Search Results - "KUZNICKI, J"

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer’s Disease by Hadar, A., Milanesi, E., Walczak, M., Puzianowska-Kuźnicka, M., Kuźnicki, J., Squassina, A., Niola, P., Chillotti, C., Attems, J., Gozes, I., Gurwitz, D.

“…Alzheimer’s Disease (AD) is the most common cause of dementia in the elderly. Centenarians – reaching the age of >100 years while maintaining good cognitive…”
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Polyelectrolyte membrane scaffold sustains growth of neuronal cells by Grzeczkowicz, A., Gruszczynska‐Biegala, J., Czeredys, M., Kwiatkowska, A., Strawski, M., Szklarczyk, M., Koźbiał, M., Kuźnicki, J., Granicka, L. H.

“…Cell immobilization within nano‐thin polymeric shells can provide an optimal concentration of biological material in a defined space and facilitate its…”
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Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain by Nagalski, A., Irimia, M., Szewczyk, L., Ferran, J. L., Misztal, K., Kuznicki, J., Wisniewska, M. B.

“…β-Catenin signaling, leading to the activation of lymphoid enhancer-binding factor 1/T cell factor (LEF1/TCF) transcription factors, plays a well-established…”
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S.04.02 Abnormal myelin and axonal integrity in St8sia2 knockout mice – a model of polysialylation deficiency by Wisniewska, M.B, Szewczyk, L.M, Nagalski, A, Hildebrandt, H, Kuznicki, J

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Conformationally altered p53: a novel Alzheimer's disease marker? by Lanni, C, Racchi, M, Mazzini, G, Ranzenigo, A, Polotti, R, Sinforiani, E, Olivari, L, Barcikowska, M, Styczynska, M, Kuznicki, J, Szybinska, A, Govoni, S, Memo, M, Uberti, D

“…The identification of biological markers of Alzheimer's disease (AD) can be extremely useful to improve diagnostic accuracy and/or to monitor the efficacy of…”
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Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer’s disease by Honarnejad, K, Daschner, A, Gehring, A P, Szybinska, A, Giese, A, Kuznicki, J, Bracher, F, Herms, J

“…Alzheimer’s disease (AD) is a progressive neurodegenerative brain disorder and the most frequent cause of dementia. To date, there are only a few approved…”
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Calcyclin (S100A6) Binding Protein (CacyBP) Is Highly Expressed in Brain Neurons by Jastrzebska, Beata, Filipek, Anna, Nowicka, Dorota, Kaczmarek, Leszek, Kuznicki, Jacek

“…The expression of a novel calcyclin (S100A6) binding protein (CacyBP) in different rat tissues was determined by Western and Northern blotting. Polyclonal…”
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Bioimpedance spectroscopy technique : intra-, extracellular, and total body water by ARMSTRONG, L. E, KENEFICK, R. W, CASTELLANI, J. W, RIEBE, D, KAVOURAS, S. A, KUZNICKI, J. T, MARESH, C. M

“…The purpose of this study was to test the validity of a multiple frequency bioimpedance spectroscopy (BIS) technique that estimates extracellular fluid volume…”
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The -22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer's disease in Poland by Zekanowski, C, Religa, D, Safranow, K, Maruszak, A, Dziedziejko, V, Styczyńska, M, Gacia, M, Golan, M, Pepłońska, B, Chlubek, D, Kuźnicki, J, Barcikowska, M

“…The -22c/t polymorphism in the promoter of the presenilin 1 gene is associated with increased risk for Alzheimer's disease (AD) in some populations. It was…”
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The Alzheimer disease-related calcium-binding protein Calmyrin is present in human forebrain with an altered distribution in Alzheimer's as compared to normal ageing brains by Bernstein, H.-G., Blazejczyk, M., Rudka, T., Gundelfinger, E. D., Dobrowolny, H., Bogerts, B., Kreutz, M. R., Kuznicki, J., Wojda, U.

“…The EF‐hand calcium binding protein Calmyrin (also called CIB‐1) was shown to interact with presenilin‐2 (PS‐2), suggesting that this interaction might play a…”
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The expression of calretinin in transfected PC12 cells provides no protection against Ca2+-overload or trophic factor deprivation by Kuźnicki, J., Isaacs, K.R., Jacobowitz, D.M.

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A model for target protein binding to calcium-activated S100 dimers by Groves, Patrick, Finn, Bryan E, Kuźnicki, Jacek, Forsén, Sture

“…S100 proteins are a family of dimeric calcium-binding proteins implicated in several cancers and neurological diseases. Calbindin D 9k is an unusual monomeric…”
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Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons by Maciąg, Filip, Majewski, Łukasz, Boguszewski, Paweł M., Gupta, Rishikesh Kumar, Wasilewska, Iga, Wojtaś, Bartosz, Kuznicki, Jacek

“…Orai proteins form highly selective Ca2+ release-activated channels (CRACs). They play a critical role in store-operated Ca2+ entry (SOCE; i.e., the influx of…”
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Proteins of GSK3 beta pathways as targets for AD drugs by Kuznicki, J

“…GSK3 beta is suggested to be a key enzyme for the development of AD. This kinase phosphorylates beta -catenin and then labels it for subsequent ubiquitylation…”
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Regulation of cell specific expression of calcyclin (S100A6) in nerve cells and other tissues by Leśniak, W, Swart, G W, Bloemers, H P, Kuźnicki, J

“…Many of the small, acidic, calcium binding S100 proteins present in the brain specifically map different anatomical regions and cell types and their…”
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Molecular Cloning and Expression of a Mouse Brain cDNA Encoding a Novel Protein Target of Calcyclin by Filipek, Anna, Kuźnicki, Jacek

“…: A protein target of mouse calcyclin, p30, which we call calcyclin‐binding protein (CacyBP), was identified in mouse brain and Ehrlich ascites tumor (EAT)…”
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Endogenous STIM2 and endogenous ORAI1 form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons by Gruszczynska-Biegala, J, Kuznicki, J

“…ER calcium sensors (STIM1, STIM2) and calcium channel-ORAI1 interaction is crucial for store-operated calcium entry (SOCE) in non-excitable cells, but in…”
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Cognitive performance and functional status are the major factors predicting survival of centenarians in Poland by Mossakowska, Malgorzata, Broczek, Katarzyna, Wieczorowska-Tobis, Katarzyna, Klich-Rączka, Alicja, Jonas, Marta, Pawlik-Pachucka, Eliza, Safranow, Krzysztof, Kuznicki, Jacek, Puzianowska-Kuznicka, Monika

“…Clinical and biochemical predictors of extreme longevity would be useful in geriatric practice but have still not been clearly defined. To identify the best…”
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Antibody recognition of calcium-binding proteins depends on their calcium-binding status by Winsky, L, Kuźnicki, J

“…Previous studies have revealed changes in immunohistochemical stains for calcium-binding proteins after manipulations that influence intracellular calcium…”
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Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington's Disease by Czeredys, Magdalena, Vigont, Vladimir A, Boeva, Vasilisa A, Mikoshiba, Katsuhiko, Kaznacheyeva, Elena V, Kuznicki, Jacek

“…Huntington's disease (HD) is a hereditary neurodegenerative disease that is caused by polyglutamine expansion within the huntingtin (HTT) gene. One of the…”
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