Search Results - "KWANG IL NAM"
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The application of flipped learning to a gross anatomy dissection course
Published in PloS one (13-02-2024)“…We implemented flipped learning for a gross anatomy dissection course and compared its effects on students' motivation and academic achievement with those of…”
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Generation of electrical power under human skin by subdermal solar cell arrays for implantable bioelectronic devices
Published in Biosensors & bioelectronics (15-06-2017)“…Medical electronic implants can significantly improve people's health and quality of life. These implants are typically powered by batteries, which usually…”
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Peer-Assisted Learning in a Gross Anatomy Dissection Course
Published in PloS one (13-11-2015)“…Peer-assisted learning encourages students to participate more actively in the dissection process and promotes thoughtful dissection. We implemented…”
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Endoplasmic Reticulum-Bound Transcription Factor CREBH Stimulates RANKL-Induced Osteoclastogenesis
Published in The Journal of immunology (1950) (01-03-2018)“…Endoplasmic reticulum (ER) stress is triggered by various metabolic factors, such as cholesterol and proinflammatory cytokines. Recent studies have revealed…”
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Regulation of MDM2 E3 ligase-dependent vascular calcification by MSX1/2
Published in Experimental & molecular medicine (01-11-2021)“…Vascular calcification increases morbidity and mortality in patients with cardiovascular and renal diseases. Previously, we reported that histone deacetylase 1…”
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Distribution of the tensor of the vastus intermedius
Published in Clinical anatomy (New York, N.Y.) (01-05-2023)“…The tensor of the vastus intermedius (TVI) was first described by Grob et al. in 2016. It originates from the anteroinferior greater trochanter and inserts…”
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MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification
Published in Nature communications (01-02-2016)“…Vascular calcification (VC) is often associated with cardiovascular and metabolic diseases. However, the molecular mechanisms linking VC to these diseases have…”
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Inhibition of heat shock protein 70 blocks the development of cardiac hypertrophy by modulating the phosphorylation of histone deacetylase 2
Published in Cardiovascular research (01-11-2019)“…Abstract Aims Previously, we reported that phosphorylation of histone deacetylase 2 (HDAC2) and the resulting activation causes cardiac hypertrophy. Through…”
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miR-27a-3p Targets ATF3 to Reduce Calcium Deposition in Vascular Smooth Muscle Cells
Published in Molecular therapy. Nucleic acids (04-12-2020)“…Vascular calcification, the ectopic deposition of calcium in blood vessels, develops in association with various metabolic diseases and atherosclerosis and is…”
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Adaptor protein CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation
Published in Experimental & molecular medicine (25-09-2019)“…The adaptor protein CrkII is involved in several biological activities, including mitogenesis, phagocytosis, and cytoskeleton reorganization. Previously, we…”
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STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis
Published in Scientific reports (03-08-2016)“…Among the diverse cytokines involved in osteoclast differentiation, interleukin (IL)-3 inhibits RANKL-induced osteoclastogenesis. However, the mechanism…”
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Casein Kinase-2α1 Induces Hypertrophic Response by Phosphorylation of Histone Deacetylase 2 S394 and its Activation in the Heart
Published in Circulation (New York, N.Y.) (31-05-2011)“…Cardiac hypertrophy is characterized by transcriptional reprogramming of fetal gene expression, and histone deacetylases (HDACs) are tightly linked to the…”
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Circular RNA circSMAD4 regulates cardiac fibrosis by targeting miR-671-5p and FGFR2 in cardiac fibroblasts
Published in Molecular therapy. Nucleic acids (12-12-2023)“…Heart failure is a leading cause of death and is often accompanied by activation of quiescent cardiac myofibroblasts, which results in cardiac fibrosis. In…”
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Role of CrkII Signaling in RANKL-Induced Osteoclast Differentiation and Function
Published in The Journal of immunology (1950) (01-02-2016)“…Rac1, a member of small GTPases, is a key regulator of osteoclast differentiation and function. The Crk family adaptor proteins, consisting of Src homology…”
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Sodium Valproate, a Histone Deacetylase Inhibitor, but Not Captopril, Prevents Right Ventricular Hypertrophy in Rats
Published in Circulation Journal (2010)“…Background: Although right ventricular hypertrophy (RVH) is an adaptive process to stresses such as outflow tract obstruction, uncorrected persistent RVH often…”
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PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart
Published in Experimental & molecular medicine (26-07-2018)“…Cardiac hypertrophy occurs in response to increased hemodynamic demand and can progress to heart failure. Identifying the key regulators of this process is…”
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Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance
Published in Nucleic acids research (01-10-2010)“…The dynamic exchange of histone lysine methylation status by histone methyltransferases and demethylases has been previously implicated as an important factor…”
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Enhancer of Polycomb1, a Novel Homeodomain Only Protein-binding Partner, Induces Skeletal Muscle Differentiation
Published in The Journal of biological chemistry (09-03-2007)“…Homeodomain only protein, Hop, is an unusual small protein that modulates target gene transcription without direct binding to DNA. Here we show that Hop…”
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Enhancer of Polycomb1 Acts on Serum Response Factor to Regulate Skeletal Muscle Differentiation
Published in The Journal of biological chemistry (12-06-2009)“…Skeletal muscle differentiation is well regulated by a series of transcription factors. We reported previously that enhancer of polycomb1 (Epc1), a chromatin…”
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S-Nitrosylation of Histone Deacetylase 2 by Neuronal Nitric Oxide Synthase as a Mechanism of Diastolic Dysfunction
Published in Circulation (New York, N.Y.) (11-05-2021)“…Although the clinical importance of heart failure with preserved ejection fraction has been extensively explored, most therapeutic regimens, including nitric…”
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