Search Results - "Kacena, Melissa A"

The loss of STAT3 in mature osteoclasts has detrimental effects on bone structure by Davidson, Rebecca K., Himes, Evan R., Takigawa, Shinya, Chen, Andy, Horn, M. Ryne, Meijome, Tomas, Wallace, Joseph M., Kacena, Melissa A., Yokota, Hiroki, Nguyen, Andrew V., Li, Jiliang

“…Signal Transducer and Activator of Transcription 3 (STAT3) has recently been shown to be involved in bone development and has been implicated in bone diseases,…”
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Editorial: Impaired bone healing due to bone disuse and osteometabolic disorders by Zamarioli, Ariane, Kacena, Melissa A, Volpon, José B

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Neonatal Osteomacs and Bone Marrow Macrophages Differ in Phenotypic Marker Expression and Function by Mohamad, Safa F, Gunawan, Andrea, Blosser, Rachel, Childress, Paul, Aguilar‐Perez, Alexandra, Ghosh, Joydeep, Hong, Jung Min, Liu, Jianyun, Kanagasabapathy, Deepa, Kacena, Melissa A, Srour, Edward F, Bruzzaniti, Angela

“…ABSTRACT Osteomacs (OM) are specialized bone‐resident macrophages that are a component of the hematopoietic niche and support bone formation. Also located in…”
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Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow by Clinkenbeard, Erica L, Hanudel, Mark R, Stayrook, Keith R, Appaiah, Hitesh Nidumanda, Farrow, Emily G, Cass, Taryn A, Summers, Lelia J, Ip, Colin S, Hum, Julia M, Thomas, Joseph C, Ivan, Mircea, Richine, Briana M, Chan, Rebecca J, Clemens, Thomas L, Schipani, Ernestina, Sabbagh, Yves, Xu, Linlin, Srour, Edward F, Alvarez, Marta B, Kacena, Melissa A, Salusky, Isidro B, Ganz, Tomas, Nemeth, Elizabeta, White, Kenneth E

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IL-34 exacerbates pathogenic features of Alzheimer’s disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice by Ho, Anny, Ngala, Bidii, Yamada, Chiaki, Garcia, Christopher, Duarte, Carolina, Akkaoui, Juliet, Ciolac, Dumitru, Nusbaum, Amilia, Kochen, William, Efremova, Daniela, Groppa, Stanislav, Nathanson, Lubov, Bissel, Stephanie, Oblak, Adrian, Kacena, Melissa A., Movila, Alexandru

“…Hallmark features of Alzheimer’s disease (AD) include elevated accumulation of aggregated Aβ40 and Aβ42 peptides, hyperphosphorylated Tau (p-Tau), and…”
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Soluble Immune Checkpoints Are Dysregulated in COVID-19 and Heavy Alcohol Users With HIV Infection by Li, Wei, Syed, Fahim, Yu, Richard, Yang, Jing, Xia, Ying, Relich, Ryan F, Russell, Patrick M, Zhang, Shanxiang, Khalili, Mandana, Huang, Laurence, Kacena, Melissa A, Zheng, Xiaoqun, Yu, Qigui

“…Immune checkpoints (ICPs) consist of paired receptor-ligand molecules that exert inhibitory or stimulatory effects on immune defense, surveillance, regulation,…”
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SARS-CoV-2 from COVID-19 Patients in the Republic of Moldova: Whole-Genome Sequencing Results by Morozov, Alexandr, Nirca, Vadim, Victorova, Anna, Poppert, Sven, Frickmann, Hagen, Yamada, Chiaki, Kacena, Melissa A, Rata, Sergiu, Movila, Alexandru

“…Since the onset of the COVID-19 pandemic, no viral genome sequences of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) have been documented…”
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No pain, no gain: Will migraine therapies increase bone loss and impair fracture healing? by Kacena, Melissa A., White, Fletcher A.

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Vibration therapy as an effective approach to improve bone healing in diabetic rats by Campos, Maysa S., Volpon, José B., Ximenez, João Paulo B., Franttini, Ana Paula, Dalloul, Christopher E., Sousa-Neto, Manoel D., Silva, Raquel A., Kacena, Melissa A., Zamarioli, Ariane

“…Objective To investigate the effects of vibration therapy on fracture healing in diabetic and non-diabetic rats. Methods 148 rats underwent fracture surgery…”
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Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification by Williams, Justin N, Kambrath, Anuradha Valiya, Patel, Roshni B, Kang, Kyung Shin, Mével, Elsa, Li, Yong, Cheng, Ying‐Hua, Pucylowski, Austin J, Hassert, Mariah A, Voor, Michael J, Kacena, Melissa A, Thompson, William R, Warden, Stuart J, Burr, David B, Allen, Matthew R, Robling, Alexander G, Sankar, Uma

