Search Results - "KYU PIL LEE"

Progesterone increases blood glucose via hepatic progesterone receptor membrane component 1 under limited or impaired action of insulin by Lee, Sang R., Choi, Woo-Young, Heo, Jun H., Huh, Jiyoung, Kim, Globinna, Lee, Kyu-Pil, Kwun, Hyo-Jung, Shin, Hyun-Jin, Baek, In-Jeoung, Hong, Eui-Ju

“…Hepatic gluconeogenesis is the main pathway for blood glucose maintenance activated during fasting. Retardation of insulin action, such as in diabetes…”
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Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration by Lee, Sang R., Heo, Jun H., Jo, Seong Lae, Kim, Globinna, Kim, Su Jung, Yoo, Hyun Ju, Lee, Kyu-Pil, Kwun, Hyo-Jung, Shin, Hyun-Jin, Baek, In-Jeoung, Hong, Eui-Ju

“…Obesity is implicated in cardiovascular disease and heart failure. When fatty acids are transported to and not adequately oxidized in cardiac cells, they…”
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Evaluation of nafamostat mesilate as an alternative anticoagulant during intermittent hemodialysis in healthy Beagle dogs by Choi, Joon‐hyuk, Byun, Seok‐yeong, Nam, Aryung, Han, Sei‐myoung, Lee, Kyu‐pil, Song, Kun‐ho, Youn, Hwa‐young, Seo, Kyoung‐won

“…Objective To evaluate nafamostat mesilate (NM) as an alternative anticoagulant agent for intermittent hemodialysis (IHD). Design Prospective randomized study…”
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Functional identification of protein phosphatase 1-binding consensus residues in NBCe1-B by Lee, Kyu Pil, Kim, Hyun Jin, Yang, Dongki

“…Protein phosphatase 1 (PP1) is involved in various signal transduction mechanisms as an extensive regulator. The PP1 catalytic subunit (PP1c) recognizes and…”
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Perspectives on Potential Fatty Acid Modulations of Motility Associated Human Sperm Ion Channels by Cooray, Akila, Kim, Ji Hyun, Chae, Mee Ree, Lee, Sungwon, Lee, Kyu Pil

“…Human spermatozoan ion channels are specifically distributed in the spermatozoan membrane, contribute to sperm motility, and are associated with male…”
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Hydrophobic interactions within the C terminus pole helices tunnel regulate calcium-dependent inactivation of TRPC3 in a calmodulin-dependent manner by Wijerathne, Tharaka, Lin, Wei-Yin, Cooray, Akila, Muallem, Shmuel, Lee, Kyu Pil

“…•Hydrophobic interaction in the pole helix in TRPC3 is important for TRPC channel function.•Mutation interrupting pole helix hydrophobic interaction attenuates…”
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Pharmacological Evidence Suggests That Slo3 Channel Is the Principal K + Channel in Boar Spermatozoa by Cooray, Akila, Kim, Jeongsook, Nirujan, Beno Ramesh, Jayathilake, Nishani Jayanika, Lee, Kyu Pil

“…Sperm ion channels are associated with the quality and type of flagellar movement, and their differential regulation is crucial for sperm function during…”
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The aqueous fraction of Castanea crenata inner shell extract reduces obesity and intramuscular lipid accumulation via induction of mitochondrial respiration and fatty acid oxidation in muscle by Lee, Sang R., Jo, Seong Lae, Heo, Jun H., Kim, Tae-Won, Lee, Kyu-Pil, Hong, Eui-Ju

“…Skeletal muscle is responsible for free fatty acid (FFA) disposal via mitochondrial respiration and fatty acid oxidation (FAO). Obesity triggers high levels of…”
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Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease by Hong, Chansik, Seo, Hyemyung, Kwak, Misun, Jeon, Jeha, Jang, Jihoon, Jeong, Eui Man, Myeong, Jongyun, Hwang, Yu Jin, Ha, Kotdaji, Kang, Min Jueng, Lee, Kyu Pil, Yi, Eugene C, Kim, In-Gyu, Jeon, Ju-Hong, Ryu, Hoon, So, Insuk

“…Aberrant glutathione or Ca(2+) homeostasis due to oxidative stress is associated with the pathogenesis of neurodegenerative disorders. The Ca(2+)-permeable…”
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Molecular Determinants Mediating Gating of Transient Receptor Potential Canonical (TRPC) Channels by Stromal Interaction Molecule 1 (STIM1) by Lee, Kyu Pil, Choi, Seok, Hong, Jeong Hee, Ahuja, Malini, Graham, Sarabeth, Ma, Rong, So, Insuk, Shin, Dong Min, Muallem, Shmuel, Yuan, Joseph P.

