Search Results - "Kachigere B, Harsha"

Synthesis, characterization and cytotoxicity studies of 1,2,3-triazoles and 1,2,4-triazolo [1,5-a] pyrimidines in human breast cancer cells by Gilandoust, Maryam, Harsha, Kachigere B., Mohan, Chakrabhavi Dhananjaya, Raquib, Ainiah Rushdiana, Rangappa, Shobith, Pandey, Vijay, Lobie, Peter E., Basappa, Rangappa, Kanchugarakoppal S.

“…[Display omitted] •VEGFR signalling is associated with the progression of various malignancies.•1,2,3-Triazoles and 1,2,4-triazolo-pyrimidines were synthesized…”
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Silver nanoparticles synthesized using saponin extract of Simarouba glauca oil seed meal as effective, recoverable and reusable catalyst for reduction of organic dyes by Chikkanayakanahalli Paramesh, Chitrabanu, Halligudra, Guddappa, Gangaraju, Vinay, Sriramoju, Jagadeesh Babu, Shastri, Mahesh, Kachigere B., Harsha, Habbanakuppe D., Preetham, Rangappa, Dinesh, Kanchugarakoppal Subbegowda, Rangappa, Doddakunche Shivaramu, Prasanna

“…Phytochemicals are natural bioactive molecules found in plants which help mankind in treating various diseases. Saponins are one such class of compounds widely…”
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Anti-Cancer Activity of 2,4-Disubstituted Thiophene Derivatives: Dual Inhibitors of Lipoxygenase and Cyclooxygenase by Rakesh, Kodagahalli S, Jagadish, Swamy, Swaroop, Toreshettahally R, Mohan, Chakrabhavi D, Ashwini, Nanjundaswamy, Harsha, Kachigere B, Zameer, Farhan, Girish, Kesturu S, Rangappa, Kanchugarakoppal S

“…2,4-Disubstituted thiophene derivatives were synthesized and assessed for antiinflammatory and anti-cancer activities by targeting two important enzymes of the…”
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Isoxazolyl-urea derivative evokes apoptosis and paraptosis by abrogating the Wnt/β-catenin axis in colon cancer cells by Suresh, Rajaghatta N., Jung, Young Yun, Harsha, Kachigere B., Mohan, Chakrabhavi Dhananjaya, Ahn, Kwang Seok, Rangappa, Kanchugarakoppal S.

“…Deregulated activation of the Wnt/β-catenin pathway is observed in many types of human malignancies including colon cancer. Abrogation of the Wnt/β-catenin…”
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A new isoxazolyl-urea derivative induces apoptosis, paraptosis, and ferroptosis by modulating MAPKs in pancreatic cancer cells by Jung, Young Yun, Suresh, Rajaghatta N., Mohan, Chakrabhavi Dhananjaya, Harsha, Kachigere B., Shivakumara, Chilkunda Sannaiah, Rangappa, Kanchugarakoppal S., Ahn, Kwang Seok

“…MAPK pathway regulates the major events including cell division, cell death, migration, invasion, and angiogenesis. Small molecules that modulate the MAPK…”
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Microwave assisted one-pot access to pyrazolo quinolinone and tetrahydroisoxazolo quinolinone derivatives via T3P®-DMSO catalysed tandem oxidative–condensation reaction by Gowda, Darshini, Harsha, Kachigere B., Shalini, Veeresha Gowda, Rangappa, Shobith, Rangappa, Kanchugarakoppal S.

“…A new approach for the synthesis of two important annulated pyrazolo quinolinone and tetrahydroisoxazolo quinolinone derivatives from multicomponent reactions…”
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A new triazolyl‐indolo‐quinoxaline induces apoptosis in gastric cancer cells by abrogating the STAT3/5 pathway through upregulation of PTPεC by Suresh, Rajaghatta N., Jung, Young Y., Mohan, Chakrabhavi D., Gowda, Shalini V., Harsha, Kachigere B., Mantelingu, Kempegowda, Sethi, Gautam, Ahn, Kwang S., Rangappa, Kanchugarakoppal S.

“…Signal transducer and activator of transcription 3 (STAT3) and STAT5 are the transcription factors that have been studied extensively in relevance to the…”
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A new 1,2,3-triazole-indirubin hybrid suppresses tumor growth and pulmonary metastasis by mitigating the HGF/c-MET axis in hepatocellular carcinoma by Gowda, Shalini V., Kim, Na Young, Harsha, Kachigere B., Gowda, Darshini, Suresh, Rajaghatta N., Deivasigamani, Amudha, Mohan, Chakrabhavi Dhananjaya, Hui, Kam Man, Sethi, Gautam, Ahn, Kwang Seok, Rangappa, Kanchugarakoppal S.

