Search Results - "KUROME, M"

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy by Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A. B., Bozoglu, T., Baehr, A., Schneider, C. M., Sinnecker, D., Klett, K., Fröhlich, T., Rahman, F. Abdel, Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M. C., Klymiuk, N., Laugwitz, K. L., Wolf, E., Wurst, W., Kupatt, C.

“…Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients…”
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Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis by Klymiuk, N., Mundhenk, L., Kraehe, K., Wuensch, A., Plog, S., Emrich, D., Langenmayer, M. C., Stehr, M., Holzinger, A., Kröner, C., Richter, A., Kessler, B., Kurome, M., Eddicks, M., Nagashima, H., Heinritzi, K., Gruber, A. D., Wolf, E.

“…Cystic fibrosis (CF) is the most common lethal inherited disease in Caucasians and is caused by mutations in the CFTR gene. The disease is incurable and…”
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Birth of offspring following transplantation of cryopreserved immature testicular pieces and in-vitro microinsemination by Shinohara, T., Inoue, K., Ogonuki, N., Kanatsu-Shinohara, M., Miki, H., Nakata, K., Kurome, M., Nagashima, H., Toyokuni, S., Kogishi, K., Honjo, T., Ogura, A.

“…BACKGROUND: Fertility protection is an urgent clinical problem for prepubertal male oncology patients who undergo either chemotherapy or radiotherapy. As these…”
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G.P.82 by Walter, M.C, Klymiuk, N, Blutke, A, Graf, A, Krause, S, Wuensch, A, Krebs, S, Kessler, B, Zakhartchenko, V, Kurome, M, Kemter, E, Nagashima, H, Schoser, B, Herbach, N, Blum, H, Wanke, R, Aartsma-Rus, A, Lochmuller, H, Wolf, E

“…Duchenne muscular dystrophy (DMD) is caused by mutations in the X-linked dystrophin (DMD) gene. The absence of dystrophin protein leads to progressive muscle…”
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Predictive factors of efficacy of leukocytapheresis for steroid-resistant ulcerative colitis patients by Takemoto, K, Kato, J, Kuriyama, M, Nawa, T, Kurome, M, Okada, H, Sakaguchi, K, Shiratori, Y

“…Abstract Background The effectiveness of leukocytapheresis against ulcerative colitis has been reported. However, the efficacy of this therapy for…”
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Hollow fiber vitrification of biopsied in vitro produced bovine blastocysts by Beck, A, Kurome, M, Nagashima, H, Reichenbach, M, Reichenbach, H.D, Wolf, E

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Transgenic strategies to overcome cell-mediated and acute vascular rejection of pig-to-human xenografts by Klymiuk, N., Keßler, B., Kurome, M., Wuensch, A., Wolf, E.

“…The development of α(1,3)‐galactosyltransferase deficient pigs along with overexpression of complement regulatory proteins was an important step to overcome…”
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New transgenic pigs for xenotransplantation, part 2: Strategies to overcome cellular rejection by Keßler, B., Kurome, M., Klymiuk, N., Wünsch, A., Seissler, J., Wolf, E.

“…The successful generation of α‐1,3 galactosyltransferase knockout (αGal‐KO) pigs and pigs expressing human complement regulators was a crucial step forward in…”
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Development of efficient strategies for the production of genetically modified pigs by Nagashima, H, Fujimura, T, Takahagi, Y, Kurome, M, Wako, N, Ochiai, T, Esaki, R, Kano, K, Saito, S, Okabe, M, Murakami, H

“…Although pronuclear DNA micro-injection has long been the most reliable method to produce transgenic pigs, the efficiency of production of transgenic offspring…”
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Establishment of genetically modified pig animal models for xenotransplantation by Klymiuk, N., Kessler, B., Kurome, M., Wünsch, A., Wolf, E.

