Search Results - "Kabakov, Anatoli Y"

Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus by Kabakov, Anatoli Y, Muller, Paul A, Pascual-Leone, Alvaro, Jensen, Frances E, Rotenberg, Alexander

“…Transcranial direct current stimulation (tDCS) is a method for modulating cortical excitability by weak constant electrical current that is applied through…”
Get full text

Ceftriaxone treatment after traumatic brain injury restores expression of the glutamate transporter, GLT-1, reduces regional gliosis, and reduces post-traumatic seizures in the rat by Goodrich, Grant S, Kabakov, Anatoli Y, Hameed, Mustafa Q, Dhamne, Sameer C, Rosenberg, Paul A, Rotenberg, Alexander

“…Excessive extracellular glutamate after traumatic brain injury (TBI) contributes to excitotoxic cell death and likely to post-traumatic epilepsy. Glutamate…”
Get more information

Metabolic regulation of endothelial SK channels and human coronary microvascular function by Liu, Yuhong, Kabakov, Anatoli Y., Xie, An, Shi, Guangbin, Singh, Arun K., Sodha, Neel R., Ehsan, Afshin, Usheva, Anny, Agbortoko, Vahid, Koren, Gideon, Dudley, Samuel C., Sellke, Frank W., Feng, Jun

“…Diabetic (DM) inactivation of small conductance calcium-activated potassium (SK) channels contributes to coronary endothelial dysfunction. However, the…”
Get full text

Corrigendum: Three-week-old rabbit ventricular cardiomyocytes as a novel system to study cardiac excitation and EC coupling by Kabakov, Anatoli Y, Sengun, Elif, Lu, Yichun, Roder, Karim, Bronk, Peter, Baggett, Brett, Turan, Nilüfer N, Moshal, Karni S, Koren, Gideon

“…[This corrects the article DOI: 10.3389/fphys.2021.672360.]…”
Get full text

Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling by Kabakov, Anatoli Y, Sengun, Elif, Lu, Yichun, Roder, Karim, Bronk, Peter, Baggett, Brett, Turan, Nilüfer N, Moshal, Karni S, Koren, Gideon

“…Cardiac arrhythmias significantly contribute to cardiovascular morbidity and mortality. The rabbit heart serves as an accepted model system for studying…”
Get full text

Catalytically Dead αCaMKII K42M Mutant Acts as a Dominant Negative in the Control of Synaptic Strength by Kabakov, Anatoli Y, Lisman, John E

“…During long-term potentiation (LTP) of excitatory synapses, Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is activated by Ca(2+) influx through NMDA…”
Get full text

Myofibroblast senescence promotes arrhythmogenic remodeling in the aged infarcted rabbit heart by Baggett, Brett C, Murphy, Kevin R, Sengun, Elif, Mi, Eric, Cao, Yueming, Turan, Nilufer N, Lu, Yichun, Schofield, Lorraine, Kim, Tae Yun, Kabakov, Anatoli Y, Bronk, Peter, Qu, Zhilin, Camelliti, Patrizia, Dubielecka, Patrycja, Terentyev, Dmitry, Del Monte, Federica, Choi, Bum-Rak, Sedivy, John, Koren, Gideon

“…Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known…”
Get full text

GLT-1 Transport Stoichiometry Is Constant at Low and High Glutamate Concentrations when Chloride Is Substituted by Gluconate by Kabakov, Anatoli Y, Rosenberg, Paul A

“…Glutamate is the major excitatory neurotransmitter, but prolonged exposure even at micromolar concentrations causes neuronal death. Extracellular glutamate is…”
Get full text

E3 ubiquitin ligase rififylin has yin and yang effects on rabbit cardiac transient outward potassium currents (Ito) and corresponding channel proteins by Kabakov, Anatoli Y., Roder, Karim, Bronk, Peter, Turan, Nilüfer N., Dhakal, Saroj, Zhong, Mingwang, Lu, Yichun, Zeltzer, Zachary A., Najman-Licht, Yonatan B., Karma, Alain, Koren, Gideon

“…Genome-wide association studies have reported a correlation between a SNP of the RING finger E3 ubiquitin protein ligase rififylin (RFFL) and QT interval…”
Get full text

Coronary endothelial dysfunction prevented by small-conductance calcium-activated potassium channel activator in mice and patients with diabetes by Zhang, Zhiqi, Shi, Guangbin, Liu, Yuhong, Xing, Hang, Kabakov, Anatoli Y., Zhao, Amy S., Agbortoko, Vahid, Kim, Justin, Singh, Arun K., Koren, Gideon, Harrington, Elizabeth O., Sellke, Frank W., Feng, Jun

“…To investigate coronary endothelial protection of a small-conductance calcium-activated potassium (SK) channel activator against a period of…”
Get full text