“…[Display omitted] •A new triazole-indirubin (CRI9) reduced growth of hepatocellular carcinoma cells.•CRI9 decreased the HGF-induced phosphorylation of tyrosine…”
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T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols by Sharath Kumar, Kothanahally S., Swaroop, Toreshettahally R., Harsha, Kachigere B., Narasimhamurthy, Kereyagalahally H., Rangappa, Kanchugarakoppal S.

“…R1, R2=H/Alkyl/Aryl/Heteroaryl and R3=Aryl/Heteroaryl. Propylphosphonic anhydride (T3P®)-DMSO mediated oxidation of alcohols to carbonyl compounds and their…”
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Three closely related 4,5,6,7‐tetrahydro‐1H‐pyrazolo[4,3‐c]pyridines: synthesis, molecular conformations and hydrogen bonding in zero, one and two dimensions by Sagar, Belakavadi K., Harsha, Kachigere B., Yathirajan, Hemmige S., Rangappa, Kanchugarakoppal S., Rathore, Ravindranath S., Glidewell, Christopher

“…In each of 1‐(4‐fluorophenyl)‐5‐methylsulfonyl‐3‐[4‐(trifluoromethyl)phenyl]‐4,5,6,7‐tetrahydro‐1H‐pyrazolo[4,3‐c]pyridine, C21H19F4N3O2S, (I),…”
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Microwave assisted one-pot access to pyrazolo quinolinone and tetrahydroisoxazolo quinolinone derivatives T3P®-DMSO catalysed tandem oxidativecondensation reaction by Gowda, Darshini, Harsha, Kachigere B, Shalini, Veeresha Gowda, Rangappa, Shobith, Rangappa, Kanchugarakoppal S

“…A new approach for the synthesis of two important annulated pyrazolo quinolinone and tetrahydroisoxazolo quinolinone derivatives from multicomponent reactions…”
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Novel quinoline-4-carboxamide derivatives potentiates apoptosis by targeting PDK1 to overcome chemo-resistance in colorectal cancer: Theoretical and experimental results by V, Shalini, N, Priyadarshini A, Kachigere B, Harsha, D C, Vinay Kumar, Gowda, Darshini, B S, Chethan, M Srinivasa, Sudhanva, Rangappa, Shobith, Rangappa, Kanchugarakoppal S

“…A series of novel N,2-diphenyl-6-(aryl/heteroaryl)quinoline-4-carboxamide derivatives were designed and synthesized using the Suzuki coupling reaction and…”
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An Easy and Efficient Method for the Synthesis of Quinoxalines Using Recyclable and Heterogeneous Nanomagnetic‐Supported Acid Catalyst under Solvent‐Free Condition by Harsha, Kachigere B., Rangappa, Shobith, Preetham, Habbanakuppe D., Swaroop, Toreshettahally R., Gilandoust, Maryam, Rakesh, Kodgahally S., Rangappa, Kanchugarakoppal S.

“…Synthesis of quinoxalines from o‐phenylenediamines (o‐PDs) with electronically diversified 1,2‐diketones and α‐bromoketones via simple cyclocondensation…”
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Synthesis and in vitro anti-proliferative studies of new 2-(arylmethylthio)-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-ols by Harsha, Kachigere B., Swaroop, Toreshettahally R., Roopashree, Rangaswamy, Jagadish, Swamy, Rangappa, Kanchugarakoppal S.

“…Synthesis of a series of 2-(arylmethylthio)-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol and their cytotoxic activity on HCT-116 and A-549 cell lines using MTT…”
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Synthesis and in vitro anti-proliferative studies of new 2-(arylmethylthio)-6-ethyl-7 H -pyrrolo[2,3-d]pyrimidin-4-ols by Harsha, Kachigere B., Swaroop, Toreshettahally R., Roopashree, Rangaswamy, Jagadish, Swamy, Rangappa, Kanchugarakoppal S.

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Three closely related 4,5,6,7-tetrahydro-1 H -pyrazolo[4,3- c ]pyridines: synthesis, molecular conformations and hydrogen bonding in zero, one and two dimensions by Sagar, Belakavadi K., Harsha, Kachigere B., Yathirajan, Hemmige S., Rangappa, Kanchugarakoppal S., Rathore, Ravindranath S., Glidewell, Christopher

“…In each of 1-(4-fluorophenyl)-5-methylsulfonyl-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1 H -pyrazolo[4,3- c ]pyridine, C 21 H 19 F 4 N 3 O 2 S, (I),…”
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