Search Results - "KYOUNG SANG, CHO"
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Neuroprotective Effects of Limonene (+) against Aβ42-Induced Neurotoxicity in a Drosophila Model of Alzheimer’s Disease
Published in Biological & pharmaceutical bulletin (01-03-2020)“…Forest bathing is suggested to have beneficial effects on various aspects of human health. Terpenes, isoprene based-phytochemicals emitted from trees, are…”
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2
Nardostachys jatamansi Ethanol Extract Ameliorates Aβ42 Cytotoxicity
Published in Biological & pharmaceutical bulletin (2018)“…The Nardostachys jatamansi DC (NJ) root has been used as a sedative or analgesic to treat neurological symptoms and pain in traditional Korean medicine. Here,…”
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In Vivo Screening of Traditional Medicinal Plants for Neuroprotective Activity against Aβ42 Cytotoxicity by Using Drosophila Models of Alzheimer’s Disease
Published in Biological & pharmaceutical bulletin (2015)“…Alzheimer’s disease (AD) is the most common neurodegenerative disorder, characterized by progressive neuronal loss with amyloid β-peptide (Aβ) plaques. Despite…”
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4
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production
Published in The FASEB journal (01-09-2001)“…The Akt/protein kinase B (PKB) serine/ threonine kinase is well known as an important mediator of many cell survival signaling pathways. Here, we demonstrate…”
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Therapeutic Potential of Volatile Terpenes and Terpenoids from Forests for Inflammatory Diseases
Published in International journal of molecular sciences (22-03-2020)“…Forest trees are a major source of biogenic volatile organic compounds (BVOCs). Terpenes and terpenoids are known as the main BVOCs of forest aerosols. These…”
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6
Functional Characterization of Drosophila melanogaster CYP6A8 Fatty Acid Hydroxylase
Published in Biomolecules & therapeutics (01-01-2023)“…Genomic analysis indicated that the genome of Drosophila melanogaster contains more than 80 cytochrome P450 genes. To date, the enzymatic activity of these…”
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Suppressive Effects of SuHeXiang Wan on Amyloid-β42-Induced Extracellular Signal-Regulated Kinase Hyperactivation and Glial Cell Proliferation in a Transgenic Drosophila Model of Alzheimer's Disease
Published in Biological & pharmaceutical bulletin (2013)“…SuHeXiang Wan (SHXW), a Chinese traditional medicine, has been used to treat infantile convulsions, seizures and strokes. Previously, we reported that modified…”
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Recent Advances in Studies on the Therapeutic Potential of Dietary Carotenoids in Neurodegenerative Diseases
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Carotenoids, symmetrical tetraterpenes with a linear C40 hydrocarbon backbone, are natural pigment molecules produced by plants, algae, and fungi. Carotenoids…”
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Conformational change of organic cofactor PLP is essential for catalysis in PLP-dependent enzymes
Published in BMB reports (30-09-2022)“…Pyridoxal 5’-phosphate (PLP)-dependent enzymes are ubiquitous, catalyzing various biochemical reactions of approximately 4% of all classified enzymatic…”
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10
Physical Exercise-Induced Myokines in Neurodegenerative Diseases
Published in International journal of molecular sciences (28-05-2021)“…Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis…”
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Evaluation of Traditional Medicines for Neurodegenerative Diseases Using Drosophila Models
Published in Evidence-based complementary and alternative medicine (01-01-2014)“…Drosophila is one of the oldest and most powerful genetic models and has led to novel insights into a variety of biological processes. Recently, Drosophila has…”
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12
Autophagy Modulators and Neuroinflammation
Published in Current medicinal chemistry (01-01-2020)“…Neuroinflammation plays a critical role in the development and progression of various neurological disorders. Therefore, various studies have focused on the…”
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13
Neurodevelopmental disorders with epigenetic dysregulation and Drosophila
Published in Frontiers in bioscience (Landmark. Print) (01-06-2019)“…Recently, the mechanisms underlying epigenetic dysregulation associated with neurodevelopmental disorders have attracted increasing attention. Although most…”
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14
Terpenes from Forests and Human Health
Published in Toxicological research (Seoul) (01-04-2017)“…Forest bathing has beneficial effects on human health via showering of forest aerosols as well as physical relaxation. Terpenes that consist of multiple…”
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15
Genetic Dissection of Alzheimer's Disease Using Drosophila Models
Published in International journal of molecular sciences (30-01-2020)“…Alzheimer's disease (AD), a main cause of dementia, is the most common neurodegenerative disease that is related to abnormal accumulation of the amyloid β (Aβ)…”
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16
Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation
Published in International journal of molecular sciences (15-07-2021)“…Primary cilia are nonmotile cellular signal-sensing antenna-like structures composed of microtubule-based structures that distinguish them from motile cilia in…”
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17
Histone Lysine Methylation and Neurodevelopmental Disorders
Published in International journal of molecular sciences (30-06-2017)“…Methylation of several lysine residues of histones is a crucial mechanism for relatively long-term regulation of genomic activity. Recent molecular biological…”
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Roles of ZnT86D in Neurodevelopment and Pathogenesis of Alzheimer Disease in a Drosophila melanogaster Model
Published in International journal of molecular sciences (01-10-2022)“…Zinc is a fundamental trace element essential for numerous biological processes, and zinc homeostasis is regulated by the Zrt-/Irt-like protein (ZIP) and zinc…”
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Overexpression of H3K36 methyltransferase NSD in glial cells affects brain development in Drosophila
Published in Glia (01-12-2020)“…NSD1 is a histone methyltransferase that methylates the lysine 36 at histone H3. NSD duplication is associated with short stature, microcephaly, intellectual…”
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Drosophila DJ-1 decreases neural sensitivity to stress by negatively regulating Daxx-like protein through dFOXO
Published in PLoS genetics (01-04-2013)“…DJ-1, a Parkinson's disease (PD)-associated gene, has been shown to protect against oxidative stress in Drosophila. However, the molecular mechanism underlying…”
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