“…Due to the shortage of available human donor organs, xenotransplantation is an alternative to allotransplanation. Pig is the favoured donor animal because of…”
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Expression of Human Thrombomodulin on the Endothelium of Pig Xenograft Donors: 2350 by Wuensch, A., Klymiuk, N., Kurome, M., Kessler, B., Baehr, A., Nagashima, H., Ayares, D., Wolf, E.

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Production of Transgenic-clone Pigs by the Combination of ICSI-mediated Gene Transfer with Somatic Cell Nuclear Transfer by Kurome, M, Ueda, H, Tomii, R, Naruse, K, Nagashima, H

“…The objective of this study was to examine whether the ICSI-mediated gene transfer method using in vitro matured oocytes and frozen sperm head could actually…”
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Beta-Cell Specific Expression of LEA29Y Prevents Cellular Rejection in Islet Xenotransplantation: 2347 by Baehr, A., Wuensch, A., van Bürck, L., Kurome, M., Kessler, B., Nagashima, H., Seissler, J., Klymiuk, N., Wolf, E.

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Phenotypic Characterization of Diabetic INSC94Y Transgenic Pigs: 2502 by Renner, S., Braun, C., Blutke, A., Herbach, N., Wuensch, A., Kessler, B., Kurome, M., Krebs, S., Puk, O., Nagashima, H., Graw, J., Blum, H., Wanke, R., Wolf, E.

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Phenotypic Characterization of Diabetic INSC94Y Transgenic Pigs: 2502 by Renner, S., Braun, C., Blutke, A., Herbach, N., Wuensch, A., Kessler, B., Kurome, M., Krebs, S., Puk, O., Nagashima, H., Graw, J., Blum, H., Wanke, R., Wolf, E.

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G.P.82: Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle by Walter, M.C., Klymiuk, N., Blutke, A., Graf, A., Krause, S., Wuensch, A., Krebs, S., Kessler, B., Zakhartchenko, V., Kurome, M., Kemter, E., Nagashima, H., Schoser, B., Herbach, N., Blum, H., Wanke, R., Aartsma-Rus, A., Lochmuller, H., Wolf, E.

“…Duchenne muscular dystrophy (DMD) is caused by mutations in the X-linked dystrophin (DMD) gene. The absence of dystrophin protein leads to progressive muscle…”
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Cryopreservation of Porcine Embryos Derived from In Vitro-Matured Oocytes by ESAKI, Ritsuko, UEDA, Hideto, KUROME, Mayuko, HIRAKAWA, Kazumasa, TOMII, Ryo, YOSHIOKA, Hiroki, USHIJIMA, Hitoshi, KUWAYAMA, Masashige, NAGASHIMA, Hiroshi

“…This study describes a cryopreservation method for porcine in vitro-produced (IVP) embryos using as a model parthenogenetic embryos derived from in…”
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Generation and Characterization of a Porcine Model of Duchenne Muscular Dystrophy by Blutke, A., Klymiuk, N., Graf, A., Krause, S., Burkhardt, K., Wuensch, A., Krebs, S., Kessler, B., Zakhartchenko, V., Kurome, M., Kemter, E., Nagashima, H., Schoser, B., Herbach, N., Blum, H., Wanke, R., Thirion, C., Lochmüller, H., Walter, M.C., Wolf, E.

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Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis: Evolutionary Medicine by KLYMIUK, N, MUNDHENK, L, RICHTER, A, KESSLER, B, KUROME, M, EDDICKS, M, NAGASHIMA, H, HEINRITZI, K, GRUBER, A. D, WOLF, E, KRAEHE, K, WUENSCH, A, PLOG, S, EMRICH, D, LANGENMAYER, M. C, STEHR, M, HOLZINGER, A, KRÖNER, C

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Production of transgenic and non-transgenic clones in miniature pigs by somatic cell nuclear transfer by Kurome, M.(Meiji Univ., Kawasaki, Kanagawa (Japan)), Ishikawa, T, Tomii, R, Ueno, S, Shimada, A, Yazawa, H, Nagashima, H

“…Miniature pigs have been recognized as valuable experimental animals in various fields such as medical and pharmaceutical research. However, the amount of…”
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