“…ABSTRACT Approximately 10% of all bone fractures do not heal, resulting in patient morbidity and healthcare costs. However, no pharmacological treatments are…”
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Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins by Li, Kexin, Huo, Qingji, Dimmitt, Nathan H, Qu, Guofan, Bao, Junjie, Pandya, Pankita H, Saadatzadeh, M Reza, Bijangi-Vishehsaraei, Khadijeh, Kacena, Melissa A, Pollok, Karen E, Lin, Chien-Chi, Li, Bai-Yan, Yokota, Hiroki

“…Osteosarcoma (OS) is the common primary bone cancer that affects mostly children and young adults. To augment the standard-of-care chemotherapy, we examined…”
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Systemic effects of BMP2 treatment of fractures on non-injured skeletal sites during spaceflight by Zamarioli, Ariane, Adam, Gremah, Maupin, Kevin A., Childress, Paul J., Brinker, Alexander, Ximenez, Joao P. B., Chakraborty, Nabarun, Gautam, Aarti, Hammamieh, Rasha, Kacena, Melissa A.

“…Unloading associated with spaceflight results in bone loss and increased fracture risk. Bone morphogenetic protein 2 (BMP2) is known to enhance bone formation,…”
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Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma by Xu, Linlin, Mohammad, Khalid S, Wu, Hao, Crean, Colin, Poteat, Bradley, Cheng, Yinghua, Cardoso, Angelo A, Machal, Christophe, Hanenberg, Helmut, Abonour, Rafat, Kacena, Melissa A, Chirgwin, John, Suvannasankha, Attaya, Srour, Edward F

“…Multiple myeloma is incurable once osteolytic lesions have seeded at skeletal sites, but factors mediating this deadly pathogenic advance remain poorly…”
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The Changing Balance Between Osteoblastogenesis and Adipogenesis in Aging and its Impact on Hematopoiesis by Bethel, Monique, Chitteti, Brahmananda R., Srour, Edward F., Kacena, Melissa A.

“…Osteoblasts (OBs) and adipocytes (APs) share a common mesenchymal ancestor. It is now clear that mesenchymal stem cell (MSC) maturation along the OB lineage…”
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CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche by Chitteti, Brahmananda Reddy, Kobayashi, Michihiro, Cheng, Yinghua, Zhang, Huajia, Poteat, Bradley A., Broxmeyer, Hal E., Pelus, Louis M., Hanenberg, Helmut, Zollman, Amy, Kamocka, Malgorzata M., Carlesso, Nadia, Cardoso, Angelo A., Kacena, Melissa A., Srour, Edward F.

“…We previously showed that immature CD166+ osteoblasts (OB) promote hematopoietic stem cell (HSC) function. Here, we demonstrate that CD166 is a functional HSC…”
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Bibliometric Analysis of the English Musculoskeletal Literature over the Last 30 Years by Loder, Randall T., Kacena, Melissa A., Ogbemudia, Blessing, Ngwe, Hervé Nonga, Aasar, Abdul, Ninad, Nehal, Mufti, Osama, Gunderson, Zachary, Whipple, Elizabeth C.

“…Publication and authorship are important in academia for career advancement, obtaining grants, and improved patient care. There has been a recent interest in…”
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Bone loss with aging is independent of gut microbiome in mice by You, Xiaomeng, Yan, Jing, Herzog, Jeremy, Nobakhti, Sabah, Campbell, Ross, Hoke, Allison, Hammamieh, Rasha, Sartor, R. Balfour, Shefelbine, Sandra, Kacena, Melissa A, Chakraborty, Nabarun, Charles, Julia F

“…Emerging evidence suggests a significant role of gut microbiome in bone health. Aging is well recognized as a crucial factor influencing the gut microbiome. In…”
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Murine Gut Microbiome Meta-analysis Reveals Alterations in Carbohydrate Metabolism in Response to Aging by You, Xiaomeng, Dadwal, Ushashi C, Lenburg, Marc E, Kacena, Melissa A, Charles, Julia F

“…Compositional and functional alterations to the gut microbiota during aging are hypothesized to potentially impact our health. Thus, determining aging-specific…”
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Hierarchical organization of osteoblasts reveals the significant role of CD166 in hematopoietic stem cell maintenance and function by Chitteti, Brahmananda R, Cheng, Ying-Hua, Kacena, Melissa A, Srour, Edward F

“…Abstract The role of osteoblasts (OB) in maintaining hematopoietic stem cells (HSC) in their niche is well elucidated, but the exact definition, both…”
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Bibliometric and authorship trends over a 30 year publication history in two representative US sports medicine journals by Dynako, Joseph, Owens, Garrett W., Loder, Randall T., Frimpong, Tony, Gerena, Rolando Gabriel, Hasnain, Fawaz, Snyder, Dayton, Freiman, Serena, Hart, Kyle, Kacena, Melissa A., Whipple, Elizabeth C.

“…Bibliometric studies are important to understand changes and improvement opportunities in academia. This study compared bibliometric trends for two major…”
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