Search Results - "KURODA, Teruo"
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The role of RND-type efflux pumps in multidrug-resistant mutants of Klebsiella pneumoniae
Published in Scientific reports (02-07-2020)“…The emergence of multidrug-resistant Klebsiella pneumoniae is a worldwide problem. K. pneumoniae possesses numerous resistant genes in its genome. We isolated…”
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Constituents of Psoralea corylifolia Fruits and Their Effects on Methicillin-Resistant Staphylococcus aureus
Published in Molecules (Basel, Switzerland) (09-07-2015)“…Two new flavonoids, bakuisoflavone (1) and bakuflavanone (2), together with 15 known compounds, were isolated from the fruits of Psoralea corylifolia, and…”
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Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae
Published in Gene (01-05-2012)“…We cloned a gene, kexD, that provides a multidrug-resistant phenotype from multidrug-resistant Klebsiella pneumoniae MGH78578. The deduced amino acid sequence…”
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Genome Mining-Based Discovery of Fungal Macrolides Modified by glycosylphosphatidylinositol (GPI)–Ethanolamine Phosphate Transferase Homologues
Published in Organic letters (07-08-2020)“…Through genome mining for fungal macrolide natural products, we discovered a characteristic family of putative macrolide biosynthetic gene clusters that…”
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Comprehensive analysis of resistance-nodulation-cell division superfamily (RND) efflux pumps from Serratia marcescens, Db10
Published in Scientific reports (19-03-2019)“…We investigated the role of the resistance-nodulation-cell division superfamily (RND) efflux system on intrinsic multidrug resistance in Serratia marcescens …”
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Effects of the order of exposure to antimicrobials on the incidence of multidrug-resistant Pseudomonas aeruginosa
Published in Scientific reports (31-05-2023)“…Multidrug-resistant Pseudomonas aeruginosa (MDRP) is one of the most important pathogens in clinical practice. To clarify the mechanisms contributing to its…”
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Viral coexistence and insertional mutations in the ORF8 region of SARS-CoV-2: A possible mechanism of nucleotide insertion
Published in Virus research (01-12-2024)“…•Virus from swab sample S66 in hiroshima had T-base insertions in the ORF8 region.•Cloning, and TIDE analysis confirmed mixed viruses with different T-base…”
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Structural Basis of H+-Dependent Conformational Change in a Bacterial MATE Transporter
Published in Structure (London) (05-02-2019)“…Multidrug and toxic compound extrusion (MATE) transporters efflux toxic compounds using a Na+ or H+ gradient across the membrane. Although the structures of…”
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Antimicrobial Activity of Oleanolic Acid from Salvia officinalis and Related Compounds on Vancomycin-Resistant Enterococci (VRE)
Published in Biological & Pharmaceutical Bulletin (01-06-2007)“…An extract from Salvia officinalis (Sage) leaves showed antimicrobial activity against vancomycin-resistant enterococci (VRE). We isolated the effective…”
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Whole-Genome and Plasmid Comparative Analysis of Campylobacter jejuni from Human Patients in Toyama, Japan, from 2015 to 2019
Published in Microbiology spectrum (14-02-2023)“…Campylobacter jejuni is a major causative agent of food poisoning, and increasing antimicrobial resistance is a concern. This study investigated 116 clinical…”
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Structure–activity relationship of indoloquinoline analogs anti-MRSA
Published in Bioorganic & medicinal chemistry letters (01-12-2015)“…[Display omitted] Indolo[3,2-b]quinoline analogs (3a–3s), 4-(acridin-9-ylamino) phenol hydrochloride (4), benzofuro[3,2-b]quinoline (3t),…”
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Ellagitannins of Davidia involucrata. I. Structure of Davicratinic Acid A and Effects of Davidia Tannins on Drug-Resistant Bacteria and Human Oral Squamous Cell Carcinomas
Published in Molecules (Basel, Switzerland) (15-03-2017)“…We isolated a new ellagitannin, davicratinic acid A ( ), together with four known ellagitannins, davidiin ( ), granatin A ( ), pedunculagin ( ), and 3-…”
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Indolo[3,2-b]quinoline Derivatives Suppressed the Hemolytic Activity of Beta-Pore Forming Toxins, Aerolysin-Like Hemolysin Produced by Aeromonas sobria and Alpha-Hemolysin Produced by Staphylococcus aureus
Published in Biological & pharmaceutical bulletin (01-01-2016)“…In an attempt to discover inhibitory compounds against pore-forming toxins, some of the major toxins produced by bacteria, we herein examined the effects of…”
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Characterization of MATE-type multidrug efflux pumps from Klebsiella pneumoniae MGH78578
Published in PloS one (25-03-2015)“…We previously described the cloning of genes related to drug resistance from Klebsiella pneumoniae MGH78578. Of these, we identified a putative gene encoding a…”
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Activation Mechanism of the Streptomyces Tyrosinase Assisted by the Caddie Protein
Published in Biochemistry (Easton) (17-10-2017)“…Tyrosinase (EC 1.14.18.1), which possesses two copper ions at the active center, catalyzes a rate-limiting reaction of melanogenesis, that is, the conversion…”
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Polyphenolic Constituents of Cynomorium songaricum Rupr. and Antibacterial Effect of Polymeric Proanthocyanidin on Methicillin-Resistant Staphylococcus aureus
Published in Journal of agricultural and food chemistry (25-07-2012)“…Oligomeric and polymeric flavan-3-ols were obtained by chromatographic fractionation of extracts from Cynomorium songaricum Rupr. The structure of the…”
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AbeM, an H+-Coupled Acinetobacter baumannii Multidrug Efflux Pump Belonging to the MATE Family of Transporters
Published in Antimicrobial Agents and Chemotherapy (01-10-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Action mechanism of 6, 6′-dihydroxythiobinupharidine from Nuphar japonicum, which showed anti-MRSA and anti-VRE activities
Published in Biochimica et biophysica acta (01-06-2015)“…Multidrug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE), cause serious infections…”
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Functionally cloned pdrM from Streptococcus pneumoniae encodes a Na(+) coupled multidrug efflux pump
Published in PloS one (26-03-2013)“…Multidrug efflux pumps play an important role as a self-defense system in bacteria. Bacterial multidrug efflux pumps are classified into five families based on…”
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Potentiation of Antimicrobial Activity of Aminoglycosides by Carnosol from Salvia officinalis
Published in Biological & Pharmaceutical Bulletin (01-02-2007)“…We found that a crude extract from Salvia officinalis (sage) reduced the minimum inhibitory concentrations (MICs) of aminoglycosides in vancomycin-resistant…”
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