The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2 by Turan, Nilüfer N., Moshal, Karni S., Roder, Karim, Baggett, Brett C., Kabakov, Anatoli Y., Dhakal, Saroj, Teramoto, Ryota, Chiang, David Yi-Eng, Zhong, Mingwang, Xie, An, Lu, Yichun, Dudley, Samuel C., MacRae, Calum A., Karma, Alain, Koren, Gideon

“…The QT interval is a recording of cardiac electrical activity. Previous genome-wide association studies identified genetic variants that modify the QT interval…”
Get full text

Transient Outward K+ Current (Ito) Underlies the Right Ventricular Initiation of Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long-QT Syndrome Type 1 by Choi, Bum-Rak, Li, Weiyan, Terentyev, Dmitry, Kabakov, Anatoli Y, Zhong, Mingwang, Rees, Colin M, Terentyeva, Radmila, Kim, Tae Yun, Qu, Zhilin, Peng, Xuwen, Karma, Alain, Koren, Gideon

“…BACKGROUND:Sudden death in long-QT syndrome type 1 (LQT1), an inherited disease caused by loss-of-function mutations in KCNQ1, is triggered by early…”
Get full text

Late INa Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2 by Hwang, Jungmin, Kim, Tae Yun, Terentyev, Dmitry, Zhong, Mingwang, Kabakov, Anatoli Y., Bronk, Peter, Arunachalam, Karuppiah, Belardinelli, Luiz, Rajamani, Sridharan, Kunitomo, Yukiko, Pfeiffer, Zachary, Lu, Yichun, Peng, Xuwen, Odening, Katja E., Qu, Zhilin, Karma, Alain, Koren, Gideon, Choi, Bum-Rak

“…BACKGROUNDLong QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular…”
Get full text

Late I Na Blocker GS967 Supresses Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long QT Type 2 by Hwang, Jungmin, Kim, Tae Yun, Terentyev, Dmitry, Zhong, Mingwang, Kabakov, Anatoli Y, Bronk, Peter, Arunachalam, Karuppiah, Belardinelli, Luiz, Rajamani, Sridharan, Kunitomo, Yukiko, Pfeiffer, Zachary, Lu, Yichun, Peng, Xuwen, Odening, Katja E, Qu, Zhilin, Karma, Alain, Koren, Gideon, Choi, Bum-Rak

“…Long QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular tachycardias…”
Get full text

Regulation of Glutamate Transport in Developing Rat Oligodendrocytes by DeSilva, Tara M, Kabakov, Anatoli Y, Goldhoff, Patricia E, Volpe, Joseph J, Rosenberg, Paul A

“…Glutamate released from synaptic vesicles mediates excitatory neurotransmission by stimulating glutamate receptors. Glutamate transporters maintain low…”
Get full text

LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor) Regulates Cardiac L-Type Calcium Channels by Modulating NEDD (Neural Precursor Cell Expressed Developmentally Downregulated Protein) 4-1 Ubiquitin Ligase by Moshal, Karni S, Roder, Karim, Kabakov, Anatoli Y, Werdich, Andreas A, Chiang, David Yi-Eng, Turan, Nilüfer N, Xie, An, Kim, Tae Yun, Cooper, Leroy L, Lu, Yichun, Zhong, Mingwang, Li, Weiyan, Terentyev, Dmitry, Choi, Bum-Rak, Karma, Alain, MacRae, Calum A, Koren, Gideon

“…The turnover of cardiac ion channels underlying action potential duration is regulated by ubiquitination. Genome-wide association studies of QT interval…”
Get full text

Evidence for change in current-flux coupling of GLT1 at high glutamate concentrations in rat primary forebrain neurons and GLT1a-expressing COS-7 cells by Kabakov, Anatoli Y., Rosenberg, Paul A.

“…Glutamate is the major excitatory neurotransmitter of the central nervous system and is toxic to neurons even at low concentrations. GLT1, the rodent analog of…”
Get full text

Catalytically Dead [alpha]CaMKII K42M Mutant Acts as a Dominant Negative in the Control of Synaptic Strength by Kabakov, Anatoli Y, Lisman, John E

“…During long-term potentiation (LTP) of excitatory synapses, Ca.sup.2+ /calmodulin-dependent protein kinase II (CaMKII) is activated by Ca.sup.2+ influx through…”
Get full text

Ubiquitin Ligase Rififylin (RFFL) Has Yin-Yang Effects on Rabbit Cardiac Transient Outward (Ito) Potassium Channels by Kabakov, Anatoli Y., Roder, Karim, Moshal, Karni S., Lu, YiChun, Zhong, Mingwang, Dhakal, Saroj, Karma, Alain, Koren, Gideon

Get full text

3-Week-Old Rabbit Cardiomyocytes (3wRbCM): A Novel Cellular Model for Studying Cardiac Excitation by Kabakov, Anatoli Y., Moshal, Karni, Lu, YiChun, Roder, Karim, Nilufer, Turan, Li, Weiyan, Murphy, Kevin, Terentyev, Dmitry, Koren, Gideon

Get full text