Search Results - "KYUNG SOOK CHUNG"

Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids by Mun, Seon Ju, Ryu, Jae-Sung, Lee, Mi-Ok, Son, Ye Seul, Oh, Soo Jin, Cho, Hyun-Soo, Son, Mi-Young, Kim, Dae-Soo, Kim, Su Jung, Yoo, Hyun Ju, Lee, Ho-Joon, Kim, Janghwan, Jung, Cho-Rok, Chung, Kyung-Sook, Son, Myung Jin

“…[Display omitted] •Pluripotent stem cell (PSC)-derived expandable human hepatocyte-like liver organoids were generated.•PSC-derived human hepatic organoids are…”
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Genetic interactions reveal the antagonistic roles of FT/TSF and TFL1 in the determination of inflorescence meristem identity in Arabidopsis by Lee, Chunghee, Kim, Soo‐Jin, Jin, Suhyun, Susila, Hendry, Youn, Geummin, Nasim, Zeeshan, Alavilli, Hemasundar, Chung, Kyung‐Sook, Yoo, Seong Jeon, Ahn, Ji Hoon

“…Summary During the transition to the reproductive phase, the shoot apical meristem switches from the developmental program that generates vegetative organs to…”
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Rosmarinic acid represses colitis-associated colon cancer: A pivotal involvement of the TLR4-mediated NF-κB-STAT3 axis by Jin, Bo-Ram, Chung, Kyung-Sook, Hwang, Soonjae, Hwang, Sam Noh, Rhee, Ki-Jong, Lee, Minho, An, Hyo-Jin

“…Previously, we found that rosmarinic acid (RA) exerted anti-inflammatory activities in a dextran sulfate sodium (DSS)-induced colitis model. Here, we…”
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In vitro modeling of liver fibrosis with 3D co‐culture system using a novel human hepatic stellate cell line by Lee, Ho‐Joon, Mun, Seon Ju, Jung, Cho‐Rok, Kang, Hyun‐Mi, Kwon, Jae‐Eun, Ryu, Jae‐Sung, Ahn, Hyo‐Suk, Kwon, Ok‐Seon, Ahn, Jiwon, Moon, Kyung‐Sik, Son, Myung Jin, Chung, Kyung‐Sook

“…Hepatic stellate cells (HSCs) play an important role in liver fibrosis; however, owing to the heterogeneity and limited supply of primary HSCs, the development…”
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The Inhibitory Effect of Nodakenin on Mast‐Cell‐Mediated Allergic Inflammation Via Downregulation of NF‐κB and Caspase‐1 Activation by Lee, Na Young, Chung, Kyung‐Sook, Jin, Jong Sik, Lee, Young‐Cheol, An, Hyo‐Jin

“…ABSTRACT Nodakenin, a coumarin isolated from the roots of Angelicae gigas, is effective for treating function control disorders, bacterial infections, pain,…”
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A liver‐specific gene expression panel predicts the differentiation status of in vitro hepatocyte models by Kim, Dae‐Soo, Ryu, Jea‐Woon, Son, Mi‐Young, Oh, Jung‐Hwa, Chung, Kyung‐Sook, Lee, Sugi, Lee, Jeong‐Ju, Ahn, Jun‐Ho, Min, Ju‐Sik, Ahn, Jiwon, Kang, Hyun Mi, Kim, Janghwan, Jung, Cho‐Rok, Kim, Nam‐Soon, Cho, Hyun‐Soo

“…Alternative cell sources, such as three‐dimensional organoids and induced pluripotent stem cell–derived cells, might provide a potentially effective approach…”
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Optimization of 3D hydrogel microenvironment for enhanced hepatic functionality of primary human hepatocytes by Lee, Ho‐Joon, Ahn, Jiwon, Jung, Cho‐Rock, Jeung, Yun‐Ji, Cho, Hyun‐Soo, Son, Myung Jin, Chung, Kyung‐Sook

“…Although primary human hepatocytes (PHHs) are the gold standard in drug efficacy and metabolism studies, long‐term survival of PHHs and maintenance of their…”
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Efficient and reproducible generation of human induced pluripotent stem cell-derived expandable liver organoids for disease modeling by Mun, Seon Ju, Hong, Yeon-Hwa, Shin, Yongbo, Lee, Jaeseo, Cho, Hyun-Soo, Kim, Dae-Soo, Chung, Kyung-Sook, Son, Myung Jin

“…Genetic liver disease modeling is difficult because it is challenging to access patient tissue samples and to develop practical and relevant model systems…”
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β-Caryophyllene in the Essential Oil from Chrysanthemum Boreale Induces G1 Phase Cell Cycle Arrest in Human Lung Cancer Cells by Chung, Kyung-Sook, Hong, Joo Young, Lee, Jeong-Hun, Lee, Hae-Jun, Park, Ji Yeon, Choi, Jung-Hye, Park, Hee-Juhn, Hong, Jongki, Lee, Kyung-Tae

“…Chrysanthemum boreale is a plant widespread in East Asia, used in folk medicine to treat various disorders, such as pneumonia, colitis, stomatitis, and…”
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Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase by Hassan, Ahmed H. E., Oh, Yeon Il, Lee, Chae Hyeon, Kim, Yeon Ju, Cho, Soo Bin, Alam, Md. Maqusood, Park, Sang-Eun, Chung, Kyung-Sook, Lee, Kyung-Tae, Lee, Yong Sup

