Search Results - "KURASHIGE, JUNJI"

Controlling Nutritional Status (CONUT) score is a prognostic marker for gastric cancer patients after curative resection by Kuroda, Daisuke, Sawayama, Hiroshi, Kurashige, Junji, Iwatsuki, Masaaki, Eto, Tsugio, Tokunaga, Ryuma, Kitano, Yuki, Yamamura, Kensuke, Ouchi, Mayuko, Nakamura, Kenichi, Baba, Yoshifumi, Sakamoto, Yasuo, Yamashita, Yoichi, Yoshida, Naoya, Chikamoto, Akira, Baba, Hideo

“…Background Controlling Nutritional Status (CONUT), as calculated from serum albumin, total cholesterol concentration, and total lymphocyte count, was…”
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Clinical impact of serum exosomal microRNA‐21 as a clinical biomarker in human esophageal squamous cell carcinoma by Tanaka, Youhei, Kamohara, Hidenobu, Kinoshita, Kouichi, Kurashige, Junji, Ishimoto, Takatsugu, Iwatsuki, Masaaki, Watanabe, Masayuki, Baba, Hideo

“…BACKGROUND: Exosomes are 40‐nm to 100‐nm membrane vesicles that are secreted by various cells, and they play a major role in cell‐cell communication. The…”
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Sarcopenia is a Negative Prognostic Factor After Curative Resection of Colorectal Cancer by Miyamoto, Yuji, Baba, Yoshifumi, Sakamoto, Yasuo, Ohuchi, Mayuko, Tokunaga, Ryuma, Kurashige, Junji, Hiyoshi, Yukiharu, Iwagami, Shiro, Yoshida, Naoya, Yoshida, Megumi, Watanabe, Masayuki, Baba, Hideo

“…Background Skeletal muscle depletion (sarcopenia) is closely associated with limited physical ability and high mortality. This study was performed to evaluate…”
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Sarcopenia is an independent predictor of complications after colorectal cancer surgery by Nakanishi, Ryota, Oki, Eiji, Sasaki, Shun, Hirose, Kosuke, Jogo, Tomoko, Edahiro, Keitaro, Korehisa, Shotaro, Taniguchi, Daisuke, Kudo, Kensuke, Kurashige, Junji, Sugiyama, Masahiko, Nakashima, Yuichiro, Ohgaki, Kippei, Saeki, Hiroshi, Maehara, Yoshihiko

“…Purpose The significance of sarcopenia after colorectal cancer (CRC) resection has only been discussed with relatively small samples or short follow-up…”
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Negative Impact of Skeletal Muscle Loss after Systemic Chemotherapy in Patients with Unresectable Colorectal Cancer by Miyamoto, Yuji, Baba, Yoshifumi, Sakamoto, Yasuo, Ohuchi, Mayuko, Tokunaga, Ryuma, Kurashige, Junji, Hiyoshi, Yukiharu, Iwagami, Shiro, Yoshida, Naoya, Watanabe, Masayuki, Baba, Hideo

“…Skeletal muscle depletion (sarcopenia) is closely associated with limited physical ability and high mortality. This study evaluated the prognostic significance…”
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Preoperative Nutritional Assessment by Controlling Nutritional Status (CONUT) is Useful to estimate Postoperative Morbidity After Esophagectomy for Esophageal Cancer by Yoshida, Naoya, Baba, Yoshifumi, Shigaki, Hironobu, Harada, Kazuto, Iwatsuki, Masaaki, Kurashige, Junji, Sakamoto, Yasuo, Miyamoto, Yuji, Ishimoto, Takatsugu, Kosumi, Keisuke, Tokunaga, Ryuma, Imamura, Yu, Ida, Satoshi, Hiyoshi, Yukiharu, Watanabe, Masayuki, Baba, Hideo

“…Background A nutritional indicator suitable for predicting complications after esophagectomy has not been confirmed. The nutritional screening tool CONUT is a…”
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Prophylactic laparoscopic total gastrectomy for gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): the first report in Asia by Matsumoto, Chihiro, Iwatsuki, Masaaki, Iwagami, Shiro, Morinaga, Takeshi, Yamashita, Kohei, Nakamura, Kenichi, Eto, Kojiro, Kurashige, Junji, Baba, Yoshifumi, Miyamoto, Yuji, Yoshida, Naoya, Komohara, Yoshihiro, Baba, Hideo

