Search Results - "KUROKI, Ryota"

Grating-Based Surface Plasmon Resonance Sensor for Visible Light Employing a Metal/Semiconductor Junction for Electrical Readout by Kuroki, Ryota, Suzuki, Shinichi, Yasunaga, Shun, Oshita, Masaaki, Kan, Tetsuo

“…In this study, we proposed an electrical readout surface plasmon resonance (SPR) chemical sensor coupled with visible light to avoid significant light…”
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Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9 by Maekawa, Keiko, Adachi, Motoyasu, Matsuzawa, Yumiko, Zhang, Qinghai, Kuroki, Ryota, Saito, Yoshiro, Shah, Manish B

“…Single-nucleotide polymorphisms in drug-metabolizing cytochrome P450 (CYP) enzymes are important contributors to interindividual differences in drug metabolism…”
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Structural basis for acceptor‐substrate recognition of UDP‐glucose: anthocyanidin 3‐O‐glucosyltransferase from Clitoria ternatea by Hiromoto, Takeshi, Honjo, Eijiro, Noda, Naonobu, Tamada, Taro, Kazuma, Kohei, Suzuki, Masahiko, Blaber, Michael, Kuroki, Ryota

“…UDP‐glucose: anthocyanidin 3‐O‐glucosyltransferase (UGT78K6) from Clitoria ternatea catalyzes the transfer of glucose from UDP‐glucose to anthocyanidins such…”
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Low-barrier hydrogen bond in photoactive yellow protein by Yamaguchi, Shigeo, Kamikubo, Hironari, Kurihara, Kazuo, Kuroki, Ryota, Niimura, Nobuo, Shimizu, Nobutaka, Yamazaki, Yoichi, Kataoka, Mikio

“…Low-barrier hydrogen bonds (LBHBs) have been proposed to play roles in protein functions, including enzymatic catalysis and proton transfer. Transient…”
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Neutron crystallography of copper amine oxidase reveals keto/enolate interconversion of the quinone cofactor and unusual proton sharing by Murakawa, Takeshi, Kurihara, Kazuo, Shoji, Mitsuo, Shibazaki, Chie, Sunami, Tomoko, Tamada, Taro, Yano, Naomine, Yamada, Taro, Kusaka, Katsuhiro, Suzuki, Mamoru, Shigeta, Yasuteru, Kuroki, Ryota, Hayashi, Hideyuki, Yano, Takato, Tanizawa, Katsuyuki, Adachi, Motoyasu, Okajima, Toshihide

“…Recent advances in neutron crystallographic studies have provided structural bases for quantum behaviors of protons observed in enzymatic reactions. Thus, we…”
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Anti‐FGF23 Neutralizing Antibodies Show the Physiological Role and Structural Features of FGF23 by Yamazaki, Yuji, Tamada, Taro, Kasai, Noriyuki, Urakawa, Itaru, Aono, Yukiko, Hasegawa, Hisashi, Fujita, Toshiro, Kuroki, Ryota, Yamashita, Takeyoshi, Fukumoto, Seiji, Shimada, Takashi

“…Fibroblast growth factor (FGF)23 is proposed to play a physiological role in the regulation of phosphate and vitamin D metabolism; deranged circulatory levels…”
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A dinuclear Ni(μ-H)Ru complex derived from H2 by OGO, Seiji, KABE, Ryota, TAMADA, Taro, KUROKI, Ryota, UEHARA, Keiji, KURE, Bunsho, NISHIMURA, Takashi, MENON, Saija C, HARADA, Ryosuke, FUKUZUMI, Shunichi, HIGUCHI, Yoshiki, OHHARA, Takashi

“…Models of the active site in [NiFe]hydrogenase enzymes have proven challenging to prepare. We isolated a paramagnetic dinuclear nickel-ruthenium complex with a…”
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TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2 by Tamada, Taro, Shinmi, Daisuke, Ikeda, Masahiro, Yonezawa, Yasushi, Kataoka, Shiro, Kuroki, Ryota, Mori, Eiji, Motoki, Kazuhiro

“…The fully human monoclonal antibody KMTR2 acts as a strong direct agonist for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor 2…”
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Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallography by Adachi, Motoyasu, Ohhara, Takashi, Kurihara, Kazuo, Tamada, Taro, Honjo, Eijiro, Okazaki, Nobuo, Arai, Shigeki, Shoyama, Yoshinari, Kimura, Kaname, Matsumura, Hiroyoshi, Sugiyama, Shigeru, Adachi, Hiroaki, Takano, Kazufumi, Mori, Yusuke, Hidaka, Koushi, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki, Kuroki, Ryota

“…HIV-1 protease is a dimeric aspartic protease that plays an essential role in viral replication. To further understand the catalytic mechanism and inhibitor…”
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Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions by Hiromoto, Takeshi, Ikura, Teikichi, Honjo, Eijiro, Blaber, Michael, Kuroki, Ryota, Tamada, Taro

“…Protein crystals are generally fragile and sensitive to subtle changes such as pH, ionic strength, and/or temperature in their crystallization mother liquor…”
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Combined High-Resolution Neutron and X-ray Analysis of Inhibited Elastase Confirms the Active-Site Oxyanion Hole but Rules against a Low-Barrier Hydrogen Bond by Tamada, Taro, Kinoshita, Takayoshi, Kurihara, Kazuo, Adachi, Motoyasu, Ohhara, Takashi, Imai, Keisuke, Kuroki, Ryota, Tada, Toshiji

