Search Results - "KURIEN, Biji T"

Autoantibodies in Sjögren’s Syndrome by Fayyaz, Anum, MBBS, Kurien, Biji T., PhD, Scofield, Robert Hal, MD

“…We compiled information on antibodies in Sjögren syndrome, focusing more on clinical manifestations associated with anti-Ro/SSA and anti-La/SSB antibodies and…”
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Autoimmunity and oxidatively modified autoantigens by Kurien, Biji T, Scofield, R. Hal

“…Abstract Oxidative damage mediated by reactive oxygen species results in the generation of deleterious by-products. The oxidation process itself and the…”
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The Potential Utility of Salivary and Tear Proteomics to Discriminate Sjögren's Disease from Non-Sjögren's Sicca by George, Christopher T, Kurien, Biji T, Scofield, R Hal

“…Sjögren's Disease (SjD) is an autoimmune disorder associated with decreased saliva and/or tear secretions, resulting in patients reporting dryness in the mouth…”
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Strawberries Improve Pain and Inflammation in Obese Adults with Radiographic Evidence of Knee Osteoarthritis by Schell, Jace, Scofield, R Hal, Barrett, James R, Kurien, Biji T, Betts, Nancy, Lyons, Timothy J, Zhao, Yan Daniel, Basu, Arpita

“…Osteoarthritis (OA), the most common form of arthritis, is a significant public health burden in U.S. adults. Among its many risk factors, obesity is a key…”
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Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21 by Harris, Valerie M, Harley, Isaac T W, Kurien, Biji T, Koelsch, Kristi A, Scofield, Robert Hal

“…and both contain risk alleles for systemic lupus erythematosus (SLE) and Sjögren's syndrome (pSS). The former escapes X inactivation. Our group predicts…”
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Sjögren Syndrome without Focal Lymphocytic Infiltration of the Salivary Glands by Sharma, Rohan, Chaudhari, Kaustubh S, Kurien, Biji T, Grundahl, Kiely, Radfar, Lida, Lewis, David M, Lessard, Christopher J, Li, He, Rasmussen, Astrid, Sivils, Kathy L, Scofield, R Hal

“…Primary Sjögren syndrome (SS) is characterized by a focal lymphocytic infiltrate in exocrine glands. We describe patients who lacked this key feature. We…”
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Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis by Harris, Valerie M, Koelsch, Kristi A, Kurien, Biji T, Harley, Isaac T W, Wren, Jonathan D, Harley, John B, Scofield, R Hal

“…Ninety percent of systemic lupus erythematosus (SLE) patients are women. X chromosome-dosage increases susceptibility to SLE and primary Sjögren's syndrome…”
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Improving the solubility and pharmacological efficacy of curcumin by heat treatment by Kurien, Biji T, Singh, Anil, Matsumoto, Hiroyuki, Scofield, R Hal

“…Lipid peroxidation has been implicated in a variety of diseases. 4-Hydroxy-2-nonenal (HNE), a major oxidation by-product, is cytotoxic, mutagenic, and…”
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A Small Step, a Giant Leap: Somatic Hypermutation of a Single Amino Acid Leads to Anti-La Autoreactivity by Bartsch, Tabea, Arndt, Claudia, Loureiro, Liliana R, Kegler, Alexandra, Puentes-Cala, Edinson, Soto, Javier Andrés, Kurien, Biji T, Feldmann, Anja, Berndt, Nicole, Bachmann, Michael P

“…The anti-La mab 312B, which was established by hybridoma technology from human-La transgenic mice after adoptive transfer of anti-human La T cells,…”
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And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling by Berndt, Nicole, Bippes, Claudia C, Michalk, Irene, Bartsch, Tabea, Arndt, Claudia, Puentes-Cala, Edinson, Soto, Javier Andrés, Loureiro, Liliana R, Kegler, Alexandra, Bachmann, Dominik, Gross, Joanne K, Gross, Tim, Kurien, Biji T, Scofield, R Hal, Farris, A Darise, James, Judith A, Bergmann, Ralf, Schmitz, Marc, Feldmann, Anja, Bachmann, Michael P

“…Decades ago, we and many other groups showed a nucleo-cytoplasmic translocation of La protein in cultured cells. This shuttling of La protein was seen after UV…”
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T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation by Bachmann, Michael P, Bartsch, Tabea, Bippes, Claudia C, Bachmann, Dominik, Puentes-Cala, Edinson, Bachmann, Jennifer, Bartsch, Holger, Arndt, Claudia, Koristka, Stefanie, Loureiro, Liliana R, Kegler, Alexandra, Laube, Markus, Gross, Joanne K, Gross, Tim, Kurien, Biji T, Scofield, R Hal, Farris, A Darise, James, Judith A, Schmitz, Marc, Feldmann, Anja