“…A 41-year-old woman was admitted to our hospital for epigastralgia. She had been admitted to another hospital for fundic gland polyposis (FGP) without any…”
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CXCL12/CXCR4 activation by cancer‐associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer by Izumi, Daisuke, Ishimoto, Takatsugu, Miyake, Keisuke, Sugihara, Hidetaka, Eto, Kojiro, Sawayama, Hiroshi, Yasuda, Tadahito, Kiyozumi, Yuki, Kaida, Takayoshi, Kurashige, Junji, Imamura, Yu, Hiyoshi, Yukiharu, Iwatsuki, Masaaki, Iwagami, Shiro, Baba, Yoshifumi, Sakamoto, Yasuo, Miyamoto, Yuji, Yoshida, Naoya, Watanabe, Masayuki, Takamori, Hiroshi, Araki, Norie, Tan, Patrick, Baba, Hideo

“…Cancer‐associated fibroblasts (CAFs) are reportedly involved in invasion and metastasis in several types of cancer, including gastric cancer (GC), through the…”
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MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma by Kurashige, Junji, Kamohara, Hidenobu, Watanabe, Masayuki, Hiyoshi, Yukiharu, Iwatsuki, Masaaki, Tanaka, Youhei, Kinoshita, Koichi, Saito, Seiya, Baba, Yoshifumi, Baba, Hideo

“…Background The microRNA-200 (miR-200) family has been reported to induce epithelial differentiation and suppress epithelial–mesenchymal transition (EMT) by…”
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Epigenetic field cancerization in gastrointestinal cancers by Baba, Yoshifumi, Ishimoto, Takatsugu, Kurashige, Junji, Iwatsuki, Masaaki, Sakamoto, Yasuo, Yoshida, Naoya, Watanabe, Masayuki, Baba, Hideo

“…Highlights • Epigenetic alterations, including aberrant DNA methylation, play an important role in human cancer development. • A field for cancerization, or a…”
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Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma by ISHIBASHI, MASAHISA, KOGO, RYUNOSUKE, SHIBATA, KOHEI, SAWADA, GENTA, TAKAHASHI, YUSUKE, KURASHIGE, JUNJI, AKIYOSHI, SAYURI, SASAKI, SHIN, IWAYA, TAKESHI, SUDO, TOMOYA, SUGIMACHI, KEISHI, MIMORI, KOSHI, WAKABAYASHI, GO, MORI, MASAKI

“…The functions of many long non-coding RNAs (ncRNAs) in human cancers have not yet been elucidated. The long ncRNA HOTAIR is expressed from the developmental…”
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Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution by Uchi, Ryutaro, Takahashi, Yusuke, Niida, Atsushi, Shimamura, Teppei, Hirata, Hidenari, Sugimachi, Keishi, Sawada, Genta, Iwaya, Takeshi, Kurashige, Junji, Shinden, Yoshiaki, Iguchi, Tomohiro, Eguchi, Hidetoshi, Chiba, Kenichi, Shiraishi, Yuichi, Nagae, Genta, Yoshida, Kenichi, Nagata, Yasunobu, Haeno, Hiroshi, Yamamoto, Hirofumi, Ishii, Hideshi, Doki, Yuichiro, Iinuma, Hisae, Sasaki, Shin, Nagayama, Satoshi, Yamada, Kazutaka, Yachida, Shinichi, Kato, Mamoru, Shibata, Tatsuhiro, Oki, Eiji, Saeki, Hiroshi, Shirabe, Ken, Oda, Yoshinao, Maehara, Yoshihiko, Komune, Shizuo, Mori, Masaki, Suzuki, Yutaka, Yamamoto, Ken, Aburatani, Hiroyuki, Ogawa, Seishi, Miyano, Satoru, Mimori, Koshi

“…Understanding intratumor heterogeneity is clinically important because it could cause therapeutic failure by fostering evolutionary adaptation. To this end, we…”
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Trastuzumab upregulates programmed death ligand-1 expression through interaction with NK cells in gastric cancer by Yamashita, Kohei, Iwatsuki, Masaaki, Yasuda-Yoshihara, Noriko, Morinaga, Takeshi, Nakao, Yosuke, Harada, Kazuto, Eto, Kojiro, Kurashige, Junji, Hiyoshi, Yukiharu, Ishimoto, Takatsugu, Nagai, Yohei, Iwagami, Shiro, Baba, Yoshifumi, Miyamoto, Yuji, Yoshida, Naoya, Ajani, Jaffer A., Baba, Hideo

