Search Results - "KUROSAKI, Yuji"
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A Retinoid X Receptor Agonist Directed to the Large Intestine Ameliorates T-Cell-Mediated Colitis in Mice
Published in Frontiers in pharmacology (12-08-2021)“…Retinoid X receptor (RXR) is a nuclear receptor that heterodimerizes with several nuclear receptors, integrating ligand-mediated signals across the…”
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2
Population Pharmacokinetic Analysis of Vancomycin Using Serum Cystatin C as a Marker of Renal Function
Published in Antimicrobial Agents and Chemotherapy (01-02-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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3
In vivo application of chitosan to facilitate intestinal acyclovir absorption in rats
Published in Journal of pharmaceutical sciences (01-07-2012)“…The effect of chitosan on the intestinal absorption of acyclovir (ACV) was evaluated in rats, and factors influencing its facilitative effect on the ACV…”
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Pharmacokinetic analysis of new synthetic antimalarial N-251
Published in Tropical medicine and health (05-07-2019)“…With the emergence and growing number of drug-resistant , a new drug for malaria control must be urgently developed. The new antimalarial synthetic compound…”
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Effects of Peritoneal Dialysis on Pharmacotherapy: A Deductive Pharmacokinetic-model Approach to Predict Drug Concentration Profiles in Plasma and Peritoneal Fluid
Published in DRUG METABOLISM AND PHARMACOKINETICS (2014)“…The aim of this study was to present a deductive compartment pharmacokinetic (PK) model to predict the concentration profiles of drugs in plasma and peritoneal…”
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6
Potential of synthetic endoperoxides against Trichomonas vaginalis in vitro
Published in Parasitology international (01-10-2017)“…Abstract Metronidazole is well known for medicine against Trichomonas vaginalis infection, but it has side effects though it is effective, and especially…”
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7
Asymmetric synthesis of 3-substituted 3,4-dihydroisocoumarins via stereoselective addition of laterally lithiated chiral 2-( o-tolyl)oxazolines to aldehydes followed by diastereomer-selective lactonization
Published in Tetrahedron (28-03-2005)“…Lateral lithiation of ( S)-4-isopropyl-2-( o-tolyl)oxazoline in diethyl ether followed by the reaction with aldehydes in the presence of TMEDA produced the…”
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8
Chronic Hyperinsulinemia Enhances Adrenergic Vasoconstriction and Decreases Calcitonin Gene-Related Peptide-Containing Nerve-Mediated Vasodilation in Pithed Rats
Published in Hypertension research (01-05-2006)“…The present study investigated the influence of chronic hyperinsulinemia on vascular responsiveness induced by adrenergic nerves and calcitonin gene-related…”
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9
Empirical Approach for Improved Estimation of Unbound Serum Concentrations of Valproic Acid in Epileptic Infants by Considering Their Physical Development
Published in Biological & pharmaceutical bulletin (01-01-2011)“…The unbound serum concentration of valproic acid (VPA) is closely related to its therapeutic efficacy. In epileptic infants, the unbound VPA concentration…”
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10
Effects of Capsaicin on Intestinal Cephalexin Absorption in Rats
Published in Biological & Pharmaceutical Bulletin (01-03-2007)“…The effects of capsaicin on intestinal cephalexin absorption were investigated by means of in situ single pass perfusion in rats to clarify whether this…”
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11
Pharmacodynamic Characterization of Nitric Oxide-Mediated Vasodilatory Activity in Isolated Perfused Rat Mesenteric Artery Bed
Published in Biological & Pharmaceutical Bulletin (2011)“…Vasodilation profiles following a short-term infusion of nitric oxide (NO), acetylcholine (ACh), and sodium nitroprusside (SNP) into an isolated perfused…”
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12
Comparative study of increased plasma quinidine concentration in rats with glycerol- and cisplatin-induced acute renal failure
Published in Drug metabolism and pharmacokinetics (2009)“…A comparative study of altered plasma concentration of quinidine in rats with glycerol- and cisplatin-induced acute renal failure (ARF) was conducted with…”
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13
Long-Term Inhibition of Angiotensin Prevents Reduction of Periarterial Innervation of Calcitonin Gene-Related Peptide (CGRP)-Containing Nerves in Spontaneously Hypertensive Rats
Published in Hypertension research (01-05-2005)“…The aim of this study was to investigate age-related changes in the density of calcitonin gene-related peptide (CGRP)-containing nerve fibers in spontaneously…”
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14
Comparison of individual perceptions of medication costs and benefits between intentional and unintentional medication non-adherence among Japanese patients
Published in Patient education and counseling (01-02-2008)“…Abstract Objective To identify Japanese patients’ perceptions of the costs and benefits of their medications by administering a questionnaire validated in…”
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15
Application of the Correlation of in Vitro Dissolution Behavior and in Vivo Plasma Concentration Profile (IVIVC) for Soft-Gel Capsules—a Pointless Pursuit?
Published in Biological & Pharmaceutical Bulletin (01-11-2007)“…Plasma concentration profiles of arundic acid ((R)-(−)-2-propyloctanoic acid), an oil-like medicine, administered as soft-gel capsules in human clinical tests…”
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16
Pharmacokinetic properties of newly synthesized retinoid X receptor agonists possessing a 6-[N-ethyl-N-(3-alkoxy-4-isopropylphenyl)amino]nicotinic acid skeleton in rats
Published in Drug development and industrial pharmacy (01-09-2011)“…Objective: The pharmacokinetic properties of three newly synthesized retinoid X receptor (RXR) agonists were evaluated in rats to elucidate the structural…”
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17
Pharmacokinetic analysis of flomoxef in children undergoing cardiopulmonary bypass and modified ultrafiltration
Published in General thoracic and cardiovascular surgery (01-04-2008)“…Objective Cardiopulmonary bypass (CPB) induces changes in the pharmacokinetics of drugs. The purpose of this study was to model the pharmacokinetics of…”
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Vanilloid receptors mediate adrenergic nerve‐ and CGRP‐containing nerve‐dependent vasodilation induced by nicotine in rat mesenteric resistance arteries
Published in British journal of pharmacology (01-08-2004)“…Previous studies showed that nicotine induces adrenergic nerve‐dependent vasodilation that is mediated by endogenous calcitonin gene‐related peptide (CGRP)…”
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Capsaicin-Induced Increase of Intestinal Cefazolin Absorption in Rats
Published in DRUG METABOLISM AND PHARMACOKINETICS (01-01-2007)“…The effect of capsaicin on intestinal cefazolin absorption was examined by means of an in situ closed loop method in rats to clarify whether the vanilloid…”
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20
Efficacy of peritoneal dialysis of tolbutamide in rats under conditions of the plasma unbound fraction being increased
Published in Biopharmaceutics & drug disposition (01-01-2009)“…Peritoneal dialysis of a highly protein‐bound compound, tolbutamide, was examined in rats to clarify whether the efficacy of the peritoneal dialysis of such…”
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