Search Results - "Kabakov, Anatoli Y"
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Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus
Published in Journal of neurophysiology (01-04-2012)“…Transcranial direct current stimulation (tDCS) is a method for modulating cortical excitability by weak constant electrical current that is applied through…”
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2
Ceftriaxone treatment after traumatic brain injury restores expression of the glutamate transporter, GLT-1, reduces regional gliosis, and reduces post-traumatic seizures in the rat
Published in Journal of neurotrauma (15-08-2013)“…Excessive extracellular glutamate after traumatic brain injury (TBI) contributes to excitotoxic cell death and likely to post-traumatic epilepsy. Glutamate…”
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3
Metabolic regulation of endothelial SK channels and human coronary microvascular function
Published in International journal of cardiology (01-08-2020)“…Diabetic (DM) inactivation of small conductance calcium-activated potassium (SK) channels contributes to coronary endothelial dysfunction. However, the…”
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Corrigendum: Three-week-old rabbit ventricular cardiomyocytes as a novel system to study cardiac excitation and EC coupling
Published in Frontiers in physiology (22-02-2023)“…[This corrects the article DOI: 10.3389/fphys.2021.672360.]…”
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5
Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling
Published in Frontiers in physiology (18-11-2021)“…Cardiac arrhythmias significantly contribute to cardiovascular morbidity and mortality. The rabbit heart serves as an accepted model system for studying…”
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6
Catalytically Dead αCaMKII K42M Mutant Acts as a Dominant Negative in the Control of Synaptic Strength
Published in PloS one (23-04-2015)“…During long-term potentiation (LTP) of excitatory synapses, Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is activated by Ca(2+) influx through NMDA…”
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7
Myofibroblast senescence promotes arrhythmogenic remodeling in the aged infarcted rabbit heart
Published in eLife (19-05-2023)“…Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known…”
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8
GLT-1 Transport Stoichiometry Is Constant at Low and High Glutamate Concentrations when Chloride Is Substituted by Gluconate
Published in PloS one (24-08-2015)“…Glutamate is the major excitatory neurotransmitter, but prolonged exposure even at micromolar concentrations causes neuronal death. Extracellular glutamate is…”
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E3 ubiquitin ligase rififylin has yin and yang effects on rabbit cardiac transient outward potassium currents (Ito) and corresponding channel proteins
Published in The Journal of biological chemistry (01-03-2024)“…Genome-wide association studies have reported a correlation between a SNP of the RING finger E3 ubiquitin protein ligase rififylin (RFFL) and QT interval…”
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10
Coronary endothelial dysfunction prevented by small-conductance calcium-activated potassium channel activator in mice and patients with diabetes
Published in The Journal of thoracic and cardiovascular surgery (01-12-2020)“…To investigate coronary endothelial protection of a small-conductance calcium-activated potassium (SK) channel activator against a period of…”
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11
The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2
Published in The Journal of biological chemistry (25-12-2020)“…The QT interval is a recording of cardiac electrical activity. Previous genome-wide association studies identified genetic variants that modify the QT interval…”
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12
Transient Outward K+ Current (Ito) Underlies the Right Ventricular Initiation of Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long-QT Syndrome Type 1
Published in Circulation. Arrhythmia and electrophysiology (01-06-2018)“…BACKGROUND:Sudden death in long-QT syndrome type 1 (LQT1), an inherited disease caused by loss-of-function mutations in KCNQ1, is triggered by early…”
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13
Late I Na Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2
Published in Circulation. Arrhythmia and electrophysiology (01-08-2020)“…Long QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular tachycardias…”
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14
Late INa Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2
Published in Circulation. Arrhythmia and electrophysiology (01-08-2020)“…BACKGROUNDLong QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular…”
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15
Regulation of Glutamate Transport in Developing Rat Oligodendrocytes
Published in The Journal of neuroscience (17-06-2009)“…Glutamate released from synaptic vesicles mediates excitatory neurotransmission by stimulating glutamate receptors. Glutamate transporters maintain low…”
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16
LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor) Regulates Cardiac L-Type Calcium Channels by Modulating NEDD (Neural Precursor Cell Expressed Developmentally Downregulated Protein) 4-1 Ubiquitin Ligase
Published in Circulation. Genomic and precision medicine (01-09-2019)“…The turnover of cardiac ion channels underlying action potential duration is regulated by ubiquitination. Genome-wide association studies of QT interval…”
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17
Evidence for change in current-flux coupling of GLT1 at high glutamate concentrations in rat primary forebrain neurons and GLT1a-expressing COS-7 cells
Published in The European journal of neuroscience (01-07-2009)“…Glutamate is the major excitatory neurotransmitter of the central nervous system and is toxic to neurons even at low concentrations. GLT1, the rodent analog of…”
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18
Catalytically Dead [alpha]CaMKII K42M Mutant Acts as a Dominant Negative in the Control of Synaptic Strength
Published in PloS one (23-04-2015)“…During long-term potentiation (LTP) of excitatory synapses, Ca.sup.2+ /calmodulin-dependent protein kinase II (CaMKII) is activated by Ca.sup.2+ influx through…”
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19
Ubiquitin Ligase Rififylin (RFFL) Has Yin-Yang Effects on Rabbit Cardiac Transient Outward (Ito) Potassium Channels
Published in Biophysical journal (07-02-2020)Get full text
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20
3-Week-Old Rabbit Cardiomyocytes (3wRbCM): A Novel Cellular Model for Studying Cardiac Excitation
Published in Biophysical journal (15-02-2019)Get full text
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