Search Results - "Kaartinen, T."

Transglutaminase activity regulates differentiation, migration and fusion of osteoclasts via affecting actin dynamics by Sun, Huifang, Kaartinen, Mari T.

“…Osteoclasts, bone resorbing cells, derive from monocyte/macrophage cell lineage. Increased osteoclast activity is responsible for bone destruction in diseases…”
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Transglutaminase regulation of cell function by Eckert, Richard L, Kaartinen, Mari T, Nurminskaya, Maria, Belkin, Alexey M, Colak, Gozde, Johnson, Gail V W, Mehta, Kapil

“…Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding functions that participate in regulation of cell fate in a wide range of…”
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Transglutaminase 1: Emerging Functions beyond Skin by Ebrahimi Samani, Sahar, Tatsukawa, Hideki, Hitomi, Kiyotaka, Kaartinen, Mari T

“…Transglutaminase enzymes catalyze Ca - and thiol-dependent posttranslational modifications of glutamine-residues that include esterification, hydrolysis and…”
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Transglutaminases and Obesity in Humans: Association of F13A1 to Adipocyte Hypertrophy and Adipose Tissue Immune Response by Kaartinen, Mari T, Arora, Mansi, Heinonen, Sini, Rissanen, Aila, Kaprio, Jaakko, Pietiläinen, Kirsi H

“…Transglutaminases TG2 and FXIII-A have recently been linked to adipose tissue biology and obesity, however, human studies for TG family members in adipocytes…”
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Factor XIII-A transglutaminase acts as a switch between preadipocyte proliferation and differentiation by Myneni, Vamsee D., Hitomi, Kiyotaka, Kaartinen, Mari T.

“…Factor XIII-A (FXIII-A) transglutaminase (TG) was recently identified as a potential causative obesity gene in human white adipose tissue (WAT). Here, we have…”
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Increased Osteoclastogenesis in Absence of TG2 Is Reversed by Transglutaminase Inhibition-Evidence for the Role for TG1 in Osteoclast Formation by Ebrahimi Samani, Sahar, Kaartinen, Mari T

“…Osteoclasts are multinucleated, bone-resorbing giant cells derived from monocyte-macrophage cell lines. Increased bone resorption results in loss of bone mass…”
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Mineralization-inhibiting effects of transglutaminase-crosslinked polymeric osteopontin by Hoac, Betty, Nelea, Valentin, Jiang, Wenge, Kaartinen, Mari T, McKee, Marc D

“…Abstract Osteopontin (OPN) belongs to the SIBLING family (Small, Integrin-Binding LIgand N-linked Glycoproteins) of mineral-binding matrix proteins found in…”
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Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow by Mousa, Aisha, Cui, Cui, Song, Aimei, Myneni, Vamsee D, Sun, Huifang, Li, Jin Jin, Murshed, Monzur, Melino, Gerry, Kaartinen, Mari T

“…Appropriate bone mass is maintained by bone-forming osteoblast and bone-resorbing osteoclasts. Mesenchymal stem cell (MSC) lineage cells control…”
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Pyrophosphate Inhibits Mineralization of Osteoblast Cultures by Binding to Mineral, Up-regulating Osteopontin, and Inhibiting Alkaline Phosphatase Activity by Addison, William N., Azari, Fereshteh, Sørensen, Esben S., Kaartinen, Mari T., McKee, Marc D.

“…Inorganic pyrophosphate (PPi) produced by cells inhibits mineralization by binding to crystals. Its ubiquitous presence is thought to prevent “soft” tissues…”
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Liberation of Printed Circuit Assembly (PCA) and dust generation in relation to mobile phone design in a size reduction process by Bachér, J., Kaartinen, T.

