Search Results - "Kabilova, T. O."
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Targeted Delivery of Nucleic Acids by Folate-Containing Liposomes into KB-3-1 and HEK 293 Cells
Published in Russian journal of bioorganic chemistry (01-11-2019)“…Targeted cationic liposomes containing folate lipoconjugates with spacer groups of various lengths and natures were prepared; their physicochemical…”
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Tumor-Suppressing, Immunostimulating, and Hepatotoxic Effects of Immunostimulatory RNA in Combination with Dacarbazine in a Murine Melanoma Model
Published in Molecular biology (New York) (01-03-2020)“…Melanoma is one of the most aggressive tumors and is accompanied by the induction of local and systemic inflammatory responses. Combinations of…”
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Silencing of c-myc Expression in Tumor Cells by siRNA
Published in Nucleosides, nucleotides & nucleic acids (31-12-2004)“…Suppression of c-myc protooncogene expression in KB-3-1 cells by siRNA was investigated. The siRNA duplex targeted to the exon 3 of c-myc mRNA was prepared by…”
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4
Polycationic amphiphiles based on triethylenetetramine and their transfection efficacy
Published in Russian journal of bioorganic chemistry (01-09-2017)“…Novel polycationic amphiphiles derived from triethylenetetramine, a spermine analogue, containing cholesterol or dialkylglycerol residues as hydrophilic…”
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Impact of chemical modifications in the structure of isRNA on its antiproliferative and immunostimulatory properties
Published in Russian journal of bioorganic chemistry (2017)“…Short double-stranded RNAs, depending on their structure, sequence, and the method of delivery to cells, can activate the system of innate and adaptive…”
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Silencing of c-myc gene expression using enzymatically and chemically synthesized siRNAs
Published in Molecular biology (New York) (01-12-2006)“…Synthetic small interfering RNAs (siRNAs) are of great interest as promising agents for targeted downregulation of gene expression. A study was made of the…”
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Antiproliferative and interferon-inducing activities of unique short double-stranded RNA
Published in Doklady. Biochemistry and biophysics (01-02-2011)“…Currently, the incidence of oncological diseases in the world steadily increases. Conventional surgical and therapeutic schemes of treatment of these diseases,…”
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Myc-family oncogenes as therapeutic targets
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (30-12-2008)Get full text
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Short double-stranded RNA with immunostimulatory activity: sequence dependence
Published in Nucleic acid therapeutics (01-06-2012)“…Small interfering RNAs (siRNA) are able to activate the mammalian innate immune system depending on their structure, sequence, and method of delivery. The…”
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10
Silencing of c-myc gene expression by enzymatically and chemically synthesized siRNAs
Published in Molekuliarnaia biologiia (01-11-2006)“…Small interfering RNAs (siRNA) provide a powerful approach for sequence-specific silencing of gene expression. In the present study we investigated inhibition…”
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Inhibition of human cancer-cell proliferation by long double-stranded RNAs
Published in Oligonucleotides (01-03-2009)“…Three different enzymatically synthesized long double-stranded RNAs (dsRNAs) [448 bp homologous to the third exon of c-myc messenger RNA (mRNA) (dsMyc); 473 bp…”
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Inhibition of human carcinoma and neuroblastoma cell proliferation by anti-c-myc siRNA
Published in Oligonucleotides (01-01-2006)“…Suppression of c-myc proto-oncogene expression by small interfering RNA (siRNA) in human epidermoid carcinoma KB-3-1 and neuroblastoma SK-N-MC cell lines was…”
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