Search Results - "Kaatsch, Leonhard"
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X-ray irradiation induces subtle changes in the genome-wide distribution of DNA hydroxymethylation with opposing trends in genic and intergenic regions
Published in Epigenetics (02-01-2019)“…DNA hydroxymethylation has gained attention as an intermediate in the process of DNA demethylation. More recently, 5-hydroxymethylcytosine has been recognized…”
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Gene expression changes and DNA damage after ex vivo exposure of peripheral blood cells to various CT photon spectra
Published in Scientific reports (08-06-2021)“…Dual-energy CT provides enhanced diagnostic power with similar or even reduced radiation dose as compared to single-energy CT. Its principle is based on the…”
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Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation
Published in International journal of molecular sciences (24-01-2021)“…Sulfur mustard (SM) is a chemical warfare agent that can damage DNA via alkylation and oxidative stress. Because of its genotoxicity, SM is cancerogenic and…”
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Improved Discriminability of Severe Lung Injury and Atelectasis in Thoracic Trauma at Low keV Virtual Monoenergetic Images from Photon-Counting Detector CT
Published in Diagnostics (Basel) (06-10-2024)“…: To evaluate the value of virtual monoenergetic images (VMI) from photon-counting detector CT (PCD-CT) for discriminability of severe lung injury and…”
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Radiation exposure during angiographic interventions in interventional radiology - risk and fate of advanced procedures
Published in International journal of radiation biology (04-05-2022)“…Advanced angiographic procedures in interventional radiology are becoming more important and are more frequently used, especially in the treatment of several…”
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Initial experience on abdominal photon-counting computed tomography in clinical routine: general image quality and dose exposure
Published in European radiology (01-04-2023)“…Objectives Photon-counting computed tomography has lately found its way into clinical routine. The new technique could offer substantial improvements regarding…”
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Abemaciclib and Letrozole in Metastatic Male Breast Cancer
Published in Cancer reports (01-11-2024)“…ABSTRACT Background Male breast cancer is a very rare disease and only accounts for around 1% of all breast cancers. The treatment strategies are based on…”
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Impact of medical imaging on the epigenome - low-dose exposure in the course of computed tomography does not induce detectable changes of DNA-methylation profiles in peripheral blood cells
Published in International journal of radiation biology (04-05-2022)“…Computed tomography (CT) is a main contributor to artificial low-dose exposure. Understanding the biological effects induced by CT exposure and their…”
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Ultra-low-dose photon-counting CT of paranasal sinus: an in vivo comparison of radiation dose and image quality to cone-beam CT
Published in Dento-maxillo-facial radiology (08-02-2024)“…This study investigated the differences in subjective and objective image parameters as well as dose exposure of photon-counting CT (PCCT) compared to…”
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CT Irradiation-induced Changes of Gene Expression within Peripheral Blood Cells
Published in Health physics (1958) (01-07-2020)“…ABSTRACTComputed tomography (CT) is a crucial element of medical imaging diagnostics. The widespread application of this technology has made CT one of the…”
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