“…Transient receptor potential canonical (TRPC) channels mediate a critical part of the receptor-evoked Ca2+ influx. TRPCs are gated open by the endoplasmic…”
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An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs by Lee, Kyu Pil, Yuan, Joseph P., Hong, Jeong Hee, So, Insuk, Worley, Paul F., Muallem, Shmuel

“…Ca 2+ entering cells through store-operated channels (SOCs) affects most cell functions, and excess SOC is associated with pathologies. The molecular makeup of…”
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Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BK Ca activator LDD175 by Wijerathne, Tharaka Darshana, Kim, Jihyun, Yang, Dongki, Lee, Kyu Pil

“…Plasma membrane hyperpolarization associated with activation of $Ca^{2+}$-activated $K^+$ channels plays an important role in sperm capacitation during…”
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Molecular determinants of fast Ca²⁺-dependent inactivation and gating of the Orai channels by Lee, Kyu Pil, Yuan, Joseph P, Zeng, Weizhong, So, Insuk, Worley, Paul F, Muallem, Shmuel

“…Ca²⁺ influx by store-operated Ca²⁺ influx channels (SOCs) mediates many cellular functions regulated by Ca²⁺, and excessive SOC-mediated Ca²⁺ influx is…”
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The interaction domains of transient receptor potential canonical (TRPC)1/4 and TRPC1/5 heteromultimeric channels by Myeong, Jongyun, Ko, Juyeon, Hong, Chansik, Yang, Dongki, Lee, Kyu Pil, Jeon, Ju-hong, So, Insuk

“…Transient receptor potential canonical (TRPC) family contains a non-selective cation channel, and four TRPC subunits form a functional tetrameric channel…”
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Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+ -Dependent Toxicity by Kim, Min Seuk, Lee, Kyu Pil, Yang, Dongki, Shin, Dong Min, Abramowitz, Joel, Kiyonaka, Shigeki, Birnbaumer, Lutz, Mori, Yasuo, Muallem, Shmuel

“…Background & Aims Excessive Ca2+ influx mediates many cytotoxic processes, including those associated with autoimmune inflammatory diseases such as acute…”
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Comparison of GaN p-i-n and Schottky rectifier performance by Zhan, A.P., Dang, G.T., Fan Ren, Hyun Cho, Kyu-Pil Lee, Pearton, S.J., Jenn-Inn Chyi, Nee, T.-Y., Chuo, C.-C.

“…The performance of GaN p-i-n and Schottky rectifiers fabricated on the same wafer was investigated as a function of device size and operating temperature…”
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Investigation on urinary and serum alpha klotho in dogs with chronic kidney disease by Yi, Hong Jae, Lee, Jong Bok, Lee, Kyu Pil, Oh, Ye-In, Song, Kun Ho, Seo, Kyoung Won

“…As a co-receptor for fibroblast growth factor 23, klotho plays a pivotal role in phosphate metabolism. The kidney is known to be the main source of soluble…”
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Potential of Bacteriocins from Lactobacillus taiwanensis for Producing Bacterial Ghosts as a Next Generation Vaccine by Kim, Sam Woong, Ha, Yeon Jo, Bang, Kyu Ho, Lee, Seungki, Yeo, Joo-Hong, Yang, Hee-Sun, Kim, Tae-Won, Lee, Kyu Pil, Bang, Woo Young

“…Bacteriocins are functionally diverse toxins produced by most microbes and are potent antimicrobial peptides (AMPs) for bacterial ghosts as next generation…”
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Methionine Sulfoxide Reductase B1 (MsrB1) Recovers TRPM6 Channel Activity during Oxidative Stress by Cao, Gang, Lee, Kyu pil, van der Wijst, Jenny, de Graaf, Mark, van der Kemp, AnneMiete, Bindels, René J.M., Hoenderop, Joost G.J.

“…Mg2+ is an essential ion for many cellular processes, including protein synthesis, nucleic acid stability, and numerous enzymatic reactions. Mg2+ homeostasis…”
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Cryopreservation of Pig Semen Using a Quercetin-Supplemented Freezing Extender by Bang, Seonggyu, Tanga, Bereket Molla, Fang, Xun, Seong, Gyeonghwan, Saadeldin, Islam M, Qamar, Ahmad Yar, Lee, Sanghoon, Kim, Keun-Jung, Park, Yun-Jae, Nabeel, Abdelbagi Hamad Talha, Yu, Il-Jeoung, Cooray, Akila, Lee, Kyu Pil, Cho, Jongki

“…Reactive oxygen species (ROS) produced during freeze−thaw procedures cause oxidative damage to the sperm, reducing fertility. We aimed to improve the post-thaw…”
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