Kaczor, Przemyslaw"

α1 Proline 277 Residues Regulate GABAAR Gating through M2-M3 Loop Interaction in the Interface Region by Kaczor, Przemyslaw T., Michałowski, Michał A., Mozrzymas, Jerzy W.

“…Cys-loop receptors are a superfamily of transmembrane, pentameric receptors that play a crucial role in mammalian CNS signaling. Physiological activation of…”
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α 1 Proline 277 Residues Regulate GABA A R Gating through M2-M3 Loop Interaction in the Interface Region by Kaczor, Przemyslaw T, Michałowski, Michał A, Mozrzymas, Jerzy W

“…Cys-loop receptors are a superfamily of transmembrane, pentameric receptors that play a crucial role in mammalian CNS signaling. Physiological activation of…”
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α1 Subunit Histidine 55 at the Interface between Extracellular and Transmembrane Domains Affects Preactivation and Desensitization of the GABAA Receptor by Kaczor, Przemyslaw T, Wolska, Aleksandra D, Mozrzymas, Jerzy W

“…The GABAA receptor is a member of the Cys-loop family and plays a crucial role in the adult mammalian brain inhibition. Although the static structure of this…”
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α 1 Subunit Histidine 55 at the Interface between Extracellular and Transmembrane Domains Affects Preactivation and Desensitization of the GABA A Receptor by Kaczor, Przemyslaw T, Wolska, Aleksandra D, Mozrzymas, Jerzy W

“…The GABA receptor is a member of the Cys-loop family and plays a crucial role in the adult mammalian brain inhibition. Although the static structure of this…”
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Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes by Kaczor, Przemysław, Rakus, Dariusz, Mozrzymas, Jerzy W

“…Gamma aminobutric acid (GABA) is the major inhibitory neurotransmitter in the adult brain and mechanisms of GABAergic inhibition have been intensely…”
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Falcarindiol Allosterically Modulates GABAergic Currents in Cultured Rat Hippocampal Neurons by Wyrembek, Paulina, Negri, Roberto, Kaczor, Przemysław, Czyżewska, Marta, Appendino, Giovanni, Mozrzymas, Jerzy Wladyslaw

“…Falcarindiol (1), a C-17 polyacetylenic diol, shows a pleiotropic profile of bioactivity, but the mechanism(s) underlying its actions are largely unknown…”
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The C loop at the orthosteric binding site is critically involved in GABA A receptor gating by Terejko, Katarzyna, Kaczor, Przemysław T, Michałowski, Michał A, Dąbrowska, Agnieszka, Mozrzymas, Jerzy W

“…GABA receptors (GABA Rs) play a crucial role in mammalian adult brain inhibition. The dysfunction of GABAergic drive is related to such disorders as epilepsy,…”
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The C loop at the orthosteric binding site is critically involved in GABAA receptor gating by Terejko, Katarzyna, Kaczor, Przemysław T., Michałowski, Michał A., Dąbrowska, Agnieszka, Mozrzymas, Jerzy W.

“…GABAA receptors (GABAARs) play a crucial role in mammalian adult brain inhibition. The dysfunction of GABAergic drive is related to such disorders as epilepsy,…”
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Key Metabolic Enzymes Underlying Astrocytic Upregulation of GABAergic Plasticity by Kaczor, Przemysław T, Mozrzymas, Jerzy W

“…GABAergic plasticity is recognized as a key mechanism of shaping the activity of the neuronal networks. However, its description is challenging because of…”
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Refer analysis of α1β2γ2 GABA type a receptor suggests a slight phase shift between principal and complementary subunits at the extracellular domain upon channel activation by Mozrzymas, Jerzy W., Michalowski, Michal A., Terejko, Katarzyna, Brodzki, Marek, Kaczor, Przemyslaw

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MOLECULAR PATH OF THE GABA TYPE A RECEPTOR ACTIVATION by Michałowski, Michał A, Terejko, Katarzyna, Kaczor, Przemysław T, Brodzki, Marek, Czyżewska, Marta M, Brzóstowicz, Aleksandra, Kłopotowski, Karol, Mozrzymas, Jerzy W

“…GABA type A receptor, a pentameric ligand gated ion channel, plays a crucial role in inhibition in the brain and its dysfunction may cause various diseases…”
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