Search Results - "Kaczmarek, L K"

Specific and rapid effects of acoustic stimulation on the tonotopic distribution of Kv3.1b potassium channels in the adult rat by Strumbos, J.G, Polley, D.B, Kaczmarek, L.K

“…Abstract Recent studies have demonstrated that total cellular levels of voltage-gated potassium channel subunits can change on a time scale of minutes in acute…”
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High-frequency firing helps replenish the readily releasable pool of synaptic vesicles by Wang, Lu-Yang, Kaczmarek, Leonard K

“…Synapses in the central nervous system undergo various short- and long-term changes in their strength, but it is often difficult to distinguish whether…”
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Kv1.3 Channel Gene-Targeted Deletion Produces “Super-Smeller Mice” with Altered Glomeruli, Interacting Scaffolding Proteins, and Biophysics by Fadool, D.A, Tucker, K, Perkins, R, Fasciani, G, Thompson, R.N, Parsons, A.D, Overton, J.M, Koni, P.A, Flavell, R.A, Kaczmarek, L.K

“…Mice with gene-targeted deletion of the Kv1.3 channel were generated to study its role in olfactory function. Potassium currents in olfactory bulb mitral cells…”
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Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts by Kanemasa, T, Gan, L, Perney, T M, Wang, L Y, Kaczmarek, L K

“…1. The Shaw-like voltage-activated potassium channel Kv3.1 is expressed in neurons that generate rapid trains of action potentials. By expressing this channel…”
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Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain by Perney, T M, Marshall, J, Martin, K A, Hockfield, S, Kaczmarek, L K

“…1. The gene for a mammalian Shaw K+ channel has recently been cloned and has been shown, by alternative splicing, to give rise to two different transcripts,…”
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Properties and regulation of the minK potassium channel protein by Kaczmarek, L K, Blumenthal, E M

“…The minK gene encodes a protein of 130 amino acids that has a single transmembrane segment and is expressed in many tissues including heart, uterus, and…”
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Prolonged Activation of Mitochondrial Conductances During Synaptic Transmission by Jonas, Elizabeth A., Buchanan, JoAnn, Kaczmarek, Leonard K.

“…Although ion channels have been detected in mitochondria, scientists have not been able to record ion transport in mitochondria of intact cells. A variation of…”
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Modification of delayed rectifier potassium currents by the Kv9.1 potassium channel subunit by Richardson, Frank C, Kaczmarek, Leonard K

“…Within auditory pathways, the intrinsic electrical properties of neurons, and in particular their complement of potassium channels, play a key role in shaping…”
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Stimulation of protein kinase C recruits covert calcium channels in Aplysia bag cell neurons by Strong, J. A, Fox, A. P, Tsien, R. W, Kaczmarek, L. K

“…The modulation of voltage-activated calcium currents by protein kinases provides excitable cells with a mechanism for regulating their electrical behaviour. At…”
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Cyclic AMP induces changes in distribution and transport of organelles within growth cones of Aplysia bag cell neurons by Forscher, P, Kaczmarek, LK, Buchanan, JA, Smith, SJ

“…This report examines cAMP-induced regulation of directed organelle transport in bag cell neuron growth cones using video-enhanced differential interference…”
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Mitochondrial factors with dual roles in death and survival by Cheng, W-C, Berman, S B, Ivanovska, I, Jonas, E A, Lee, S J, Chen, Y, Kaczmarek, L K, Pineda, F, Hardwick, J M

“…At least in mammals, we have some understanding of how caspases facilitate mitochondria-mediated cell death, but the biochemical mechanisms by which other…”
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Mode-switching of a voltage-gated cation channel is mediated by a protein kinase A-regulated tyrosine phosphatase by Wilson, Gisela F, Kaczmarek, Leonard K

“…Tyrosine kinases and tyrosine phosphatases are abundant in central nervous system tissue, yet the role of these enzymes in the modulation of neuronal…”
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The Expression of Two Splice Variants of the Kv3.1 Potassium Channel Gene Is Regulated by Different Signaling Pathways by Liu, Si-qiong J, Kaczmarek, Leonard K

“…The Kv3.1 potassium channel gene gives rise to two different channel proteins, Kv3.1a and Kv3.1b, by alternative splicing of nuclear RNA. During development…”
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Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C by DeRiemer, S. A, Strong, J. A, Albert, K. A, Greengard, P, Kaczmarek, L. K

“…One of the molecular mechanisms capable of regulating the physiological properties of neurones is the phosphorylation of ion channels and other cellular…”
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Localization of the Slack potassium channel in the rat central nervous system by Bhattacharjee, Arin, Gan, Li, Kaczmarek, Leonard K.

“…The Slack gene encodes a voltage‐dependent K+ channel that has a unitary conductance of ∼60 pS. Evidence from heterologous expression studies suggests that…”
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Insulin receptor in Aplysia neurons: characterization, molecular cloning, and modulation of ion currents by Jonas, EA, Knox, RJ, Kaczmarek, LK, Schwartz, JH, Solomon, DH

“…We have isolated the cDNA for a tyrosine kinase receptor that is expressed in the nervous system of Aplysia californica and that is similar to the vertebrate…”
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Ca2+ influx and activation of a cation current are coupled to intracellular Ca2+ release in peptidergic neurons of Aplysia californica by Knox, R J, Jonas, E A, Kao, L S, Smith, P J, Connor, J A, Kaczmarek, L K

“…1. Stimulation of inputs to bag cell neurons in the abdominal ganglion of Aplysia californica causes an increase in their intracellular Ca2+ concentration…”
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Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator by MARSHALL, J, MARTIN, K. A, PICCIOTTO, M, HOEKFIELD, S, NAIRN, A. C, KACZMAREK, L. K

“…Chloride channels in the apical plasma membrane of cells in the dogfish rectal gland have served as a model system for the study of regulation of chloride flux…”
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Slick (Slo2.1), a Rapidly-Gating Sodium-Activated Potassium Channel Inhibited by ATP by Bhattacharjee, Arin, Joiner, William J, Wu, Meilin, Yang, Youshan, Sigworth, Fred J, Kaczmarek, Leonard K

“…Neuronal stressors such as hypoxia and firing of action potentials at very high frequencies cause intracellular Na+ to rise and ATP to be consumed faster than…”
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Transient changes in intracellular calcium associated with a prolonged increase in excitability in neurons of Aplysia californica by Fisher, T E, Levy, S, Kaczmarek, L K

“…1. Transient stimulation of an afferent input to the bag cell neurons of Aplysia californica triggers a 30-min period of spontaneous firing termed the…”
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