“…Background The predictive significance of programmed death ligand 1 (PD-L1) for programmed death 1 (PD-1) inhibitors remains unclear in gastric cancer (GC) due…”
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Current perspectives toward the identification of key players in gastric cancer microRNA dysregulation by Ishimoto, Takatsugu, Baba, Hideo, Izumi, Daisuke, Sugihara, Hidetaka, Kurashige, Junji, Iwatsuki, Masaaki, Tan, Patrick

“…Acquired genetic and epigenetic alterations in normal cells give rise to transformed cells, which lead to tumor development. Elucidation of the precise…”
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Oligometastatic recurrence as a prognostic factor after curative resection of esophageal squamous cell carcinoma by Morinaga, Takeshi, Iwatsuki, Masaaki, Yamashita, Kohei, Harada, Kazuto, Kurashige, Junji, Nagai, Yohei, Iwagami, Shiro, Baba, Yoshihumi, Yoshida, Naoya, Baba, Hideo

“…Purpose In recent years, the concept of oligometastasis, which represents limited metastatic disease, has gained much interest. This study focuses on the…”
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Epigenetic modulation and repression of miR-200b by cancer-associated fibroblasts contribute to cancer invasion and peritoneal dissemination in gastric cancer by Kurashige, Junji, Mima, Kosuke, Sawada, Genta, Takahashi, Yusuke, Eguchi, Hidetoshi, Sugimachi, Keishi, Mori, Masaki, Yanagihara, Kazuyoshi, Yashiro, Masakazu, Hirakawa, Kosei, Baba, Hideo, Mimori, Koshi

“…Cancer-associated fibroblasts (CAFs) have recently been linked to the invasion and metastasis of gastric cancer. In addition, the microRNA (miR)-200 family…”
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PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer by Kiyozumi, Yuki, Iwatsuki, Masaaki, Kurashige, Junji, Ogata, Yoko, Yamashita, Kohei, Koga, Yuki, Toihata, Tasuku, Hiyoshi, Yukiharu, Ishimoto, Takatsugu, Baba, Yoshifumi, Miyamoto, Yuji, Yoshida, Naoya, Yanagihara, Kazuyoshi, Mimori, Koshi, Baba, Hideo

“…Peritoneal dissemination is the most common metastatic pattern in advanced gastric cancer (GC) and has a very poor prognosis. However, its molecular mechanism…”
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The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors by Koga, Yuki, Iwatsuki, Masaaki, Yamashita, Kohei, Kiyozumi, Yuki, Kurashige, Junji, Masuda, Toshiro, Eto, Kojiro, Iwagami, Shiro, Harada, Kazuto, Ishimoto, Takatsugu, Baba, Yoshifumi, Yoshida, Naoya, Miyanari, Nobutomo, Takamori, Hiroshi, Ajani, Jaffer A., Baba, Hideo

“…Background Few reliable prognostic markers have been established despite elucidation of the molecular mechanisms of gastrointestinal stromal tumor (GIST)…”
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Colorectal Cancer Stem Cells Acquire Chemoresistance Through the Upregulation of F‐Box/WD Repeat‐Containing Protein 7 and the Consequent Degradation of c‐Myc by Izumi, Daisuke, Ishimoto, Takatsugu, Miyake, Keisuke, Eto, Tsugio, Arima, Kota, Kiyozumi, Yuki, Uchihara, Tomoyuki, Kurashige, Junji, Iwatsuki, Masaaki, Baba, Yoshifumi, Sakamoto, Yasuo, Miyamoto, Yuji, Yoshida, Naoya, Watanabe, Masayuki, Goel, Ajay, Tan, Patrick, Baba, Hideo

“…The cancer stem cell (CSC) paradigm suggests that tumors are organized hierarchically. Chugai previously established an LGR5+ human colorectal cancer (CRC)…”
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Duration of Smoking Cessation and Postoperative Morbidity After Esophagectomy for Esophageal Cancer: How Long Should Patients Stop Smoking Before Surgery? by Yoshida, Naoya, Baba, Yoshifumi, Hiyoshi, Yukiharu, Shigaki, Hironobu, Kurashige, Junji, Sakamoto, Yasuo, Miyamoto, Yuji, Iwatsuki, Masaaki, Ishimoto, Takatsugu, Kosumi, Keisuke, Sugihara, Hidetaka, Harada, Kazuto, Tokunaga, Ryuma, Izumi, Daisuke, Watanabe, Masayuki, Baba, Hideo

“…Background Smoking is one of the risk factors for postoperative morbidity. There were no studies on the correlation between the duration of smoking cessation…”
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