“…Since the first description of nuclear autoantigens in the late 1960s and early 1970s, researchers, including ourselves, have found it difficult to establish…”
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Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner by Berndt, Nicole, Bippes, Claudia C, Michalk, Irene, Bachmann, Dominik, Bachmann, Jennifer, Puentes-Cala, Edinson, Bartsch, Tabea, Loureiro, Liliana R, Kegler, Alexandra, Bergmann, Ralf, Gross, Joanne K, Gross, Tim, Kurien, Biji T, Scofield, R Hal, Farris, A Darise, James, Judith A, Schmitz, Marc, Fahmy, Karim, Feldmann, Anja, Arndt, Claudia, Bachmann, Michael P

“…According to the literature, the autoantigen La is involved in Cap-independent translation. It was proposed that one prerequisite for this function is the…”
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Other Notable Methods of Membrane Protein Detection: A Brief Review by Kurien, Biji T, Scofield, R Hal

“…Several techniques have been employed to detect proteins on membranes. These include the use of quantum dot luminescent labels, oxyblot immunochemical…”
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Environmentally safe removal/disposal of Coomassie Brilliant Blue from gel destain and used gel stain by Dorri, Yaser, Kurien, Biji T.

“…Gel destaining following Coomassie Brilliant Blue (CBB) staining involves the use of toxic reagents. Here we demonstrate the efficacy of various paper…”
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An overview of Western blotting for determining antibody specificities for immunohistochemistry by Kurien, Biji T, Dorri, Yaser, Dillon, Skyler, Dsouza, Anil, Scofield, R Hal

“…Despite its overall simplicity, protein blotting or Western blotting has been proven to be a powerful procedure for the immunodetection of proteins, especially…”
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47XXY and 47XXX in Scleroderma and Myositis by Scofield, R. Hal, Lewis, Valerie M., Cavitt, Joshua, Kurien, Biji T., Assassi, Shervin, Martin, Javier, Gorlova, Olga, Gregersen, Peter, Lee, Annette, Rider, Lisa G., O'Hanlon, Terrance, Rothwell, Simon, Lilleker, James, Kochi, Yuta, Terao, Chikacshi, Igoe, Ann, Stevens, Wendy, Sahhar, Joanne, Roddy, Janet, Rischmueller, Maureen, Lester, Sue, Proudman, Susanna, Chen, Sixia, Brown, Matthew A., Mayes, Maureen D., Lamb, Janine A., Miller, Frederick W.

“…Objective We undertook this study to examine the X chromosome complement in participants with systemic sclerosis (SSc) as well as idiopathic inflammatory…”
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Affinity purification of autoantibodies from an antigen strip excised from a nitrocellulose protein blot by Kurien, Biji T

“…A method for the affinity purification of autoantibodies from small volumes of human sera using a western blot strip containing a target antigen…”
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Location of immunization and interferon-γ are central to induction of salivary gland dysfunction in Ro60 peptide immunized model of Sjögren's syndrome by Yin, Hongen, Vosters, Jelle L, Roescher, Nienke, D'Souza, Anil, Kurien, Biji T, Tak, Paul P, Chiorini, John A

“…Anti-Ro antibodies can be found in the serum of the majority of patients with Sjögren's syndrome (SS). Immunization with a 60-kDa Ro peptide has been shown to…”
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Degree of modification of Ro60 by the lipid peroxidation by-product 4-hydroxy-2-nonenal may differentially induce Sjögren syndrome or systemic lupus erythematosus in BALB/c mice by Kurien, Biji T., Porter, Andrew, Dorri, Yaser, Iqbal, Saqib, D'Souza, Anil, Singh, Anil, Asfa, Sima, Cartellieri, Marc, Mathias, Kristen, Matsumoto, Hiroyuki, Bachmann, Michael, Hensley, Kenneth, Scofield, R. Hal

“…Our previous work showed that immunization of rabbits with 4-hydroxy-2-nonenal-modified Ro60 (HNE-Ro60) accelerates autoimmunity. We extended this model into…”
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Experimental animal urine collection: a review by Kurien, Biji T, Everds, Nancy E, Scofield, R Hal

“…Animal urine collection is a vital part of veterinary practice for ascertaining animal health and in scientific investigations for assessing the results of…”
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