“…•We compare mobile phone design on the Printed Circuit Assembly (PCA) liberation.•We identify dust generation and composition in relation to mobile phone…”
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Peptidic Inhibitors and a Fluorescent Probe for the Selective Inhibition and Labelling of Factor XIIIa Transglutaminase by Gates, Eric W J, Mansour, Kian, Ebrahimi Samani, Sahar, Shad, Sammir, Kaartinen, Mari T, Keillor, Jeffrey W

“…Factor XIIIa (FXIIIa) is a transglutaminase of major therapeutic interest for the development of anticoagulants due to its essential role in the blood…”
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F13A1 transglutaminase expression in human adipose tissue increases in acquired excess weight and associates with inflammatory status of adipocytes by Kaartinen, M. T., Arora, M., Heinonen, S., Hang, A., Barry, A., Lundbom, J., Hakkarainen, A., Lundholm, N., Rissanen, A., Kaprio, J., Pietiläinen, K. H.

“…Objective F13A1 /FXIII-A transglutaminase has been linked to adipogenesis in cells and to obesity in humans and mice, however, its role and associated…”
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Transglutaminases in Monocytes and Macrophages by Sun, Huifang, Kaartinen, Mari T

“…Macrophages are key players in various inflammatory disorders and pathological conditions via phagocytosis and orchestrating immune responses. They are highly…”
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Factor XIII-A transglutaminase deficient mice show signs of metabolically healthy obesity on high fat diet by Myneni, Vamsee D., Mousa, Aisha, Kaartinen, Mari T.

“…F13A1 gene, which encodes for Factor XIII-A blood clotting factor and a transglutaminase enzyme, was recently identified as a potential causative gene for…”
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Osteopontin and wound healing in bone by McKee, Marc D, Pedraza, Claudio E, Kaartinen, Mari T

“…Bone wound healing after surgical drilling/cutting initially involves a typical inflammatory response with a leukocyte-rich cell infiltrate whose professional…”
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ATP-mediated mineralization of MC3T3-E1 osteoblast cultures by Nakano, Yukiko, Addison, William N, Kaartinen, Mari T

“…Abstract While bone is hypomineralized in hypophosphatemia patients and in tissue-nonspecific alkaline phosphatase (Tnsalp)-deficient mice, the extensive…”
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Cellular Factor XIIIA Transglutaminase Localizes in Caveolae and Regulates Caveolin-1 Phosphorylation, Homo-oligomerization and c-Src Signaling in Osteoblasts by Wang, Shuai, Kaartinen, Mari T.

“…Transglutaminases (TGs) are a family of widely distributed enzymes that catalyze protein crosslinking by forming a covalent isopeptide bond between the…”
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Collagens Regulating Adipose Tissue Formation and Functions by Jääskeläinen, Iida, Petäistö, Tiina, Mirzarazi Dahagi, Elahe, Mahmoodi, Mahdokht, Pihlajaniemi, Taina, Kaartinen, Mari T, Heljasvaara, Ritva

“…The globally increasing prevalence of obesity is associated with the development of metabolic diseases such as type 2 diabetes, dyslipidemia, and fatty liver…”
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Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics by Al-Jallad, Hadil F, Myneni, Vamsee D, Piercy-Kotb, Sarah A, Chabot, Nicolas, Mulani, Amina, Keillor, Jeffrey W, Kaartinen, Mari T

“…Transglutaminase activity, arising potentially from transglutaminase 2 (TG2) and Factor XIIIA (FXIIIA), has been linked to osteoblast differentiation where it…”
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Circulating plasma fibronectin affects tissue insulin sensitivity, adipocyte differentiation, and transcriptional landscape of adipose tissue in mice by Mahmoodi, Mahdokht, Mirzarazi Dahagi, Elahe, Nabavi, Mir‐Hamed, Penalva, Ylauna C. M., Gosaine, Amrita, Murshed, Monzur, Couldwell, Sandrine, Munter, Lisa M., Kaartinen, Mari T.

“…Plasma fibronectin (pFN) is a hepatocyte‐derived circulating extracellular matrix protein that affects cell morphology, adipogenesis, and insulin signaling of…”
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