“…To help resolve long-standing questions regarding the catalytic activity of the serine proteases, the structure of porcine pancreatic elastase has been…”
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Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition by Kuroki, Ryota, Murata, Yui, Fuke, Satoshi, Nakachi, Yutaka, Nakashima, Jun, Kujoth, Gregory C., Prolla, Tomas A., Bundo, Miki, Kato, Tadafumi, Iwamoto, Kazuya

“…The retrotransposon long interspersed nuclear element-1 (LINE-1) can autonomously increase its copy number within a host genome through the retrotransposition…”
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Structure Analysis and Derivation of Deformed Electron Density Distribution of Polydiacetylene Giant Single Crystal by the Combination of X‑ray and Neutron Diffraction Data by Tashiro, Kohji, Kusaka, Katsuhiro, Hosoya, Takaaki, Ohhara, Takashi, Hanesaka, Makoto, Yoshizawa, Yoshinori, Yamamoto, Hiroko, Niimura, Nobuo, Tanaka, Ichiro, Kurihara, Kazuo, Kuroki, Ryota, Tamada, Taro

“…The crystal structure of polydiacetylene giant single crystal has been analyzed on the basis of the two different methods of wide-angle neutron diffraction and…”
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Homodimeric Cross-Over Structure of the Human Granulocyte Colony-Stimulating Factor (GCSF) Receptor Signaling Complex by Tamada, Taro, Honjo, Eijiro, Maeda, Yoshitake, Okamoto, Tomoyuki, Ishibashi, Matsujiro, Tokunaga, Masao, Kuroki, Ryota

“…A crystal structure of the signaling complex between human granulocyte colony-stimulating factor (GCSF) and a ligand binding region of GCSF receptor (GCSF-R),…”
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Seven Cysteine-Deficient Mutants Depict the Interplay between Thermal and Chemical Stabilities of Individual Cysteine Residues in Mitogen-Activated Protein Kinase c‑Jun N‑Terminal Kinase 1 by Nakaniwa, Tetsuko, Fukada, Harumi, Inoue, Tatsuya, Gouda, Masaki, Nakai, Ryoko, Kirii, Yasuyuki, Adachi, Motoyasu, Tamada, Taro, Segawa, Shin-ichi, Kuroki, Ryota, Tada, Toshiji, Kinoshita, Takayoshi

“…Intracellular proteins can have free cysteines that may contribute to their structure, function, and stability; however, free cysteines can lead to chemical…”
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X-ray and neutron protein crystallographic analysis of the trypsin-BPTI complex by Kawamura, Kenji, Yamada, Taro, Kurihara, Kazuo, Tamada, Taro, Kuroki, Ryota, Tanaka, Ichiro, Takahashi, Haruyuki, Niimura, Nobuo

“…In this work, the crystal structure of the β‐trypsin–bovine pancreatic trypsin inhibitor (BPTI) complex was refined and the D and H atoms in the complex were…”
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A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase by Arai, Shigeki, Yonezawa, Yasushi, Okazaki, Nobuo, Matsumoto, Fumiko, Tamada, Taro, Tokunaga, Hiroko, Ishibashi, Matsujiro, Blaber, Michael, Tokunaga, Masao, Kuroki, Ryota

“…Nucleoside diphosphate kinase (NDK) is known to form homotetramers or homohexamers. To clarify the oligomer state of NDK from moderately halophilic Halomonas…”
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Characterization of the Interaction between Interleukin-13 and Interleukin-13 Receptors by Arima, Kazuhiko, Sato, Kazuo, Tanaka, Go, Kanaji, Sachiko, Terada, Tohru, Honjo, Eijiro, Kuroki, Ryota, Matsuo, Yo, Izuhara, Kenji

“…Interleukin-13 (IL-13) possesses two types of receptor: the heterodimer, composed of the IL-13Rα1 chain (IL-13Rα1) and the IL-4Rα chain (IL-4Rα), transducing…”
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Anomalous Water Molecules and Mechanistic Effects of Water Nanotube Clusters Confined to Molecular Porous Crystals by Tadokoro, Makoto, Ohhara, Takashi, Ohhata, Yuhki, Suda, Takaaki, Miyasato, Yuji, Yamada, Takeshi, Kikuchi, Tatsuya, Tanaka, Ichiro, Kurihara, Kazuo, Oguni, Masaharu, Nakasuji, Kazuhiro, Yamamuro, Osamu, Ryota, Kuroki

“…The movement of water molecules in the limited space present within nanoscale regions, which is different from the molecular motion of bulk water, is…”
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Enhanced Apoptosis and Tumor Regression Induced by a Direct Agonist Antibody to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Receptor 2 by Motoki, Kazuhiro, Mori, Eiji, Matsumoto, Atsushi, Thomas, Mayumi, Tomura, Takafumi, Humphreys, Robin, Albert, Vivian, Muto, Mari, Yoshida, Hitoshi, Aoki, Masami, Tamada, Taro, Kuroki, Ryota, Yoshida, Hideaki, Ishida, Isao, Ware, Carl F, Kataoka, Shiro

“…Purpose: Substantial evidence indicates that supraoligomerization of the death receptors for Fas ligand and tumor necrosis factor–related apoptosis-inducing…”
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