Search Results - "KUWASHIMA, N"

Sequential delivery of interferon-α gene and DCs to intracranial gliomas promotes an effective antitumor response by TSUGAWA, T, KUWASHIMA, N, POLLACK, I. F, OKADA, H, SATO, H, FELLOWS-MAYLE, W. K, DUSAK, J. E, OKADA, K, PAPWORTH, G. D, WATKINS, S. C, GAMBOTTO, A, YOSHIDA, J

“…Effective presentation of tumor antigens by dendritic cells (DCs) is considered to be essential for the induction of antitumor T-cell responses. Apoptotic and…”
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Organ-specific adhesion of neuroblastoma cells in vitro: Correlation with their hepatic metastasis potential by Kuwashima, Naruo

“…Neuroblastoma (NB) is the most common solid malignant tumor found in pediatric patients and the liver is one of the major sites of metastasis. To investigate…”
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EphA2 as a Glioma-Associated Antigen: A Novel Target for Glioma Vaccines by Hatano, Manabu, Eguchi, Junichi, Tatsumi, Tomohide, Kuwashima, Naruo, Dusak, Jill E., Kinch, Michel S., Pollack, Ian F., Hamilton, Ronald L., Storkus, Walter J., Okada, Hideho

“…EphA2 is a receptor tyrosine kinase, is frequently overexpressed in a wide array of advanced cancers. We demonstrate in the current study that the EphA2…”
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Epidermal growth factor receptor-transfected bone marrow stromal cells exhibit enhanced migratory response and therapeutic potential against murine brain tumors by Sato, Hidemitsu, Kuwashima, Naruo, Sakaida, Tsukasa, Hatano, Manabu, Dusak, Jill E, Fellows-Mayle, Wendy K, Papworth, Glenn D, Watkins, Simon C, Gambotto, Andrea, Pollack, Ian F, Okada, Hideho

“…We have created a novel cellular vehicle for gene therapy of malignant gliomas by transfection of murine bone marrow stroma cells (MSCs) with a cDNA encoding…”
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IL-4-Transfected Tumor Cell Vaccines Activate Tumor-Infiltrating Dendritic Cells and Promote Type-1 Immunity by Eguchi, Junichi, Kuwashima, Naruo, Hatano, Manabu, Nishimura, Fumihiko, Dusak, Jill E, Storkus, Walter J, Okada, Hideho

“…We previously demonstrated that IL-4 gene-transfected glioma cell vaccines induce effective therapeutic immunity in preclinical glioma models, and have…”
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Delivery of dendritic cells engineered to secrete IFN-alpha into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines: dependence on apoptotic pathways by Kuwashima, Naruo, Nishimura, Fumihiko, Eguchi, Junichi, Sato, Hidemitsu, Hatano, Manabu, Tsugawa, Takahiko, Sakaida, Tsukasa, Dusak, Jill E, Fellows-Mayle, Wendy K, Papworth, Glenn D, Watkins, Simon C, Gambotto, Andrea, Pollack, Ian F, Storkus, Walter J, Okada, Hideho

“…We tested whether modulation of the CNS-tumor microenvironment by delivery of IFN-alpha-transduced dendritic cells (DCs: DC-IFN-alpha) would enhance the…”
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Delivery of interferon-α transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines by OKADA, Hideho, TSUGAWA, Takahiko, CHAMBERS, William H, POTTER, Douglas M, STORKUS, Walter J, POLLACK, Ian F, SATO, Hidemitsu, KUWASHIMA, Naruo, GAMBOTTO, Andrea, OKADA, Kaori, DUSAK, Jill E, FELLOWS-MAYLE, Wendy K, PAPWORTH, Glenn D, WATKINS, Simon C

“…We evaluated the effects, on immunity and survival, of injection of interferon (IFN)-alpha-transfected dendritic cells (DC-IFN-alpha) into intracranial tumors…”
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Gene therapy and biologic therapy with interleukin-4 by Okada, Hideho, Kuwashima, Naruo

“…For more than two decades, there has been a concerted effort to define the biology of, and develop the clinical applications for, cytokines that influence the…”
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An investigation on the educational state of the legal medicine in medical college 1968 by Kuwashima, N, Naitow, M

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Successful in utero gene transfer using a gene gun in midgestational mouse fetuses by Yoshizawa, Jyoji, Li, Xiano-Kand, Fujino, Masayuki, Kimura, Hiromitu, Mizuno, Ryoji, Hara, Akihiko, Ashizuka, Syuichi, Kanai, Masaki, Kuwashima, Naruo, Kurobe, Masashi, Yamazaki, Yoji

“…In utero gene therapy offers a number of potential advantages over postnatal gene therapy. A latest method of gene transfer to fetuses in utero uses a new tool…”
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Sequential delivery of interferon-[alpha] gene and DCs to intracranial gliomas promotes an effective antitumor response by Tsugawa, T, Kuwashima, N, Sato, H, Fellows-Mayle, W K, Dusak, J E, Okada, K, Papworth, G D, Watkins, S C, Gambotto, A, Yoshida, J, Pollack, I F, Okada, H

“…Effective presentation of tumor antigens by dendritic cells (DCs) is considered to be essential for the induction of antitumor T-cell responses. Apoptotic and…”
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CD40 Ligand Immunotherapy in Cancer: An Efficient Approach by Kuwashima, Naruo, Kageyama, Shigeru, Eto, Yoshikatsu, Urashima, Mitsuyoshi

“…Cancer cells do not elicit a clinically sufficient anti-tumor immune response that results in tumor rejection. Recently, many investigators have been trying to…”
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Inhibitory Effect of TNP-470 on Hepatic Metastasis of Mouse Neuroblastoma by Yoshizawa, Jyoji, Mizuno, Ryoji, Yoshida, Tsuginori, Hara, Akihiko, Ashizuka, Syuichi, Kanai, Masaki, Kuwashima, Naruo, Kurobe, Masashi, Yamazaki, Yoji

“…Purpose. TNP-470 is a strong inhibitor of angiogenesis. The present study was designed to determine whether the angiogenesis inhibitor TNP-470 inhibits…”
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In vivo function of homing receptors participating in lymphocyte recirculation: transfer analysis in SCID mice by Saito, S, Kuwashima, N, Koizumi, H, Nomura, T, Yagita, H, Okumura, K, Sonoda, A, Tadakuma, T, Tanaka, H

“…In order to examine the in vivo function of the adhesion molecules implicated in lymphocyte homing, blocking effects of antibodies against various adhesion…”
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