Primary adenoid cystic carcinoma of the trachea: a report of two cases and literature review

Adenoid cystic carcinoma (ACC) of the trachea is rare, it represents 1% of all respiratory tract cancers. It's generally considered as a slow-growing, with pronlonged clinical course. Most patients present with dyspnea, and the symptoms often mimic those of asthma or chronic bronchitis Surgical...

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Bibliographic Details
Published in:	The Pan African medical journal Vol. 19; no. 32; p. 32
Main Authors:	El Marjany, Mohammed, Arsalane, Adil, Sifat, Hassan, Andaloussi, Khalid, Oukabli, Mohamed, Hadadi, Khalid, Kabiri, El Hassan, Mansouri, Hamid
Format:	Journal Article
Language:	English
Published:	Uganda The African Field Epidemiology Network 2014 The Pan African Medical Journal
Subjects:	adenoid cystic carcinoma Carcinoma, Adenoid Cystic - pathology Carcinoma, Adenoid Cystic - therapy Case Report Dyspnea - etiology Female Follow-Up Studies Humans Male Middle Aged Neoplasm Recurrence, Local radiotherapy Radiotherapy, Adjuvant - methods trachea Tracheal Neoplasms - pathology Tracheal Neoplasms - therapy tracheal resection radiotherapy tracheal resection trachea Adenoid cystic carcinoma
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Summary:	Adenoid cystic carcinoma (ACC) of the trachea is rare, it represents 1% of all respiratory tract cancers. It's generally considered as a slow-growing, with pronlonged clinical course. Most patients present with dyspnea, and the symptoms often mimic those of asthma or chronic bronchitis Surgical resection is the mainstay of treatment often combined to radiotherapy because of close surgical margins. When surgery isn't possible, most tumors respond to radiotherapy alone wich often results in long periods of remission We report two cases of primary ACC of trachea: a 49 year old male presented a distal unresectable tracheal ACC treated with chemo-radiotherapy who developed a recurrence and died 7 years after the diagnosis. And a 50 years old female with a proximal tracheal tumor treated by surgical resection and end- to- end anastomosis followed by adjuvant radiotherapy. At 10 months follow-up, our patient shows no evidence of disease with negative histological findings.
Bibliography:	ObjectType-Case Study-3 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Review-1 ObjectType-Feature-5 ObjectType-Report-2 ObjectType-Article-4
ISSN:	1937-8688 1937-8688
DOI:	10.11604/pamj.2014.19.32.4878