“…Phenethyl-based edelfosine-analogs with saturated, monounsaturated, or polyunsaturated alkoxy substituents on phenyl ring were designed as novel antitumor…”
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Anti-Inflammatory Mechanisms of Koreanaside A, a Lignan Isolated from the Flower of Forsythia koreana , against LPS-Induced Macrophage Activation and DSS-Induced Colitis Mice: The Crucial Role of AP-1, NF-κB, and JAK/STAT Signaling by Kim, Tae-Woo, Shin, Ji-Sun, Chung, Kyung-Sook, Lee, Yeong-Geun, Baek, Nam-In, Lee, Kyung-Tae

“…The current treatment options for inflammatory bowel disease (IBD) are unsatisfactory. Therefore, novel and safer therapies are needed. We previously reported…”
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Establishment of a human induced pluripotent stem cell line, KRIBBi006-A, from peripheral blood mononuclear cells derived from a healthy male donor by Kwon, Ok-Seon, Na, Hyeon-Jin, Ahn, Jiwon, Chung, Kyung-Sook

“…Given the advantage of being able to be extracted by a minimally invasive method, blood is regarded as a suitable cell source for reprogramming to establish…”
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Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel Particulate Matter by Jung, Seang-Hwan, Chung, Kyung-Sook, Ahn, Hye-Shin, Shin, Yu-Kyong, Lee, Kyung-Tae

“…Air pollution causes various airway diseases. However, many commonly used treatments can have high risks of side effects or are costly. To examine the…”
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Developing scalable cultivation systems of hepatic spheroids for drug metabolism via genomic and functional analyses by Ahn, Jiwon, Lee, Ho‐Joon, Oh, Soo Jin, Kim, Wantae, Mun, Seon Ju, Lee, Jae‐Hye, Jung, Cho‐Rock, Cho, Hyun‐Soo, Kim, Dae‐Soo, Son, Myung Jin, Chung, Kyung‐Sook

“…Spheroids, a widely used three‐dimensional (3D) culture model, are standard in hepatocyte culture as they preserve long‐term hepatocyte functionality and…”
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Dieckol Isolated from Eisenia bicyclis Ameliorates Wrinkling and Improves Skin Hydration via MAPK/AP-1 and TGF-β/Smad Signaling Pathways in UVB-Irradiated Hairless Mice by Kim, Jae-Min, Chung, Kyung-Sook, Yoon, Young-Seo, Jang, Seo-Yun, Heo, So-Won, Park, Geonha, Jang, Young-Pyo, Ahn, Hye-Shin, Shin, Yu-Kyong, Lee, Sun-Hee, Lee, Kyung-Tae

“…Repetitive exposure to ultraviolet B (UVB) is one of the main causes of skin photoaging. We previously reported that dieckol isolated from extract has…”
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Standardized Ethanol Extract of Cassia mimosoides var. nomame Makino Ameliorates Obesity via Regulation of Adipogenesis and Lipogenesis in 3T3-L1 Cells and High-Fat Diet-Induced Obese Mice by Heo, So-Won, Chung, Kyung-Sook, Yoon, Young-Seo, Kim, Soo-Yeon, Ahn, Hye-Shin, Shin, Yu-Kyong, Lee, Sun-Hee, Lee, Kyung-Tae

“…Obesity is a major cause of conditions such as type 2 diabetes and non-alcoholic fatty liver disease, posing a threat to public health worldwide. Here, we…”
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Cationic amino acid transporter PQLC2 is a potential therapeutic target in gastric cancer by Jeung, Yun‐Ji, Lee, Kyeong, Lee, Hyo Jin, Kim, Eunah, Son, Myung Jin, Ahn, Jiwon, Kim, Han‐Gyeul, Kim, Wantae, Lee, Ho‐Joon, Kim, Jin Man, Chung, Kyung‐Sook

“…Tumor cells overexpress amino acid transporters to meet the increased demand for amino acids. PQ loop repeat‐containing (PQLC)2 is a cationic amino acid…”
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High-Fat Diet Propelled AOM/DSS-Induced Colitis-Associated Colon Cancer Alleviated by Administration of Aster glehni via STAT3 Signaling Pathway by Jin, Bo-Ram, Chung, Kyung-Sook, Lee, Minho, An, Hyo-Jin

“…Many epidemiological observational studies suggest that a high-fat diet (HFD) accelerates the risk of colorectal cancer (CRC). Inflammation can play a key role…”
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Improved tumor-suppressive effect of OZ-001 combined with cisplatin mediated by mTOR/p70S6K and STAT3 inactivation in A549 human lung cancer cells by Lee, Jeong-Hun, Chung, Kyung-Sook, Lee, Hwi-Ho, Ko, Dohyeong, Kang, Minji, Yoo, Ho, Ahn, JooHoon, Lee, Jae Yeol, Lee, Kyung-Tae

“…We previously reported the anticancer activity of…”
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Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice by Chung, Kyung-Sook, Cheon, Se-Yun, Roh, Seong-Soo, Lee, Minho, An, Hyo-Jin

“…Although is a common dietary herb that has various bioactivities, including anti-diabetic, anti-adipogenic, and anti-inflammatory effects, has not been studied…”
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